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Showing 1 - 50 of 62 items for (author: locher & kp)

EMDB-19440:
Cryo-EM structure of human NTCP-Bulevirtide complex
Method: single particle / : Liu H, Zakrzewicz D, Nosol K, Irobalieva RN, Mukherjee S, Bang-Soerensen R, Goldmann N, Kunz S, Rossi L, Kossiakoff AA, Urban S, Glebe D, Geyer J, Locher KP

EMDB-17761:
Vanadate-trapped BSEP in nanodiscs
Method: single particle / : Liu H, Irobalieva RN, Kowal J, Ni D, Nosol K, Bang-Sorensen R, Lancien L, Stahlberg H, Stieger B, Locher KP

EMDB-17758:
Human bile salt export pump (BSEP) in complex with inhibitor GBM in nanodiscs
Method: single particle / : Liu H, Irobalieva RN, Kowal J, Ni D, Nosol K, Bang-Sorensen R, Lancien L, Stahlberg H, Stieger B, Locher KP

EMDB-17759:
Nucleotide-bound BSEP in nanodiscs
Method: single particle / : Liu H, Irobalieva RN, Kowal J, Ni D, Nosol K, Bang-Sorensen R, Lancien L, Stahlberg H, Stieger B, Locher KP

EMDB-17655:
Human OATP1B3
Method: single particle / : Ciuta AD, Nosol K, Kowal J, Mukherjee S, Ramirez AS, Stieger B, Kossiakoff AA, Locher KP

EMDB-17677:
Human OATP1B1
Method: single particle / : Ciuta AD, Nosol K, Kowal J, Mukherjee S, Ramirez AS, Stieger B, Kossiakoff AA, Locher KP

EMDB-17537:
Structure of 5D3-Fab and nanobody(Nb8)-bound ABCG2
Method: single particle / : Irobalieva RN, Manolaridis I, Jackson SM, Ni D, Pardon E, Stahlberg H, Steyaert J, Locher KP

EMDB-17543:
Structure of 5D3-Fab and nanobody(Nb17)-bound ABCG2
Method: single particle / : Irobalieva RN, Manolaridis I, Jackson SM, Ni D, Pardon E, Stahlberg H, Steyaert J, Locher KP

EMDB-17547:
Structure of 5D3-Fab and nanobody(Nb96)-bound ABCG2
Method: single particle / : Irobalieva RN, Manolaridis I, Jackson SM, Ni D, Pardon E, Stahlberg H, Steyaert J, Locher KP

EMDB-14779:
Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with acceptor peptide and bound to CMT2-Fab and anti-Fab nanobody
Method: single particle / : Bloch JS, Mukherjee S, Mao R, Irobalieva R, Kossiakoff AA, Goddard-Borger ED, Locher KP

EMDB-14780:
Cryo-EM structure of C-mannosyltransferase CeDPY19, in apo state, bound to CMT2-Fab and anti-Fab nanobody
Method: single particle / : Bloch JS, Mukherjee S, Irobalieva R, Kossiakoff AA, Goddard-Borger ED, Locher KP

EMDB-14781:
Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with Dol25-P-Man and bound to CMT2-Fab and anti-Fab nanobody
Method: single particle / : Bloch JS, Mukherjee S, Boilevin J, Irobalieva R, Darbre T, Reymond JL, Kossiakoff AA, Goddard-Borger ED, Locher KP

EMDB-14782:
Cryo-EM structure of C-mannosyltransferase CeDPY19, in ternary complex with Dol25-P-C-Man and acceptor peptide, bound to CMT2-Fab and anti-Fab nanobody
Method: single particle / : Bloch JS, Mao R, Mukherjee S, Boilevin J, Irobalieva R, Darbre T, Reymond JL, Kossiakoff AA, Goddard-Borger ED, Locher KP

EMDB-16069:
ABCG2 turnover-1 state with tariquidar bound
Method: single particle / : Yu Q, Kowal J, Tajkhorshid E, Locher KP

