7NLL
 
 | |
7NS6
 
 | SARS-CoV-2 Spike (dimers) in complex with six Fu2 nanobodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fu2 nanobody, Spike glycoprotein,Fibritin, ... | Authors: | Das, H, Hallberg, B.M. | Deposit date: | 2021-03-05 | Release date: | 2022-02-02 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo. Nat Commun, 13, 2022
|
|
7NT4
 
 | X-ray structure of SCoV2-PLpro in complex with small molecule inhibitor | Descriptor: | 1,2-ETHANEDIOL, Non-structural protein 3, PROFLAVIN, ... | Authors: | Napolitano, V, Mourao, A, Bostock, M, Matsuda, A, Czarna, A, Popowicz, G.M. | Deposit date: | 2021-03-09 | Release date: | 2022-02-02 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses. Cell Chem Biol, 29, 2022
|
|
7PQY
 
 | Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FI-3A Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, FI-3A Fab heavy chain, FI-3A Fab light chain, ... | Authors: | Zhou, D, Ren, J, Stuart, D. | Deposit date: | 2021-09-20 | Release date: | 2022-02-02 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2. Theranostics, 12, 2022
|
|
7PQZ
 
 | Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FI-3A and FD-11A Fabs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FD-11A Fab heavy chain, FD-11A Fab light chain, ... | Authors: | Zhou, D, Ren, J, Stuart, D.I. | Deposit date: | 2021-09-20 | Release date: | 2022-02-02 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2. Theranostics, 12, 2022
|
|
7PR0
 
 | Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FD-5D Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, FD-5D Fab heavy chain, ... | Authors: | Zhou, D, Ren, J, Stuart, D.I. | Deposit date: | 2021-09-20 | Release date: | 2022-02-02 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2. Theranostics, 12, 2022
|
|
7QIF
 
 | Crystal structure of SARS-CoV-2 NSP14 in complex with 7MeGpppG. | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, PHOSPHATE ION, Proofreading exoribonuclease nsp14, ... | Authors: | Newman, J.A, Imprachim, N, Yosaatmadja, Y, Gileadi, O. | Deposit date: | 2021-12-14 | Release date: | 2022-02-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development. Nucleic Acids Res., 51, 2023
|
|
7SC1
 
 | |
7TLA
 
 | |
7TLB
 
 | |
7TLC
 
 | |
7TLD
 
 | |
7TLY
 
 | |
7TM0
 
 | |
7TN0
 
 | SARS-CoV-2 Omicron RBD in complex with human ACE2 and S304 Fab and S309 Fab | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | McCallum, M, Czudnochowski, N, Nix, J.C, Croll, T.I, SSGCID, Dillen, J.R, Snell, G, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2022-01-20 | Release date: | 2022-02-02 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. Science, 375, 2022
|
|
7TOB
 
 | Crystal structure of the SARS-CoV-2 Omicron main protease (Mpro) in complex with inhibitor GC376 | Descriptor: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER | Authors: | Sacco, M.D, Wang, J, Chen, Y. | Deposit date: | 2022-01-24 | Release date: | 2022-02-02 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The P132H mutation in the main protease of Omicron SARS-CoV-2 decreases thermal stability without compromising catalysis or small-molecule drug inhibition. Cell Res., 32, 2022
|
|
7WCR
 
 | RBD-1 of SARS-CoV-2 Beta spike in complex with S5D2 Fab | Descriptor: | Heavy chain of S5D2 Fab, Light chain of S5D2 Fab, Spike glycoprotein | Authors: | Wang, Y.F, Cong, Y. | Deposit date: | 2021-12-20 | Release date: | 2022-02-02 | Last modified: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein. Emerg Microbes Infect, 11, 2022
|
|
7WCZ
 
 | SARS-CoV-2 Beta spike in complex with one S5D2 Fab | Descriptor: | Heavy chain of S5D2 Fab, Light chain of S5D2 Fab, Spike glycoprotein | Authors: | Wang, Y.F, Cong, Y. | Deposit date: | 2021-12-20 | Release date: | 2022-02-02 | Last modified: | 2024-11-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein. Emerg Microbes Infect, 11, 2022
|
|
7WD0
 
 | SARS-CoV-2 Beta spike in complex with two S5D2 Fabs | Descriptor: | Heavy chain of S5D2 Fab, Light chain of S5D2 Fab, Spike glycoprotein | Authors: | Wang, Y.F, Cong, Y. | Deposit date: | 2021-12-20 | Release date: | 2022-02-02 | Last modified: | 2024-11-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein. Emerg Microbes Infect, 11, 2022
|
|
7WD7
 
 | SARS-CoV-2 Beta spike in complex with three S5D2 Fabs | Descriptor: | Heavy chain of S5D2 Fab, Light chain of S5D2 Fab, Spike glycoprotein | Authors: | Wang, Y.F, Cong, Y. | Deposit date: | 2021-12-21 | Release date: | 2022-02-02 | Last modified: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein. Emerg Microbes Infect, 11, 2022
|
|
7WD8
 
 | SARS-CoV-2 Beta spike SD1 in complex with S3H3 Fab | Descriptor: | Heavy chain of S3H3 Fab, Light chain of S3H3 Fab, Spike glycoprotein | Authors: | Wang, Y.F, Cong, Y. | Deposit date: | 2021-12-21 | Release date: | 2022-02-02 | Last modified: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein. Emerg Microbes Infect, 11, 2022
|
|
7WD9
 
 | SARS-CoV-2 Beta spike in complex with three S3H3 Fabs | Descriptor: | Heavy chain of S3H3 Fab, Light chain of S3H3 Fab, Spike glycoprotein | Authors: | Wang, Y.F, Cong, Y. | Deposit date: | 2021-12-21 | Release date: | 2022-02-02 | Last modified: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein. Emerg Microbes Infect, 11, 2022
|
|
7WDF
 
 | SARS-CoV-2 Beta spike in complex with two S3H3 Fabs | Descriptor: | Heavy chain of S3H3 Fab, Light chain of S3H3 Fab, Spike glycoprotein | Authors: | Wang, Y.F, Cong, Y. | Deposit date: | 2021-12-21 | Release date: | 2022-02-02 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein. Emerg Microbes Infect, 11, 2022
|
|
7WK4
 
 | |
7WK5
 
 | Cryo-EM structure of Omicron S-ACE2, C2 state | Descriptor: | Angiotensin-converting enzyme 2, Spike glycoprotein | Authors: | Han, W.Y, Wang, Y.F. | Deposit date: | 2022-01-08 | Release date: | 2022-02-02 | Last modified: | 2024-11-20 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Molecular basis of SARS-CoV-2 Omicron variant receptor engagement and antibody evasion and neutralization Biorxiv, 2022
|
|