2KUP

Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK

Summary for 2KUP

Related2YS5
DescriptorFibroblast growth factor receptor substrate 3, 19-residue peptide from ALK tyrosine kinase receptor (2 entities in total)
Functional Keywordscomplex, snt-2, ptb domain, halk, structural genomics, signaling protein, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, signaling protein-oncoprotein complex, signaling protein/oncoprotein
Biological sourceHomo sapiens (human)
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Cellular locationMembrane; Lipid-anchor O43559
Cell membrane; Single-pass type I membrane protein Q9UM73
Total number of polymer chains2
Total molecular weight18675.92
Authors
Li, H.,Koshiba, S.,Inoue, M.,Kigawa, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2010-02-24, release date: 2010-05-26, Last modification date: 2014-02-12)
Primary citation
Koshiba, S.,Li, H.,Motoda, Y.,Tomizawa, T.,Kasai, T.,Tochio, N.,Yabuki, T.,Harada, T.,Watanabe, S.,Tanaka, A.,Shirouzu, M.,Kigawa, T.,Yamamoto, T.,Yokoyama, S.
Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11:125-141, 2010
PubMed: 20454865 (PDB entries with the same primary citation)
DOI: 10.1007/s10969-010-9091-x
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers006.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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