신종 코로나바이러스 특집 콘텐츠

이 페이지는 다른 언어로도 제공됩니다: English 日本語简体中文繁體中文

코로나 바이러스, 2020. David S. Goodsell @ RCSB PDB에 의한 오리지널 일러스트를 수정

신종 코로나바이러스 감염증 (Novel Coronavirus disease 2019:COVID-19)의 확산이 세계적으로 매우 큰 문제가 되고 있습니다. 시급히 새로운 바이러스（Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2）를 이해하고 효과적인 약을 개발하기 위해, 신속하게 구조 생물학 연구가 시작되고 있습니다. PDBj는 사용자의 편의를 도모하기 위해 신종 코로나바이러스의 특집 페이지를 제공하고 있습니다. 매주 수요일에 최신 항목이 추가됩니다.

바이러스 단백질에 관한 해설기사는 아래의 「이달의 분자」 페이지를 참조하십시오.

「전체 엔트리」 탭에는, 모든 PDB ID가 포함되어 있습니다. 이용자가 전체의 독립된 엔트리를 검색하고 싶을 때 사용하실 수 있으며, 동일 저자에 의한 그룹등록의 엔트리도 전부 구별되어 있습니다. 「대표구조」 탭에는, 분해능이 가장 높은 대표구조만을 표지하고 있습니다. 아미노산 서열이 100 % 일치하는 PDB 엔트리의 경우, 다른 리간드를 포함하여도 대표구조에는 제외됩니다. 「최신 엔트리」 탭은, 이번주 공개된 가장 최근의 엔트리 입니다.

Created: 2020-09-03 (last edited: more than 1 year ago)

전체 엔트리 (4459)대표구조 (1984)최신 엔트리 (16)

5SSP

PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5459166285 - (R,R) and (S,S) isomers
Descriptor:	(1R,2R)-4-hydroxy-1-[(1H-indole-5-carbonyl)amino]-2,3-dihydro-1H-indene-2-carboxylic acid, (1S,2S)-4-hydroxy-1-[(1H-indole-5-carbonyl)amino]-2,3-dihydro-1H-indene-2-carboxylic acid, Non-structural protein 3
Authors:	Correy, G.J, Fraser, J.S.
Deposit date:	2022-06-09
Release date:	2022-07-06
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.15 Å)
Cite:	Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023

5SSQ

PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5459166291
Descriptor:	3-{[(1H-benzimidazole-5-carbonyl)amino]methyl}-1H-indole-2-carboxylic acid, Non-structural protein 3
Authors:	Correy, G.J, Fraser, J.S.
Deposit date:	2022-06-09
Release date:	2022-07-06
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.15 Å)
Cite:	Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023

5SSR

PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5459166300
Descriptor:	3-{[(2-hydroxy-1H-benzimidazole-5-carbonyl)amino]methyl}-1H-indole-2-carboxylic acid, Non-structural protein 3
Authors:	Correy, G.J, Fraser, J.S.
Deposit date:	2022-06-09
Release date:	2022-07-06
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.15 Å)
Cite:	Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023

7TUQ

Crystal structure of BRD4 bromodomain 1 in complex with monoacetylated SARS-CoV-2 E
Descriptor:	Bromodomain-containing protein 4, Envelope small membrane protein
Authors:	Vann, K.R, Kutateladze, T.G.
Deposit date:	2022-02-03
Release date:	2022-07-06
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.68 Å)
Cite:	Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection. Structure, 30, 2022

7TV0

Crystal structure of BRD4 bromodomain 1 in complex with dual-acetylated SARS-CoV-2 E
Descriptor:	Bromodomain-containing protein 4, Envelope small membrane protein
Authors:	Vann, K.R, Holt, T.A, Kutateladze, T.G.
Deposit date:	2022-02-03
Release date:	2022-07-06
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection. Structure, 30, 2022

7VBE

1.6 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 5.0
Descriptor:	Nucleoprotein
Authors:	Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
Deposit date:	2021-08-31
Release date:	2022-07-06
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (1.59 Å)
Cite:	1.6 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 5.0 To Be Published

7VBF

1.3 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 8.5
Descriptor:	Nucleoprotein
Authors:	Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
Deposit date:	2021-08-31
Release date:	2022-07-06
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (1.3 Å)
Cite:	1.3 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 8.5 To Be Published

7X1M

The complex structure of Omicron BA.1 RBD with BD604, S309,and S304
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD-604 Fab heavy chain, BD-604 Fab light chain, ...
Authors:	Huang, M, Xie, Y.F, Qi, J.X.
Deposit date:	2022-02-24
Release date:	2022-07-06
Last modified:	2023-07-19
Method:	ELECTRON MICROSCOPY (2.74 Å)
Cite:	Atlas of currently available human neutralizing antibodies against SARS-CoV-2 and escape by Omicron sub-variants BA.1/BA.1.1/BA.2/BA.3. Immunity, 55, 2022

7X6J

SARS-CoV-2 3CL protease (3CLpro) in complex with compound 3af
Descriptor:	3C-like proteinase, quinoline-2-carboxylic acid
Authors:	Su, H, Nie, T, Xie, H, Li, Z.W, Li, M.J, Xu, Y.
Deposit date:	2022-03-07
Release date:	2022-07-06
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure-Activity Relationships, Antiviral Activity, and X-ray Structure Determination. J.Med.Chem., 65, 2022

