Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Development and characterization of novel indazole-based PPAR-gamma partial agonists
Journal, issue, pages	To Be Published
Publish date	Aug 12, 2024 (structure data deposition date)
Authors	Koops, A.A. / Oerlemans, G.J.M. / Brunsveld, L.
External links	Search PubMed
Methods	X-ray diffraction
Resolution	1.9 - 2.55 Å
Structure data	PDB-9gfu: Human PPAR-gamma ligand binding domain in complex with AKGO172 Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-9gvp: Human PPAR-gamma ligand binding domain in complex with WG115 Method: X-RAY DIFFRACTION / Resolution: 2.05 Å PDB-9gvs: Human PPAR-gamma ligand binding domain in complex with AK176_C Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-9gw3: Human PPAR-gamma ligand binding domain in complex with LW56 Method: X-RAY DIFFRACTION / Resolution: 2 Å PDB-9gw4: Human PPAR-gamma ligand binding domain in complex with LW78 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-9gw7: Human PPAR-gamma ligand binding domain in complex with LW76 Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-9gw8: Human PPAR-gamma ligand binding domain in complex with LW75 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-9gwb: Human PPAR-gamma ligand binding domain in complex with LW69 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-9gwc: Human PPAR-gamma ligand binding domain in complex with LW99 Method: X-RAY DIFFRACTION / Resolution: 2 Å PDB-9gwe: Human PPAR-gamma ligand binding domain in complex with LW87 Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-9gwf: Human PPAR-gamma ligand binding domain in complex with LW100 Method: X-RAY DIFFRACTION / Resolution: 2.4 Å PDB-9gwh: Human PPAR-gamma ligand binding domain in complex with LW77 Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-9gwi: Human PPAR-gamma ligand binding domain in complex with LW23 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-9gwk: Human PPAR-gamma ligand binding domain in complex with AKGO6A Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-9gwl: Human PPAR-gamma ligand binding domain in complex with AKGO157 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-9gwm: Human PPAR-gamma ligand binding domain in complex with AKGO108 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-9gwn: Human PPAR-gamma ligand binding domain in complex with LW30 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-9gwp: Human PPAR-gamma ligand binding domain in complex with MRL-871 with two distinct binding modes Method: X-RAY DIFFRACTION / Resolution: 2.55 Å PDB-9gwq: Human PPAR-gamma ligand binding domain in complex with AKGO6D Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-9gwr: Human PPAR-gamma ligand binding domain in complex with AKGO10 Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-9gws: Human PPAR-gamma ligand binding domain in complex with AKGO8 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-9gwx: Human PPAR-gamma ligand binding domain in complex with AKGO141 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-9gwy: Human PPAR-gamma ligand binding domain in complex with AKGO78 Method: X-RAY DIFFRACTION / Resolution: 2.09 Å PDB-9gx0: Human PPAR-gamma ligand binding domain in complex with AKGO79 Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-9gx1: Human PPAR-gamma ligand binding domain in complex with AKGO80 Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-9gx2: Human PPAR-gamma ligand binding domain in complex with AKGO82 Method: X-RAY DIFFRACTION / Resolution: 2.35 Å PDB-9gx3: Human PPAR-gamma ligand binding domain in complex with AKGO12 Method: X-RAY DIFFRACTION / Resolution: 1.9 Å PDB-9gx4: Human PPAR-gamma ligand binding domain in complex with AKGO156 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-9gx5: Human PPAR-gamma ligand binding domain in complex with AKGO173 Method: X-RAY DIFFRACTION / Resolution: 2.45 Å PDB-9gx6: Human PPAR-gamma ligand binding domain in complex with AKGO166 Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-9gx7: Human PPAR-gamma ligand binding domain in complex with WG17 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-9gxd: Human PPAR-gamma ligand binding domain in complex with AKGO27 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å
Chemicals	PDB-1ik6: 3D structure of the E1beta subunit of pyruvate dehydrogenase from the archeon Pyrobaculum aerophilum ChemComp-HOH: WATER PDB-1ipp: HOMING ENDONUCLEASE/DNA COMPLEX PDB-1ipr: Unknown entry PDB-1ipw: INORGANIC PYROPHOSPHATASE FROM ESCHERICHIA COLI WITH THREE MAGNESIUM IONS PDB-1ips: ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (MANGANESE COMPLEX) PDB-1ipu: Unknown entry PDB-1irg: INTERFERON REGULATORY FACTOR-2 DNA BINDING DOMAIN, NMR, 20 STRUCTURES PDB-1ipz: Unknown entry PDB-1ipx: Unknown entry PDB-1ipv: Unknown entry PDB-1ipt: Unknown entry PDB-1ip0: NMR STRUCTURE OF HUMAN BETACELLULIN-2 PDB-1ipy: Unknown entry PDB-1ip9: SOLUTION STRUCTURE OF THE PB1 DOMAIN OF BEM1P PDB-1ip7: G129A HUMAN LYSOZYME PDB-1ip6: G127A HUMAN LYSOZYME PDB-1ip4: G72A HUMAN LYSOZYME ChemComp-4F1: 4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-1H-indazol-3-yl}benzoic acid PDB-1iqa: CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MOUSE RANK LIGAND PDB-1ip3: G68A HUMAN LYSOZYME PDB-1iqb: Crystal Structure of Urtica dioica Agglutinin Isolectin I PDB-1ip8: Unknown entry PDB-1iqd: Human Factor VIII C2 Domain complexed to human monoclonal BO2C11 Fab. PDB-1iqg: Human coagulation factor Xa in complex with M55159 PDB-1iqi: Human coagulation factor Xa in complex with M55125 PDB-1ip5: G105A HUMAN LYSOZYME PDB-1iqe: Human coagulation factor Xa in complex with M55590 PDB-1iqc: Crystal structure of Di-Heme Peroxidase from Nitrosomonas europaea PDB-1iqj: Human coagulation factor Xa in complex with M55124 PDB-1iql: Human coagulation factor Xa in complex with M54476 PDB-1iqh: Human coagulation factor Xa in complex with M55143 PDB-1iqf: Human coagulation factor Xa in complex with M55165
Source	homo sapiens (human)
Keywords	TRANSCRIPTION / PPAR / PPAR gamma / PPARg / peroxisome proliferator-activated receptor gamma / nuclear receptor / transcription factor / partial agonist / agonist