7NLL

SARS-CoV-2 Spike RBD (dimer) in complex with two Fu2 nanobodies

Summary for 7NLL

Entry DOI	10.2210/pdb7nll/pdb
EMDB information	12465
Descriptor	Spike protein S1, Nanobody Fu2, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	nanobody, spike, complex, dimer, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	4
Total formula weight	83448.60
Authors	Das, H.,Hallberg, B.M. (deposition date: 2021-02-22, release date: 2022-02-02, Last modification date: 2023-09-27)
Primary citation	Hanke, L.,Das, H.,Sheward, D.J.,Perez Vidakovics, L.,Urgard, E.,Moliner-Morro, A.,Kim, C.,Karl, V.,Pankow, A.,Smith, N.L.,Porebski, B.,Fernandez-Capetillo, O.,Sezgin, E.,Pedersen, G.K.,Coquet, J.M.,Hallberg, B.M.,Murrell, B.,McInerney, G.M. A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo. Nat Commun, 13:155-155, 2022 Cited by PubMed: 35013189 DOI: 10.1038/s41467-021-27610-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.89 Å)

Structure validation