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1IRS
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BU of 1irs by Molmil
IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: IL-4 RECEPTOR PHOSPHOPEPTIDE, IRS-1
Authors:Zhou, M.-M, Huang, B, Olejniczak, E.T, Meadows, R.P, Shuker, S.B, Miyazaki, M, Trub, T, Shoelson, S.E, Feisk, S.W.
Deposit date:1996-03-22
Release date:1997-05-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.
Nat.Struct.Biol., 3, 1996
1QQG
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BU of 1qqg by Molmil
CRYSTAL STRUCTURE OF THE PH-PTB TARGETING REGION OF IRS-1
Descriptor: INSULIN RECEPTOR SUBSTRATE 1
Authors:Dhe-Paganon, S, Shoelson, S.E.
Deposit date:1999-06-04
Release date:1999-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1.
Proc.Natl.Acad.Sci.USA, 96, 1999
1MIX
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BU of 1mix by Molmil
Crystal structure of a FERM domain of Talin
Descriptor: Talin
Authors:Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MIZ
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Crystal structure of an integrin beta3-talin chimera
Descriptor: TALIN, integrin beta3
Authors:Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MK7
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CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor: Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1MK9
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CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor: Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1J0W
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BU of 1j0w by Molmil
Crystal Structure Analysis of the Dok-5 PTB Domain
Descriptor: downstream of tyrosine kinase 5
Authors:Shi, N, Ding, Y, Qiang, B.Q, Yuan, J.G, Rao, Z.H.
Deposit date:2002-11-25
Release date:2003-12-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure Analysis of the Dok-5 PTB Domain
To be Published
1P5T
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BU of 1p5t by Molmil
Crystal Structure of Dok1 PTB Domain
Descriptor: Docking protein 1
Authors:Shi, N, Ye, S, Liu, Y, Zhou, W, Ding, Y, Lou, Z, Qiang, B, Yuan, J, Rao, Z.
Deposit date:2003-04-28
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
J.BIOL.CHEM., 279, 2004
1UEF
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BU of 1uef by Molmil
Crystal Structure of Dok1 PTB Domain Complex
Descriptor: 13-mer peptide from Proto-oncogene tyrosine-protein kinase receptor ret, Docking protein 1
Authors:Shi, N, Ye, S, Liu, Y, Zhou, W, Ding, Y, Lou, Z, Qiang, B, Yan, J, Rao, Z.
Deposit date:2003-05-14
Release date:2004-05-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
J.Biol.Chem., 279, 2004
1XR0
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BU of 1xr0 by Molmil
Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
Descriptor: Basic fibroblast growth factor receptor 1, FGFR signalling adaptor SNT-1
Authors:Dhalluin, C, Yan, K.S, Plotnikova, O, Lee, K.W, Zeng, L, Kuti, M, Mujtaba, S, Goldfarb, M.P, Zhou, M.-M.
Deposit date:2004-10-13
Release date:2004-11-02
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
Mol.Cell, 6, 2000
1Y19
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BU of 1y19 by Molmil
Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
Descriptor: Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1
Authors:de Pereda, J.M, Wegener, K, Santelli, E, Bate, N, Ginsberg, M.H, Critchley, D.R, Campbell, I.D, Liddington, R.C.
Deposit date:2004-11-17
Release date:2005-01-04
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
J.Biol.Chem., 280, 2005
2G35
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BU of 2g35 by Molmil
NMR structure of talin-PTB in complex with PIPKI
Descriptor: Talin-1, peptide
Authors:Kong, X, Wang, X, Misra, S, Qin, J.
Deposit date:2006-02-17
Release date:2006-05-02
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structural Basis for the Phosphorylation-regulated Focal Adhesion Targeting of Type Igamma Phosphatidylinositol Phosphate Kinase (PIPKIgamma) by Talin.
J.Mol.Biol., 359, 2006
2DLW
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BU of 2dlw by Molmil
Solution structure of the IRS domain of human docking protein 2, isoform a
Descriptor: Docking protein 2, isoform a
Authors:Zhang, H.P, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-20
Release date:2006-10-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the IRS domain of human docking protein 2, isoform a
to be published
2H7E
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BU of 2h7e by Molmil
Solution structure of the talin F3 domain in complex with a chimeric beta3 integrin-PIP kinase peptide- minimized average structure
Descriptor: Chimera of 24-mer peptide from Integrin beta-3 and 10-mer peptide from Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma, Talin-1
Authors:Wegener, K.L.
