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TitleDevelopment and characterization of novel indazole-based PPAR-gamma partial agonists
Journal, issue, pagesTo Be Published
Publish dateAug 12, 2024 (structure data deposition date)
AuthorsKoops, A.A. / Oerlemans, G.J.M. / Brunsveld, L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-9gfu:
Human PPAR-gamma ligand binding domain in complex with AKGO172
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

PDB-1ik6:
3D structure of the E1beta subunit of pyruvate dehydrogenase from the archeon Pyrobaculum aerophilum

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / PPAR / PPAR gamma / PPARg / peroxisome proliferator-activated receptor gamma / nuclear receptor / transcription factor / partial agonist / agonist

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