7X6K

SARS-CoV-2 3CL protease (3CLpro) in complex with compound 3w
Descriptor:	1H-indole-2-carbaldehyde, 3C-like proteinase
Authors:	Su, H, Nie, T, Xie, H, Li, Z.W, Li, M.J, Xu, Y.
Deposit date:	2022-03-07
Release date:	2022-07-06
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.34 Å)
Cite:	Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure-Activity Relationships, Antiviral Activity, and X-ray Structure Determination. J.Med.Chem., 65, 2022

7XAZ

Crystal structure of Omicron BA.1.1 RBD complexed with hACE2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:	Liao, H, Meng, Y, Li, W.
Deposit date:	2022-03-19
Release date:	2022-07-06
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1. Cell, 185, 2022

7XB0

Crystal structure of Omicron BA.2 RBD complexed with hACE2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:	Li, L, Liao, H, Meng, Y, Li, W.
Deposit date:	2022-03-19
Release date:	2022-07-06
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1. Cell, 185, 2022

7XB1

Crystal structure of Omicron BA.3 RBD complexed with hACE2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:	Li, W, Meng, Y, Liao, H.
Deposit date:	2022-03-19
Release date:	2022-07-06
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1. Cell, 185, 2022

7Y42

Cryo-EM structure of the SARS-CoV-2 spike glycoprotein in complex with all-trans retinoic acid
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, RETINOIC ACID, Spike glycoprotein
Authors:	Xiang, Y, Wang, L.
Deposit date:	2022-06-13
Release date:	2022-07-06
Last modified:	2022-09-14
Method:	ELECTRON MICROSCOPY (3.45 Å)
Cite:	A Retinol Derivative Inhibits SARS-CoV-2 Infection by Interrupting Spike-Mediated Cellular Entry. Mbio, 13, 2022

8CWU

Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing nanobody 1-21
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, VHH 1-21
Authors:	Liu, H, Wilson, I.A.
Deposit date:	2022-05-19
Release date:	2022-07-06
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.71 Å)
Cite:	Superimmunity by pan-sarbecovirus nanobodies. Cell Rep, 39, 2022

8CWV

Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing nanobody 2-31 and a human antibody CC12.1 Fab
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 Fab heavy chain, CC12.1 Fab light chain, ...
Authors:	Liu, H, Wilson, I.A.
Deposit date:	2022-05-19
Release date:	2022-07-06
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.51 Å)
Cite:	Superimmunity by pan-sarbecovirus nanobodies. Cell Rep, 39, 2022

8CXN

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-57
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, pan-sarbecovirus nanobody 2-57
Authors:	Huang, W, Taylor, D.
Deposit date:	2022-05-22
Release date:	2022-07-06
Last modified:	2022-07-13
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Superimmunity by pan-sarbecovirus nanobodies. Cell Rep, 39, 2022

8CXQ

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 1-22
Descriptor:	Spike glycoprotein, pan-sarbecovirus nanobody 1-22
Authors:	Huang, W, Taylor, D.
Deposit date:	2022-05-22
Release date:	2022-07-06
Last modified:	2022-07-13
Method:	ELECTRON MICROSCOPY (2.3 Å)
Cite:	Superimmunity by pan-sarbecovirus nanobodies. Cell Rep, 39, 2022

8CY6

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-65
Descriptor:	Spike glycoprotein, pan-sarbecovirus nanobody 2-65
Authors:	Huang, W, Taylor, D.
Deposit date:	2022-05-23
Release date:	2022-07-06
Last modified:	2022-07-13
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Superimmunity by pan-sarbecovirus nanobodies. Cell Rep, 39, 2022

8CY7

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-34
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Huang, W, Taylor, D.
Deposit date:	2022-05-23
Release date:	2022-07-06
Last modified:	2022-07-13
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Superimmunity by pan-sarbecovirus nanobodies. Cell Rep, 39, 2022

8CY9

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 1-23
Descriptor:	Spike glycoprotein, pan-sarbecovirus nanobody 1-23
Authors:	Huang, W, Taylor, D.
Deposit date:	2022-05-23
Release date:	2022-07-06
Last modified:	2022-07-13
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Superimmunity by pan-sarbecovirus nanobodies. Cell Rep, 39, 2022

8CYA

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-67
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Huang, W, Taylor, D.
Deposit date:	2022-05-23
Release date:	2022-07-06
Last modified:	2022-07-13
Method:	ELECTRON MICROSCOPY (2.7 Å)
Cite:	Superimmunity by pan-sarbecovirus nanobodies. Cell Rep, 39, 2022

8CYB

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 1-8
Descriptor:	1-deoxy-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Huang, W, Taylor, D.
Deposit date:	2022-05-23
Release date:	2022-07-06
Last modified:	2022-07-13
Method:	ELECTRON MICROSCOPY (2.7 Å)
Cite:	Superimmunity by pan-sarbecovirus nanobodies. Cell Rep, 39, 2022

8CYC

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-34
Descriptor:	Spike glycoprotein, pan-sarbecovirus nanobody 2-34
Authors:	Huang, W, Taylor, D.
Deposit date:	2022-05-23
Release date:	2022-07-06
Last modified:	2022-07-13
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Superimmunity by pan-sarbecovirus nanobodies. Cell Rep, 39, 2022

8CYD

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-45
Descriptor:	Spike glycoprotein, pan-sarbecovirus nanobody 2-45
Authors:	Huang, W, Taylor, D.
Deposit date:	2022-05-23
Release date:	2022-07-06
Last modified:	2022-07-13
Method:	ELECTRON MICROSCOPY (2.6 Å)
Cite:	Superimmunity by pan-sarbecovirus nanobodies. Cell Rep, 39, 2022

<88 89 90 91 92 93 949596 97 98 99 100 101 102 103 >

Total results:	4459
Displayed results:	25
Sorted by:	Release date (from oldest)