Deposit date:2006-06-02
Release date:2007-01-30
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Structural basis of integrin activation by talin
CELL(CAMBRIDGE,MASS.), 128, 2007
2H7D
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BU of 2h7d by Molmil
Solution structure of the talin F3 domain in complex with a chimeric beta3 integrin-PIP kinase peptide
Descriptor: Chimera of 24-mer peptide from Integrin beta-3 and 10-mer peptide from Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma, Talin-1
Authors:Wegener, K.L.
Deposit date:2006-06-02
Release date:2007-01-30
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Structural basis of integrin activation by talin
CELL(CAMBRIDGE,MASS.), 128, 2007
2YS5
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BU of 2ys5 by Molmil
Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK
Descriptor: ALK tyrosine kinase receptor, Fibroblast growth factor receptor substrate 3
Authors:Li, H, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-03
Release date:2008-04-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
2YT2
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BU of 2yt2 by Molmil
Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK
Descriptor: Fibroblast growth factor receptor substrate 3 and ALK tyrosine kinase receptor
Authors:Li, H, Koshiba, S, Tomizawa, T, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2008-04-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
2V76
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BU of 2v76 by Molmil
Crystal structure of the human dok1 PTB domain
Descriptor: 1,2-ETHANEDIOL, DOCKING PROTEIN 1, GLYCEROL, ...
Authors:Oxley, C.L, Anthis, N.J, Lowe, E.D, Campbell, I.D, Wegener, K.L.
Deposit date:2007-07-26
Release date:2008-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:An Integrin Phosphorylation Switch: The Effect of {Beta}3 Integrin Tail Phosphorylation on Dok1 and Talin Binding.
J.Biol.Chem., 283, 2008
2K00
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BU of 2k00 by Molmil
Solution structure of the talin F3 in complex with layilin cytodomain
Descriptor: Layilin, Talin-1
Authors:Wegener, K.L, Barsukov, I.L.
Deposit date:2008-01-23
Release date:2008-09-09
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural basis for the interaction between the cytoplasmic domain of the hyaluronate receptor layilin and the talin F3 subdomain
J.Mol.Biol., 382, 2008
3G9W
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BU of 3g9w by Molmil
Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ...
Authors:Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D.
Deposit date:2009-02-15
Release date:2009-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.165 Å)
Cite:The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
Embo J., 28, 2009
2KGX
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BU of 2kgx by Molmil
HADDOCK structure of the talin F3 domain in complex with talin 1655-1822
Descriptor: MKIAA1027 protein, Talin-1
Authors:Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R, Barsukov, I.L.
Deposit date:2009-03-23
Release date:2009-03-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structure of an interdomain complex that regulates talin activity.
J.Biol.Chem., 284, 2009
3IVF
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BU of 3ivf by Molmil
Crystal structure of the talin head FERM domain
Descriptor: Talin-1
Authors:Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
Deposit date:2009-09-01
Release date:2010-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The Structure of the talin head reveals a novel extended conformation of the FERM domain
Structure, 18, 2010
2KUP
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BU of 2kup by Molmil
Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK
Descriptor: 19-residue peptide from ALK tyrosine kinase receptor, Fibroblast growth factor receptor substrate 3
Authors:Li, H, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2010-02-24
Release date:2010-05-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
2KUQ
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BU of 2kuq by Molmil
Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK
Descriptor: Fibroblast growth factor receptor substrate 3,LINKER,ALK tyrosine kinase receptor
Authors:Li, H, Koshiba, S, Tomizawa, T, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2010-02-24
Release date:2010-05-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
3ML4
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BU of 3ml4 by Molmil
Crystal structure of a complex between Dok7 PH-PTB and the MuSK juxtamembrane region
Descriptor: Muscle, skeletal receptor tyrosine-protein kinase, Protein Dok-7
Authors:Bergamin, E, Hubbard, S.R.
Deposit date:2010-04-16
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization.
Mol.Cell, 39, 2010

 

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