1MIZ

Crystal structure of an integrin beta3-talin chimera

Summary for 1MIZ

Entry DOI	10.2210/pdb1miz/pdb
Related	1MIX 1MK7 1MK9
Descriptor	integrin beta3, TALIN (3 entities in total)
Functional Keywords	focal adhesion, integrin binding, cytoskeleton, npxy motif, ptb domain, structural protein
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P05106 Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side: P54939
Total number of polymer chains	2
Total formula weight	24127.59
Authors	Garcia-Alvarez, B.,de Pereda, J.M.,Calderwood, D.A.,Ulmer, T.S.,Critchley, D.,Campbell, I.D.,Ginsberg, M.H.,Liddington, R.C. (deposition date: 2002-08-23, release date: 2003-01-28, Last modification date: 2011-07-13)
Primary citation	Garcia-Alvarez, B.,de Pereda, J.M.,Calderwood, D.A.,Ulmer, T.S.,Critchley, D.,Campbell, I.D.,Ginsberg, M.H.,Liddington, R.C. Structural determinants of integrin recognition by talin Mol.Cell, 11:49-58, 2003 Cited by PubMed: 12535520 DOI: 10.1016/S1097-2765(02)00823-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation