1XR0

Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors

Summary for 1XR0

• Entry DOI: 10.2210/pdb1xr0/pdb
• Descriptor: Basic fibroblast growth factor receptor 1, FGFR signalling adaptor SNT-1 (2 entities in total)
• Functional Keywords: fgfr, snt, phosphotyrosine binding domain, ptb, trk, npxpy motif, signaling protein-growth factor receptor complex, signaling protein/growth factor receptor
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P11362; Endomembrane system: Q8WU20
• Total number of polymer chains: 2
• Total formula weight: 17498.77

Authors

Dhalluin, C.,Yan, K.S.,Plotnikova, O.,Lee, K.W.,Zeng, L.,Kuti, M.,Mujtaba, S.,Goldfarb, M.P.,Zhou, M.-M. (deposition date: 2004-10-13, release date: 2004-11-02, Last modification date: 2022-03-02)

• Primary citation: Dhalluin, C.,Yan, K.S.,Plotnikova, O.,Lee, K.W.,Zeng, L.,Kuti, M.,Mujtaba, S.,Goldfarb, M.P.,Zhou, M.-M.; Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors; Mol.Cell, 6:921-929, 2000; PubMed: 11090629; DOI: 10.1016/S1097-2765(05)00087-0

Experimental method

SOLUTION NMR