6XLU | | STRUCTURE OF SARS-COV-2 SPIKE AT PH 4.0 | | Descriptor: | Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Zhou, T., Tsybovsky, Y., Olia, A., Kwong, P.D. | | Deposit date: | 2020-06-29 | | Release date: | 2020-08-12 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains
Biorxiv, 2020
|
|
7CAH | | THE INTERFACE OF H014 FAB BINDS TO SARS-COV-2 S | | Descriptor: | Light chain of H014 Fab, Heavy chain of H014 Fab, Spike glycoprotein | | Authors: | Zhe, L., Cao, L., Deng, Y., Sun, Y., Wang, N., Xie, L., Rao, Z., wang, Y., Qin, C., Wang, X. | | Deposit date: | 2020-06-08 | | Release date: | 2020-08-12 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody.
Science, 2020
|
|
6XM3 | | STRUCTURE OF SARS-COV-2 SPIKE AT PH 5.5, SINGLE RBD UP, CONFORMATION 1 | | Descriptor: | Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Zhou, T., Tsybovsky, Y., Olia, A., Kwong, P.D. | | Deposit date: | 2020-06-29 | | Release date: | 2020-08-12 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains
Biorxiv, 2020
|
|
6XM0 | | CONSENSUS STRUCTURE OF SARS-COV-2 SPIKE AT PH 5.5 | | Descriptor: | Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Zhou, T., Tsybovsky, Y., Olia, A., Kwong, P.D. | | Deposit date: | 2020-06-29 | | Release date: | 2020-08-12 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains
Biorxiv, 2020
|
|
6ZRU | | CRYSTAL STRUCTURE OF SARS COV2 MAIN PROTEASE IN COMPLEX WITH INHIBITOR BOCEPREVIR | | Descriptor: | Main Protease, DIMETHYL SULFOXIDE, boceprevir (bound form) | | Authors: | Oerlemans, R., Wang, W., Lunev, S., Domling, A., Groves, M.R. | | Deposit date: | 2020-07-14 | | Release date: | 2020-08-12 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of SARS CoV2 main protease in complex with inhibitor Boceprevir
To Be Published
|
|
7JN2 | | THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2 IN COMPLEX WITH PLP_SNYDER441 | | Descriptor: | Papain-Like Protease, 3-amino-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide, ZINC ION, ... | | Authors: | Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2020-08-03 | | Release date: | 2020-08-12 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | The crystal structure of Papain-Like Protease of SARS CoV-2 in complex with PLP_Snyder441
to be published
|
|
6XM4 | | STRUCTURE OF SARS-COV-2 SPIKE AT PH 5.5, SINGLE RBD UP, CONFORMATION 2 | | Descriptor: | Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Zhou, T., Tsybovsky, Y., Olia, A., Kwong, P.D. | | Deposit date: | 2020-06-29 | | Release date: | 2020-08-12 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains
Biorxiv, 2020
|
|
6ZRT | | CRYSTAL STRUCTURE OF SARS COV2 MAIN PROTEASE IN COMPLEX WITH INHIBITOR TELAPREVIR | | Descriptor: | Main Protease, DIMETHYL SULFOXIDE, (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide | | Authors: | Oerlemans, R., Wang, W., Lunev, S., Domling, A., Groves, M.R. | | Deposit date: | 2020-07-14 | | Release date: | 2020-08-12 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of SARS CoV2 main protease in complex with inhibitor Telaprevir
To Be Published
|
|
7JIT | | THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2 , C111S MUTANT, IN COMPLEX WITH PLP_SNYDER495 | | Descriptor: | Papain-like protease, 5-[(carbamoylcarbamoyl)amino]-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide, ZINC ION, ... | | Authors: | Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2020-07-23 | | Release date: | 2020-08-05 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant, in complex with PLP_Snyder495
to be published
|
|
7JIW | | THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2 IN COMPLEX WITH PLP_SNYDER530 | | Descriptor: | Papain-Like Protease, 5-(acryloylamino)-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide, ZINC ION, ... | | Authors: | Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2020-07-23 | | Release date: | 2020-08-05 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The crystal structure of Papain-Like Protease of SARS CoV-2 in complex with PLP_Snyder530
to be published
|
|
7JIV | | THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2 , C111S MUTANT, IN COMPLEX WITH PLP_SNYDER530 | | Descriptor: | Papain-like protease, 5-(acryloylamino)-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide, ZINC ION, ... | | Authors: | Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2020-07-23 | | Release date: | 2020-08-05 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant, in complex with PLP_Snyder530
to be published
|
|
7JIR | | THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2 , C111S MUTANT, IN COMPLEX WITH PLP_SNYDER457 | | Descriptor: | Papain-like protease, 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, ZINC ION, ... | | Authors: | Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2020-07-23 | | Release date: | 2020-08-05 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant, in complex with PLP_Snyder457
to be published
|
|
6WC1 | |
6ZLW | | SARS-COV-2 NSP1 BOUND TO THE HUMAN 40S RIBOSOMAL SUBUNIT | | Descriptor: | 40S ribosomal protein SA, 40S ribosomal protein S3a, 40S ribosomal protein S2, ... | | Authors: | Thoms, M., Buschauer, R., Ameismeier, M., Denk, T., Kratzat, H., Mackens-Kiani, T., Cheng, J., Berninghausen, O., Becker, T., Beckmann, R. | | Deposit date: | 2020-07-01 | | Release date: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 2020
|
|
6ZP7 | | SARS-COV-2 SPIKE IN PREFUSION STATE (FLEXIBILITY ANALYSIS, 1-UP OPEN CONFORMATION) | | Descriptor: | Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Martinez, M., Marabini, R., Carazo, J.M. | | Deposit date: | 2020-07-08 | | Release date: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures.
