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Showing 1 - 50 of 128 items for (author: kirk & s)

EMDB-46597: 
Human Sec61 complex inhibited by KZR-261
Method: single particle / : Park E, Wang L

EMDB-52520: 
Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity
Method: single particle / : Shahid R, Paavilainen VO

PDB-9hz5: 
Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity
Method: single particle / : Shahid R, Paavilainen VO

EMDB-46598: 
Human-yeast chimeric Sec complex bound to KZR-261 inhibitor
Method: single particle / : Park E, Wang L

EMDB-48457: 
Preclinical and clinical evaluation of a novel TRPA1 antagonist LY3526318
Method: single particle / : Nie S

PDB-9moe: 
Preclinical and clinical evaluation of a novel TRPA1 antagonist LY3526318
Method: single particle / : Nie S

EMDB-48083: 
Import stalled PINK1 TOM complex
Method: single particle / : Kirk NS, Glukhova A, Callegari S, Komander D

EMDB-48084: 
Import stalled PINK1 TOM complex, symmetry expanded
Method: single particle / : Kirk NS, Glukhova A, Callegari S, Komander D

EMDB-48085: 
Import stalled PINK1 TOM complex, extended TOM20 helix class
Method: single particle / : Kirk NS, Glukhova A, Callegari S, Komander D

PDB-9eih: 
Import stalled PINK1 TOM complex
Method: single particle / : Kirk NS, Glukhova A, Callegari S, Komander D

PDB-9eii: 
Import stalled PINK1 TOM complex, symmetry expanded
Method: single particle / : Kirk NS, Glukhova A, Callegari S, Komander D

PDB-9eij: 
Import stalled PINK1 TOM complex, extended TOM20 helix class
Method: single particle / : Kirk NS, Glukhova A, Callegari S, Komander D

EMDB-51318: 
Structure of the HrpA-bound E. coli disome, Class I
Method: single particle / : Esser HF, Berninghausen O, Becker T, Beckmann R

EMDB-51340: 
Structure of the HrpA-bound E. coli disome, Class II
Method: single particle / : Esser HF, Berninghausen O, Becker T, Beckmann R

PDB-9gft: 
Structure of the HrpA-bound E. coli disome, Class I
Method: single particle / : Esser HF, Berninghausen O, Becker T, Beckmann R

PDB-9ggr: 
Structure of the HrpA-bound E. coli disome, Class II
Method: single particle / : Esser HF, Berninghausen O, Becker T, Beckmann R

EMDB-16868: 
Nucleocapsid protein Sars-Cov2, refined map
Method: single particle / : Farci D, Piano D

EMDB-19638: 
YlmH bound to PtRNA-50S
Method: single particle / : Paternoga H, Dimitrova-Paternoga L, Wilson DN

EMDB-19641: 
YlmH bound to stalled 50S subunits with RqcH and PtRNA
Method: single particle / : Paternoga H, Wilson DN

PDB-8s1p: 
YlmH bound to PtRNA-50S
Method: single particle / : Paternoga H, Dimitrova-Paternoga L, Wilson DN

PDB-8s1u: 
YlmH bound to stalled 50S subunits with RqcH and PtRNA
Method: single particle / : Paternoga H, Wilson DN

EMDB-17430: 
Nucleocapsid protein Sars-Cov2
Method: single particle / : Farci D, Piano D, Graca AT

EMDB-43753: 
Yeast U1 snRNP with humanized U1C Zinc-Finger domain
Method: single particle / : Shi SS, Kuang ZL, Zhao R

PDB-8w2o: 
Yeast U1 snRNP with humanized U1C Zinc-Finger domain
Method: single particle / : Shi SS, Kuang ZL, Zhao R

EMDB-18207: 
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide, Glacios map
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-18230: 
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-18915: 
Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

PDB-8q7r: 
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

PDB-8r5h: 
Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-42804: 
Structure of nucleotide-free Pediculus humanus (Ph) PINK1 dimer
Method: single particle / : Gan ZY, Kirk NS, Leis A, Komander D

EMDB-42806: 
Structure of AMP-PNP-bound Pediculus humanus (Ph) PINK1 dimer
Method: single particle / : Gan ZY, Kirk NS, Leis A, Komander D

EMDB-42807: 
Structure of ADP-bound and phosphorylated Pediculus humanus (Ph) PINK1 dimer
Method: single particle / : Gan ZY, Kirk NS, Leis A, Komander D

PDB-8uyf: 
Structure of nucleotide-free Pediculus humanus (Ph) PINK1 dimer
Method: single particle / : Gan ZY, Kirk NS, Leis A, Komander D

PDB-8uyh: 
Structure of AMP-PNP-bound Pediculus humanus (Ph) PINK1 dimer
Method: single particle / : Gan ZY, Kirk NS, Leis A, Komander D

PDB-8uyi: 
Structure of ADP-bound and phosphorylated Pediculus humanus (Ph) PINK1 dimer
Method: single particle / : Gan ZY, Kirk NS, Leis A, Komander D

EMDB-18586: 
Cryo-EM reconstruction of crosslinked native Bacillus subtilis collided disome binding MutS2 SMR and KOW domains
Method: single particle / : Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR

EMDB-41138: 
CryoEM structure of MFRV-VILP bound to IGF1Rzip
Method: single particle / : Kirk NS

EMDB-18585: 
Cryo-EM reconstruction of Bacillus subtilis collided disome binding MutS2 SMR and KOW domains
Method: single particle / : Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR

EMDB-18901: 
Bacillus subtilis MutS2-collided disome complex (stalled 70S)
Method: single particle / : Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR

PDB-8r55: 
Bacillus subtilis MutS2-collided disome complex (collided 70S)
Method: single particle / : Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR

EMDB-18558: 
Bacillus subtilis MutS2-collided disome complex (stalled 70S)
Method: single particle / : Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR

PDB-8qpp: 
Bacillus subtilis MutS2-collided disome complex (stalled 70S)
Method: single particle / : Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR

EMDB-29764: 
Structure of the Plasmodium falciparum 20S proteasome complexed with inhibitor TDI-8304
Method: single particle / : Hsu HC, Li H

EMDB-29765: 
Structure of the Plasmodium falciparum 20S proteasome beta-6 A117D mutant complexed with inhibitor WLW-vs
Method: single particle / : Hsu HC, Li H

EMDB-42148: 
Structure of human constitutive 20S proteasome complexed with the inhibitor TDI-8304
Method: single particle / : Hsu HC, Li H

PDB-8g6e: 
Structure of the Plasmodium falciparum 20S proteasome complexed with inhibitor TDI-8304
Method: single particle / : Hsu HC, Li H

PDB-8g6f: 
Structure of the Plasmodium falciparum 20S proteasome beta-6 A117D mutant complexed with inhibitor WLW-vs
Method: single particle / : Hsu HC, Li H

PDB-8ud9: 
Structure of human constitutive 20S proteasome complexed with the inhibitor TDI-8304
Method: single particle / : Hsu HC, Li H
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