- PDB-5mv4: ACC1 Fab fragment in complex with citrullinated CII616-639 epitop... -
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基本情報
登録情報
データベース: PDB / ID: 5mv4
タイトル
ACC1 Fab fragment in complex with citrullinated CII616-639 epitope of collagen type II (ptm23)
要素
ACC1 antibody Fab fragment, heavy chain
ACC1 antibody Fab fragment, light chain
synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639
キーワード
IMMUNE SYSTEM / anti-citrullinated protein antibody (ACPA) Fab fragment collagen type II citrullinated C1 epitope
機能・相同性
機能・相同性情報
Non-integrin membrane-ECM interactions / Extracellular matrix organization / NCAM1 interactions / Signaling by PDGF / Collagen biosynthesis and modifying enzymes / Collagen chain trimerization / collagen type II trimer / collagen type XI trimer / anterior head development / Collagen degradation ...Non-integrin membrane-ECM interactions / Extracellular matrix organization / NCAM1 interactions / Signaling by PDGF / Collagen biosynthesis and modifying enzymes / Collagen chain trimerization / collagen type II trimer / collagen type XI trimer / anterior head development / Collagen degradation / MET activates PTK2 signaling / Assembly of collagen fibrils and other multimeric structures / embryonic skeletal joint morphogenesis / otic vesicle development / ECM proteoglycans / Collagen chain trimerization / proteoglycan metabolic process / platelet-derived growth factor binding / extracellular matrix structural constituent conferring tensile strength / Integrin cell surface interactions / Extracellular matrix organization / notochord development / limb bud formation / cartilage development involved in endochondral bone morphogenesis / Collagen biosynthesis and modifying enzymes / limb morphogenesis / tissue homeostasis / MHC class II protein binding / cellular response to BMP stimulus / Signaling by PDGF / endochondral ossification / collagen trimer / NCAM1 interactions / collagen fibril organization / cartilage development / skeletal system morphogenesis / proteoglycan binding / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / Assembly of collagen fibrils and other multimeric structures / MET activates PTK2 signaling / inner ear morphogenesis / cartilage condensation / roof of mouth development / inner ear development / Collagen degradation / Non-integrin membrane-ECM interactions / basement membrane / negative regulation of extrinsic apoptotic signaling pathway in absence of ligand / ECM proteoglycans / Integrin cell surface interactions / chondrocyte differentiation / heart morphogenesis / extrinsic apoptotic signaling pathway in absence of ligand / visual perception / extracellular matrix / ossification / skeletal system development / central nervous system development / sensory perception of sound / bone development / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / regulation of gene expression / collagen-containing extracellular matrix / endoplasmic reticulum lumen / protein homodimerization activity / extracellular space / extracellular region / identical protein binding / metal ion binding / cytoplasm 類似検索 - 分子機能
A: ACC1 antibody Fab fragment, heavy chain B: ACC1 antibody Fab fragment, light chain X: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 C: ACC1 antibody Fab fragment, heavy chain D: ACC1 antibody Fab fragment, light chain E: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 F: ACC1 antibody Fab fragment, heavy chain G: ACC1 antibody Fab fragment, light chain H: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 I: ACC1 antibody Fab fragment, heavy chain J: ACC1 antibody Fab fragment, light chain K: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 L: ACC1 antibody Fab fragment, heavy chain M: ACC1 antibody Fab fragment, light chain N: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 O: ACC1 antibody Fab fragment, heavy chain P: ACC1 antibody Fab fragment, light chain Q: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 R: ACC1 antibody Fab fragment, heavy chain S: ACC1 antibody Fab fragment, light chain T: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 U: ACC1 antibody Fab fragment, heavy chain V: ACC1 antibody Fab fragment, light chain W: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 ヘテロ分子
A: ACC1 antibody Fab fragment, heavy chain B: ACC1 antibody Fab fragment, light chain X: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 ヘテロ分子
C: ACC1 antibody Fab fragment, heavy chain D: ACC1 antibody Fab fragment, light chain E: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 ヘテロ分子
F: ACC1 antibody Fab fragment, heavy chain G: ACC1 antibody Fab fragment, light chain H: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 ヘテロ分子
I: ACC1 antibody Fab fragment, heavy chain J: ACC1 antibody Fab fragment, light chain K: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 ヘテロ分子
L: ACC1 antibody Fab fragment, heavy chain M: ACC1 antibody Fab fragment, light chain N: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 ヘテロ分子
O: ACC1 antibody Fab fragment, heavy chain P: ACC1 antibody Fab fragment, light chain Q: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 ヘテロ分子
R: ACC1 antibody Fab fragment, heavy chain S: ACC1 antibody Fab fragment, light chain T: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 ヘテロ分子
U: ACC1 antibody Fab fragment, heavy chain V: ACC1 antibody Fab fragment, light chain W: synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639 ヘテロ分子