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Showing 1 - 50 of 129 items for author: a. & sen

PDB-5nd2:
Microtubule-bound MKLP2 motor domain in the presence of ADP
Method: single particle / : Atherton J, Yu IM, Cook A, Muretta JM, Joseph AP, Major J, Sourigues Y, Clause J, Topf M, Rosenfeld SS, Houdusse A, Moores CA

PDB-5nd3:
Microtubule-bound MKLP2 motor domain in the with no nucleotide
Method: single particle / : Atherton J, Yu IM, Cook A, Muretta JM, Joseph AP, Major J, Sourigues Y, Clause J, Topf M, Rosenfeld SS, Houdusse A, Moores CA

PDB-5nd4:
Microtubule-bound MKLP2 motor domain in the presence of ADP.AlFx
Method: single particle / : Atherton J, Yu IM, Cook A, Muretta JM, Joseph AP, Major J, Sourigues Y, Clause J, Topf M, Rosenfeld SS, Houdusse A, Moores CA

PDB-5nd7:
Microtubule-bound MKLP2 motor domain in the presence of AMPPNP
Method: single particle / : Atherton J, Yu IM, Cook A, Muretta JM, Joseph AP, Major J, Sourigues Y, Clause J, Topf M, Rosenfeld SS, Houdusse A, Moores CA

PDB-5w9h:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9i:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9j:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9k:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9l:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9m:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9n:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9o:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9p:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5vn3:
Cryo-EM model of B41 SOSIP.664 in complex with soluble CD4 (D1-D2) and fragment antigen binding variable domain of 17b
Method: single particle / : Ozorowski G, Pallesen J, Ward AB

PDB-5vn8:
Cryo-EM model of B41 SOSIP.664 in complex with fragment antigen binding variable domain of b12
Method: single particle / : Ozorowski G, Pallesen J, Ward AB, Cottrell CA

PDB-5mdx:
Cryo-EM structure of the PSII supercomplex from Arabidopsis thaliana
Method: single particle / : van Bezouwen LS, Caffarri S, Kale RS, Kouril R, Thunnissen AMWH, Oostergetel GT, Boekema EJ

PDB-5urw:
Structure of the extended type VI secretion system sheath in Myxococcus xanthus
Method: subtomogram averaging / : Chang YW, Rettberg LA, Jensen GJ

PDB-5urx:
Structure of the contracted type VI secretion system sheath in Myxococcus xanthus
Method: subtomogram averaging / : Chang YW, Rettberg LA, Jensen GJ

PDB-5nms:
Hsp21 dodecamer, structural model based on cryo-EM and homology modelling
Method: single particle / : Rutsdottir G, Harmark J, Koeck PJB, Hebert H, Soderberg CAG, Emanuelsson C

PDB-5ll6:
Structure of the 40S ABCE1 post-splitting complex in ribosome recycling and translation initiation
Method: single particle / : Heuer A, Gerovac M, Schmidt C, Trowitzsch S, Preis A, Koetter P, Berninghausen O, Becker T, Beckmann R, Tampe R

PDB-5umd:
Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine
Method: single particle / : Wong W, Bai XC, Brown A, Scheres S, Baum J

PDB-5tjt:
T5 bacteriophage major capsid protein - one PB8 hexon
Method: single particle / : Conway J, Huet A

PDB-5kep:
High resolution cryo-EM maps of Human Papillomavirus 16 reveal L2 location and heparin-induced conformational changes
Method: single particle / : Guan J, Bywaters SM, Brendle SA, Ashley RE, Makhov AM, Conway JF, Christensen ND, Hafenstein S

PDB-5keq:
High resolution cryo-EM maps of Human papillomavirus 16 reveal L2 location and heparin-induced conformational changes
Method: single particle / : Guan J, Bywaters SM, Brendle SA, Ashley RE, Makhov AM, Conway JF, Christensen ND, Hafenstein S

