PDB: 201 件ウェブページステータス検索Chemie searchBIRD

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7AZB	Structure of DDR2 DS domain in complex with VHH 分子名称: Discoidin domain-containing receptor 2, VHH 著者 Talagas, A, Nawrotek, A, Arrial, A, Vuillard, L.M, Miallau, L. 登録日 2020-11-16 公開日 2020-11-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Structure of DDR2 DS domain in complex with VHH To Be Published
7S0P	Crystal structure of Porcine Factor VIII C2 Domain Bound to Phosphatidylserine 分子名称: Coagulation factor VIII, PHOSPHOSERINE 著者 Peters, S.C, Childers, K.C, Wo, S.W, Brison, C.M, Swanson, C.D, Spiegel, P.C. 登録日 2021-08-30 公開日 2021-10-27 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII. Front Mol Biosci, 9, 2022
3NNG	Crystal structure of the F5/8 type C domain of Q5LFR2_BACFN protein from Bacteroides fragilis. Northeast Structural Genomics Consortium Target BfR258E 分子名称: CALCIUM ION, uncharacterized protein 著者 Vorobiev, S, Su, M, Dimaio, F, Baker, D, Seetharaman, J, Janjua, J, Xiao, R, Ciccosanti, C, Foote, E.L, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2010-06-23 公開日 2010-08-18 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.177 Å) 主引用文献 Crystal structure of the F5/8 type C domain of Q5LFR2_BACFN protein from Bacteroides fragilis. To be Published
5Y4M	Discoidin domain of human CASPR2 分子名称: 1,2-ETHANEDIOL, human CASPR2 Disc domain 著者 Liu, H, Xu, F, Zhang, J, Liang, W. 登録日 2017-08-04 公開日 2018-08-08 最終更新日 2019-02-20 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Structural mapping of hot spots within human CASPR2 discoidin domain for autoantibody recognition. J. Autoimmun., 96, 2019
4XZU	Crystal Structure of the Human Factor VIII C2 Domain in Complex with Murine 3E6 Inhibitory Antibody 分子名称: 3E6 antibody Fab heavy chain, 3E6 antibody Fab light chain, Coagulation factor VIII, ... 著者 Spiegel, P.C, Wuerth, M.E. 登録日 2015-02-05 公開日 2015-12-09 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structure of the Human Factor VIII C2 Domain in Complex with the 3E6 Inhibitory Antibody. Sci Rep, 5, 2015
2LS6	Solution NMR Structure of a Non-canonical galactose-binding CBM32 from Clostridium perfringens 分子名称: Hyaluronoglucosaminidase 著者 Grondin, J.M, Chitayat, S, Ficko-Blean, E, Boraston, A.B, Smith, S.P. 登録日 2012-04-20 公開日 2013-05-01 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 An unusual mode of galactose recognition by a family 32 carbohydrate-binding module. J.Mol.Biol., 426, 2014
6OE2	X-Ray Structure of the C-terminal domain (277-440) of Putative chitobiase from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium Target BtR324A. Re-refinement of 3GGL with correct metal Mn replacing Zn. New metal confirmed with PIXE analysis of original sample. 分子名称: Chitobiase, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION 著者 Snell, E.H, Garman, E.F, Lowe, E.D. 登録日 2019-03-27 公開日 2019-12-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 High-Throughput PIXE as an Essential Quantitative Assay for Accurate Metalloprotein Structural Analysis: Development and Application. J.Am.Chem.Soc., 142, 2020
8PFE	Crystal Structure of an Hexavariant of the b1 Domain of Human Neuropilin-1 in Complex with the KDKPPR Peptide 分子名称: ACETATE ION, LYS-ASP-LYS-PRO-PRO-ARG, Neuropilin-1 著者 Jelsch, C, Favier, F, Didierjean, C. 登録日 2023-06-15 公開日 2023-08-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 New Crystal Form of Human Neuropilin-1 b1 Fragment with Six Electrostatic Mutations Complexed with KDKPPR Peptide Ligand. Molecules, 28, 2023
7RGA	Crystal structure of nanoCLAMP3:VHH in complex with MTX 分子名称: METHOTREXATE, SODIUM ION, nano CLostridial Antibody Mimetic Protein 3 VHH 著者 Guo, Z, Alexandrov, K. 登録日 2021-07-14 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Design of a methotrexate-controlled chemical dimerization system and its use in bio-electronic devices. Nat Commun, 12, 2021
9EOU	Crystal Structure of the b1b2 domains from Human Neuropilin-1 in complex with a peptide. 分子名称: Neuropilin-1, Osteopontin 著者 Caing-Carlsson, R, Duelli, A, Walse, B. 登録日 2024-03-15 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis. Pharmacol Res, 205, 2024
9D5D	Crystal Structure of Blood Coagulation Factor VIII C2 Domain Mutant L2251A/L2252A 分子名称: Factor VIIIa light chain 著者 Avery, N.G, Childers, K.C, Spiegel, P.C. 登録日 2024-08-13 公開日 2024-09-04 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Biophysical characterization of blood coagulation factor VIII binding to lipid nanodiscs that mimic activated platelet surfaces To Be Published
4LKS	Structure of CBM32-3 from a family 31 glycoside hydrolase from Clostridium perfringens in complex with galactose 分子名称: CALCIUM ION, Glycosyl hydrolase, family 31/fibronectin type III domain protein, ... 著者 Grondin, J.M, Duan, D, Kirlin, A.C, Furness, H.S, Allingham, J.S, Smith, S.P. 登録日 2013-07-08 公開日 2014-12-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Diverse modes of galacto-specific carbohydrate recognition by a family 31 glycoside hydrolase from Clostridium perfringens. Plos One, 12, 2017
