6W61

Crystal Structure of the methyltransferase-stimulatory factor complex of NSP16 and NSP10 from SARS CoV-2.

Summary for 6W61

• Entry DOI: 10.2210/pdb6w61/pdb
• Related: 6W4H
• Descriptor: 2'-O-methyltransferase, Non-structural protein 10, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: sars corona virus, sam-dependent methyltransferase, structural genomics, center for structural genomics of infectious diseases, csgid, nsp16, nsp10, complex, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 2
• Total formula weight: 49214.48

Authors

Kim, Y.,Jedrzejczak, R.,Maltseva, N.,Endres, M.,Godzik, A.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-03-15, release date: 2020-03-25, Last modification date: 2023-11-15)

• Primary citation: Rosas-Lemus, M.,Minasov, G.,Shuvalova, L.,Inniss, N.L.,Kiryukhina, O.,Wiersum, G.,Kim, Y.,Jedrzejczak, R.,Maltseva, N.I.,Endres, M.,Jaroszewski, L.,Godzik, A.,Joachimiak, A.,Satchell, K.J.F.; The crystal structure of nsp10-nsp16 heterodimer from SARS-CoV-2 in complex with S-adenosylmethionine; Biorxiv, 2020; DOI: 10.1101/2020.04.17.047498

Experimental method

X-RAY DIFFRACTION (2 Å)