PDB-5mc6:
Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae
Method: single particle / : Schmidt C, Kowalinski E, Shanmuganathan V, Defenouillere Q, Braunger K, Heuer A, Pech M, Namane A, Berninghausen O, Fromont-Racine M, Jacquier A, Conti E, Becker T, Beckmann R

PDB-5knz:
Human Islet Amyloid Polypeptide Segment 19-SGNNFGAILSS-29 with Early Onset S20G Mutation Determined by MicroED
Method: electron crystallography / : Krotee PAL, Rodriguez JA, Sawaya MR, Cascio D, Shi D, Nannenga BL, Hattne J, Reyes FE, Gonen T, Eisenberg DS

PDB-5ko0:
Human Islet Amyloid Polypeptide Segment 15-FLVHSSNNFGA-25 Determined by MicroED
Method: electron crystallography / : Krotee PAL, Rodriguez JA, Sawaya MR, Cascio D, Shi D, Nannenga BL, Hattne J, Reyes FE, Gonen T, Eisenberg DS

PDB-5m5h:
RIBOSOME-BOUND YIDC INSERTASE
Method: single particle / : Kedrov A, Wickles S, Crevenna AH, van der Sluis E, Buschauer R, Berninghausen O, Lamb DC, Beckmann R

PDB-5fkx:
Structure of E.coli inducible lysine decarboxylase at active pH
Method: single particle / : Kandiah E, Carriel D, Perard J, Malet H, Bacia M, Liu K, Chan SWS, Houry WA, Ollagnier de Choudens S, Elsen S, Gutsche I

PDB-5fkz:
Structure of E.coli Constitutive lysine decarboxylase
Method: single particle / : Kandiah E, Carriel D, Perard J, Malet H, Bacia M, Liu K, Chan SWS, Houry WA, Ollagnier de Choudens S, Elsen S, Gutsche I

PDB-5fl2:
Revisited cryo-EM structure of Inducible lysine decarboxylase complexed with LARA domain of RavA ATPase
Method: single particle / : Kandiah E, Carriel D, Perard J, Malet H, Bacia M, Liu K, Chan SWS, Houry WA, Ollagnier de Choudens S, Elsen S, Gutsche I

PDB-5k2e:
Structure of NNQQNY from yeast prion Sup35 with zinc acetate determined by MicroED
Method: electron crystallography / : Rodriguez JA, Sawaya MR, Cascio D, Eisenberg DS

PDB-5k2f:
Structure of NNQQNY from yeast prion Sup35 with cadmium acetate determined by MicroED
Method: electron crystallography / : Rodriguez JA, Sawaya MR, Cascio D, Eisenberg DS

PDB-5k2g:
Structure of GNNQQNY from yeast prion Sup35 in space group P21 determined by MicroED
Method: electron crystallography / : Rodriguez JA, Sawaya MR, Cascio D, Eisenberg DS

PDB-5k2h:
Structure of GNNQQNY from yeast prion Sup35 in space group P212121 determined by MicroED
Method: electron crystallography / : Rodriguez JA, Sawaya MR, Cascio D, Eisenberg DS

PDB-5kel:
EBOV GP in complex with variable Fab domains of IgGs c2G4 and c13C6
Method: single particle / : Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe Jr JE, Andersen KG, Saphire EO, Ward AB

PDB-5kem:
EBOV sGP in complex with variable Fab domains of IgGs c13C6 and BDBV91
Method: single particle / : Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe Jr JE, Andersen KG, Saphire EO, Ward AB

PDB-5ken:
EBOV GP in complex with variable Fab domains of IgGs c4G7 and c13C6
Method: single particle / : Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe Jr JE, Andersen KG, Saphire EO, Ward AB

PDB-5ipi:
Structure of Adeno-associated virus type 2 VLP
Method: single particle / : Drouin LM, Lins B, Janssen ME, Bennet A, Chipman P, McKenna R, Chen W, Muzyczka N, Cardone G, Baker TS, Agbandje-McKenna M

