2V64

Crystallographic structure of the conformational dimer of the Spindle Assembly Checkpoint protein Mad2.

Summary for 2V64

• Entry DOI: 10.2210/pdb2v64/pdb
• Related: 1DUJ 1GO4 1KLQ 1S2H
• Descriptor: MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A, MBP1, ... (4 entities in total)
• Functional Keywords: spindle assembly checkpoint, mad2, nucleus, mitosis, apoptosis, cell cycle, cell division, phosphorylation, conformational dimer
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: Q13257 Q13257
• Total number of polymer chains: 9
• Total formula weight: 149167.73

Authors

Mapelli, M.,Massimiliano, L.,Santaguida, S.,Musacchio, A. (deposition date: 2007-07-13, release date: 2007-11-27, Last modification date: 2023-12-13)

• Primary citation: Mapelli, M.,Massimiliano, L.,Santaguida, S.,Musacchio, A.; The MAD2 Conformational Dimer: Structure and Implications for the Spindle Assembly Checkpoint; Cell(Cambridge,Mass.), 131:730-, 2007; PubMed: 18022367; DOI: 10.1016/J.CELL.2007.08.049

Experimental method

X-RAY DIFFRACTION (2.9 Å)