6W4H

1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex from SARS-CoV-2

Summary for 6W4H

• Entry DOI: 10.2210/pdb6w4h/pdb
• Descriptor: 2'-O-methyltransferase, Non-structural protein 10, SULFITE ION, ... (8 entities in total)
• Functional Keywords: structural genomics, center for structural genomics of infectious diseases, csgid, nsp16, nsp10, complex, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 2
• Total formula weight: 49790.41

Authors

Minasov, G.,Shuvalova, L.,Rosas-Lemus, M.,Kiryukhina, O.,Wiersum, G.,Godzik, A.,Jaroszewski, L.,Stogios, P.J.,Skarina, T.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-03-10, release date: 2020-03-18, Last modification date: 2023-10-18)

• Primary citation: Rosas-Lemus, M.,Minasov, G.,Shuvalova, L.,Inniss, N.L.,Kiryukhina, O.,Brunzelle, J.,Satchell, K.J.F.; High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.; Sci.Signal., 13:-, 2020; PubMed: 32994211; DOI: 10.1126/scisignal.abe1202

Experimental method

X-RAY DIFFRACTION (1.8 Å)