PDB-5ipk:
Structure of the R432A variant of Adeno-associated virus type 2 VLP
Method: single particle / : Drouin LM, Lins B, Janssen ME, Bennet A, Chipman P, McKenna R, Chen W, Muzyczka N, Cardone G, Baker TS, Agbandje-McKenna M

PDB-5iz7:
Cryo-EM structure of thermally stable Zika virus strain H/PF/2013
Method: single particle / : Kostyuchenko VA, Zhang S, Fibriansah G, Lok SM

PDB-5hi9:
Structure of the full-length TRPV2 channel by cryo-electron microscopy
Method: single particle / : Huynh KW, Cohen MR, Jiansen J, Samanta A, Lodowski DT, Zhou ZH, Moiseenkova-Bell VY

PDB-3jc8:
Architectural model of the type IVa pilus machine in a piliated state
Method: electron tomography / : Chang YW, Rettberg LA, Jensen GJ

PDB-3jc9:
Architectural model of the type IVa pilus machine in a non-piliated state
Method: electron tomography / : Chang YW, Rettberg LA, Jensen GJ

PDB-5i08:
Prefusion structure of a human coronavirus spike protein
Method: single particle / : Kirchdoerfer RN, Cottrell CA, Wang N, Pallesen J, Yassine HM, Turner HL, Corbett KS, Graham BS, McLellan JS, Ward AB

PDB-3jba:
The U4 antibody epitope on human papillomavirus 16 identified by cryo-EM
Method: single particle / : Guan J, Bywaters SM, Brendle SA, Lee H, Ashley RE, Christensen ND, Hafenstein S

PDB-4znn:
MicroED structure of the segment, GVVHGVTTVA, from the A53T familial mutant of Parkinson's disease protein, alpha-synuclein residues 47-56
Method: electron crystallography / : Rodriguez JA, Ivanova M, Sawaya MR, Cascio D, Reyes F, Shi D, Johnson L, Guenther E, Sangwan S, Hattne J, Nannenga B, Brewster AS, Messerschmidt M, Boutet S, Sauter NK, Gonen T, Eisenberg DS

PDB-4ril:
Structure of the amyloid forming segment, GAVVTGVTAVA, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 68-78, determined by electron diffraction
Method: electron crystallography / : Rodriguez JA, Ivanova M, Sawaya MR, Cascio D, Reyes F, Shi D, Johnson L, Guenther E, Sangwan S, Hattne J, Nannenga B, Brewster AS, Messerschmidt M, Boutet S, Sauter NK, Gonen T, Eisenberg DS

PDB-5a9k:
Structural basis for DNA strand separation by a hexameric replicative helicase
Method: single particle / : Chaban Y, Stead JA, Ryzhenkova K, Whelan F, Lamber K, Antson F, Sanders CM, Orlova EV

PDB-4udf:
STRUCTURAL BASIS OF HUMAN PARECHOVIRUS NEUTRALIZATION BY HUMAN MONOCLONAL ANTIBODIES
Method: single particle / : Shakeel S, Westerhuis BM, Ora A, Koen G, Bakker AQ, Claassen Y, Beaumont T, Wolthers KC, Butcher SJ

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Oct 4, 2017. Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

  • Jacques Dubochet (University of Lausanne, Switzerland) is a pioneer of ice-embedding method of EM specimen (as known as cryo-EM), Most of 3DEM structures in EMDB and PDB are obtained using his method.
  • Joachim Frank (Columbia University, New York, USA) is a pioneer of single particle reconstruction, which is the most used reconstruction method for 3DEM structures in EMDB and EM entries in PDB. And also, he is a develper of Spider, which is one of the most famous software in this field, and is used for some EM Navigor data (e.g. map projection/slice images).
  • Richard Henderson (MRC Laboratory of Molecular Biology, Cambridge, UK) was determined the first biomolecule structure by EM. The first EM entry in PDB, PDB-1brd is determinedby him.

External links: The 2017 Nobel Prize in Chemistry - Press Release

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