Biorxiv, 2020
|
|
6ZON | | SARS-COV-2 NSP1 BOUND TO A HUMAN 43S PREINITIATION RIBOSOME COMPLEX - STATE 1 | | Descriptor: | 40S ribosomal protein SA, 40S ribosomal protein S3a, 40S ribosomal protein S2, ... | | Authors: | Thoms, M., Buschauer, R., Ameismeier, M., Denk, T., Kratzat, H., Mackens-Kiani, T., Cheng, J., Berninghausen, O., Becker, T., Beckmann, R. | | Deposit date: | 2020-07-07 | | Release date: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 2020
|
|
6ZSL | | CRYSTAL STRUCTURE OF THE SARS-COV-2 HELICASE AT 1.94 ANGSTROM RESOLUTION | | Descriptor: | SARS-CoV-2 helicase NSP13, ZINC ION, PHOSPHATE ION | | Authors: | Newman, J.A., Yosaatmadja, Y., Douangamath, A., Arrowsmith, C.H., von Delft, F., Edwards, A., Bountra, C., Gileadi, O. | | Deposit date: | 2020-07-15 | | Release date: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Crystal structure of the SARS-CoV-2 helicase at 1.94 Angstrom resolution
To Be Published
|
|
6ZOW | | SARS-COV-2 SPIKE IN PREFUSION STATE | | Descriptor: | Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Martinez, M., Marabini, R., Carazo, J.M. | | Deposit date: | 2020-07-07 | | Release date: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures.
Biorxiv, 2020
|
|
7C7P | | CRYSTAL STRUCTURE OF THE SARS-COV-2 MAIN PROTEASE IN COMPLEX WITH TELAPREVIR | | Descriptor: | main protease, (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide, CHLORIDE ION, ... | | Authors: | Zeng, R., Qiao, J.X., Wang, Y.F., Li, Y.S., Yao, R., Yang, S.Y., Lei, J. | | Deposit date: | 2020-05-26 | | Release date: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Crystal structure of the SARS-CoV-2 main protease in complex with Telaprevir
To Be Published
|
|
7JFQ | | THE CRYSTAL STRUCTURE OF 3CL MAINPRO OF SARS-COV-2 WITH DE-OXIDIZED C145 | | Descriptor: | 3C-like proteinase, 1,2-ETHANEDIOL, FORMIC ACID | | Authors: | Tan, K., Maltseva, N.I., Welk, L.F., Jedrzejczak, R.P., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2020-07-17 | | Release date: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | The crystal structure of 3CL MainPro of SARS-CoV-2 with de-oxidized C145
To Be Published
|
|
6XM5 | | STRUCTURE OF SARS-COV-2 SPIKE AT PH 5.5, ALL RBDS DOWN | | Descriptor: | Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Zhou, T., Tsybovsky, Y., Olia, A., Kwong, P.D. | | Deposit date: | 2020-06-29 | | Release date: | 2020-07-29 | | Last modified: | 2020-08-12 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains
Biorxiv, 2020
|
|
6XQB | | SARS-COV-2 RDRP/RNA COMPLEX | | Descriptor: | RNA-directed RNA polymerase, Non-structural protein 8, Non-structural protein 7, ... | | Authors: | Liu, B., Shi, W., Yang, Y. | | Deposit date: | 2020-07-09 | | Release date: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of SARS-CoV-2 RdRp/RNA complex at 3.4 Angstroms resolution
To Be Published
|
|
6ZDG | | ASSOCIATION OF THREE COMPLEXES OF LARGELY STRUCTURALLY DISORDERED SPIKE ECTODOMAIN WITH BOUND EY6A FAB | | Descriptor: | Spike glycoprotein, EY6A heavy chain, EY6A light chain, ... | | Authors: | Duyvesteyn, H.M.E., Zhou, D., Zhao, Y., Fry, E.E., Ren, J., Stuart, D.I. | | Deposit date: | 2020-06-14 | | Release date: | 2020-07-29 | | Last modified: | 2020-08-12 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Nat.Struct.Mol.Biol., 2020
|
|
6XEZ | | STRUCTURE OF SARS-COV-2 REPLICATION-TRANSCRIPTION COMPLEX BOUND TO NSP13 HELICASE - NSP13(2)-RTC | | Descriptor: | nsp12, nsp8, nsp7, ... | | Authors: | Chen, J., Malone, B., Llewellyn, E.C., Campbell, E.A., Darst, S.A. | | Deposit date: | 2020-06-14 | | Release date: | 2020-07-29 | | Last modified: | 2020-08-05 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex.
Biorxiv, 2020
|
|
6ZBP | | H11-H4 COMPLEX WITH SARS-COV-2 | | Descriptor: | Spike glycoprotein, H11-H4, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Naismith, J.H., Huo, J., Mikolajek, H., Ward, P., Dumoux, M., Owens, R.J., LeBas, A. | | Deposit date: | 2020-06-08 | | Release date: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | H11-D4 complex with SARS-CoV-2 RBD
To Be Published
|
|
