2V64

Crystallographic structure of the conformational dimer of the Spindle Assembly Checkpoint protein Mad2.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, F (A, C, F)	MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A	polymer	213	24506.9	3	UniProt (Q13257) Pfam (PF02301)	HOMO SAPIENS (HUMAN)	MAD2-LIKE 1, HSMAD2, MAD2
2	B, G, I (B, G, I)	MBP1	polymer	12	1451.6	3		SYNTHETIC CONSTRUCT
3	D, E, H (D, E, H)	MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A	polymer	207	23764.1	3	UniProt (Q13257) Pfam (PF02301)	HOMO SAPIENS (HUMAN)	MAD2-LIKE 1, HSMAD2, MAD2
4	J, K, L (C, F, H)	water	water		18.0	6	Chemie (HOH)

Sequence modifications

A, C, F: -7 - 1 (PDB: 2V64)
A, C, F: 2 - 205 (UniProt: Q13257)
D, E, H: -7 - 1 (PDB: 2V64)
D, E, H: 115 - 117 (PDB: 2V64)
D, E, H: 2 - 108 (UniProt: Q13257)
D, E, H: 118 - 205 (UniProt: Q13257)

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	149167.7
All*	Total formula weight	149167.7

*Water molecules are not included.