4LPL	Structure of CBM32-1 from a family 31 glycoside hydrolase from Clostridium perfringens 分子名称: CALCIUM ION, Glycosyl hydrolase, family 31/fibronectin type III domain protein, ... 著者 Grondin, J.M, Duan, D, Heather, F.S, Spencer, C.A, Allingham, J.S, Smith, S.P. 登録日 2013-07-16 公開日 2014-07-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Diverse modes of galacto-specific carbohydrate recognition by a family 31 glycoside hydrolase from Clostridium perfringens. Plos One, 12, 2017
2Z4F	Solution structure of the Discoidin Domain of DDR2 分子名称: Discoidin domain-containing receptor 2 著者 Ichikawa, O, Osawa, M, Nishida, N, Goshima, N, Nomura, N, Shimada, I. 登録日 2007-06-16 公開日 2007-09-04 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Structural basis of the collagen-binding mode of discoidin domain receptor 2 Embo J., 26, 2007
6FMC	Neuropilin1-b1 domain in complex with EG01377, 0.9 Angstrom structure 分子名称: (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1 著者 Yelland, T, Djordjevic, S, Fotinou, K, Selwood, D, Zachary, I, Frankel, P. 登録日 2018-01-30 公開日 2018-10-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (0.9 Å) 主引用文献 Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells. J. Med. Chem., 61, 2018
5N6W	Retinoschisin R141H Mutant 分子名称: Retinoschisin 著者 Ramsay, E.P, Collins, R.F, Owens, T.W, Siebert, C.A, Jones, R.P.O, Roseman, A, Wang, T, Baldock, C. 登録日 2017-02-16 公開日 2017-04-12 最終更新日 2017-08-30 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural analysis of X-linked retinoschisis mutations reveals distinct classes which differentially effect retinoschisin function Human Molecular Genetics, 25, 2016
5IJR	X-ray structure of neuropilin-1 b1 domain complexed with Arg-1 ligand. 分子名称: DIMETHYL SULFOXIDE, L-HOMOARGININE, Neuropilin-1 著者 Fotinou, C, Rana, R, Djordjevic, S, Yelland, T. 登録日 2016-03-02 公開日 2017-03-29 最終更新日 2018-07-11 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Architecture and hydration of the arginine-binding site of neuropilin-1. FEBS J., 285, 2018
6FMF	Neuropilin-1 b1 domain in complex with EG01377; 2.8 Angstrom structure 分子名称: (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1, trifluoroacetic acid 著者 Yelland, T, Djordjevic, S, Selwood, D, Zachary, I, Frankel, P. 登録日 2018-01-31 公開日 2018-10-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.811 Å) 主引用文献 Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells. J. Med. Chem., 61, 2018
5IYY	X-ray structure of neuropilin-1 b1 domain complexed with Arg-4 ligand. 分子名称: Neuropilin-1, N~2~-[(benzyloxy)carbonyl]-L-arginine 著者 Fotinou, C, Rana, R, Djordjevic, S, Yelland, T. 登録日 2016-03-24 公開日 2017-04-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Architecture and hydration of the arginine-binding site of neuropilin-1. FEBS J., 285, 2018
4KI5	Cystal structure of human factor VIII C2 domain in a ternary complex with murine inhbitory antibodies 3E6 and G99 分子名称: Coagulation factor VIII, MURINE MONOCLONAL 3E6 FAB HEAVY CHAIN, MURINE MONOCLONAL 3E6 FAB LIGHT CHAIN, ... 著者 Walter, J.D, Meeks, S.L, Healey, J.F, Lollar, P, Spiegel, P.C. 登録日 2013-05-01 公開日 2014-01-15 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Structure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopes. Blood, 122, 2013
5C7G	Crystal Structure of the b1 Domain of Human Neuropilin-1 in complex with a bicine molecule 分子名称: BICINE, Neuropilin-1, SODIUM ION 著者 Didierjean, C, Jelsch, C. 登録日 2015-06-24 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Design, synthesis and biological evaluation of new peptidomimetic compounds targeting NRP-1 receptor TO BE PUBLISHED To Be Published
7O1N	Crystal Structure of Human Neuropilin-1 b1 Domain mutant - Y297A 分子名称: Neuropilin-1 著者 Djordjevic, S, Chandanani, J, Faleeva, M, Pinotsis, N. 登録日 2021-03-29 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Crystal Structure of Human Neuropilin-1 b1 Domain mutant - Y297A To Be Published
1IQD	Human Factor VIII C2 Domain complexed to human monoclonal BO2C11 Fab. 分子名称: HUMAN FACTOR VIII, HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN, HUMAN MONOCLONAL BO2C11 FAB LIGHT CHAIN 著者 Spiegel Jr, P.C, Jacquemin, M, Saint-Remy, J.M, Stoddard, B.L, Pratt, K.P. 登録日 2001-07-21 公開日 2001-08-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of a factor VIII C2 domain-immunoglobulin G4kappa Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII. Blood, 98, 2001
1TVG	X-ray structure of human PP25 gene product, HSPC034. Northeast Structural Genomics Target HR1958. 分子名称: CALCIUM ION, LOC51668 protein, SAMARIUM (III) ION 著者 Kuzin, A.P, Vorobiev, S.M, Lee, I, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2004-06-29 公開日 2004-11-09 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study. Proteins, 75, 2009
7P5U	Neuropilin-b1 in a complex with a VEGFB-derived peptide 分子名称: MGC0122, Neuropilin-1 著者 Fotinou, C, Rhana, R, Yelland, T. 登録日 2021-07-14 公開日 2022-07-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Neuropilin-b1 in a complex with a VEGFB-derived peptide To Be Published

 

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