EMDB-16075:
ABCG2 turnover-2 state with tariquidar bound
Method: single particle / : Yu Q, Kowal J, Tajkhorshid E, Locher KP

EMDB-15419:
Structure of yeast oligosaccharylransferase complex with lipid-linked oligosaccharide bound
Method: single particle / : Ramirez AS, de Capitani M, Pesciullesi G, Kowal J, Bloch JS, Irobalieva RN, Aebi M, Reymond JL, Locher KP

EMDB-15420:
Structure of yeast oligosaccharylransferase complex with lipid-linked oligosaccharide and non-acceptor peptide bound
Method: single particle / : Ramirez AS, de Capitani M, Pesciullesi G, Kowal J, Bloch JS, Irobalieva RN, Aebi M, Reymond JL, Locher KP

EMDB-15421:
Structure of yeast oligosaccharylransferase complex with acceptor peptide bound
Method: single particle / : Ramirez AS, de Capitani M, Pesciullesi G, Kowal J, Bloch JS, Irobalieva RN, Aebi M, Reymond JL, Locher KP

EMDB-15024:
Structure of the human sodium/bile acid cotransporter (NTCP) in complex with Fab and nanobody
Method: single particle / : Liu H, Irobalieva RN, Bang-Sorensen R, Nosol K, Mukherjee S, Agrawal P, Stieger B, Kossiakoff AA, Locher KP

EMDB-12808:
Cryo-EM structure of yeast Ost6p containing oligosaccharyltransferase complex
Method: single particle / : Wild R, Neuhaus JD, Eyring J, Irobalieva RN, Kowal J, Lin CW, Locher KP, Aebi M

EMDB-12765:
Encequidar-bound human P-glycoprotein in complex with UIC2-Fab
Method: single particle / : Nosol K, Locher KP

EMDB-13118:
Cryo-EM structure of ABCG1 E242Q mutant with ATP and cholesteryl hemisuccinate bound
Method: single particle / : Skarda L, Kowal J, Locher KP

EMDB-13424:
Structure of Multidrug and Toxin Compound Extrusion (MATE) transporter NorM by NabFab-fiducial assisted cryo-EM
Method: single particle / : Bloch JS, Mukherjee S, Kowal J, Niederer M, Pardon E, Steyaert J, Kossiakoff AA, Locher KP

EMDB-13425:
Map of complex of Vibrio cholerae MATE transporter NorM, chimeric nanobody NorM-Nb17_4, NabFab, and anti-Fab nanobody with fulcrum in center of micelle
Method: single particle / : Bloch JS, Mukherjee S, Kowal J, Niederer M, Pardon E, Steyaert J, Kossiakoff AA, Locher KP

EMDB-13426:
Structure of homo-dimeric Staphylococcus capitis divalent metal ion transporter (DMT) by NabFab-fiducial assisted cryo-EM
Method: single particle / : Bloch JS, Mukherjee S, Kowal J, Kossiakoff AA, Locher KP

EMDB-13438:
Structure of Staphylococcus capitis divalent metal ion transporter (DMT) by NabFab-fiducial assisted cryo-EM
Method: single particle / : Bloch JS, Mukherjee S, Kowal J, Kossiakoff AA, Locher KP

EMDB-12365:
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (apo-inward-open conformation)
Method: single particle / : Nosol K, Locher KP

EMDB-12366:
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded conformation)
Method: single particle / : Nosol K, Locher KP

EMDB-12367:
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab (posaconazole-bound, inward-open conformation)
Method: single particle / : Nosol K, Locher KP

EMDB-12939:
ABCG2 E1S turnover-2 state
Method: single particle / : Ni D, Yu Q, Kowal J, Manolaridis I, Jackson SM, Stahlberg H, Locher KP

EMDB-12951:
ABCG2 topotecan turnover-1 state
Method: single particle / : Yu Q, Ni D, Kowal J, Manolaridis I, Jackson SM, Stahlberg H, Locher KP

EMDB-12952:
ABCG2 topotecan turnover-2 state
Method: single particle / : Yu Q, Ni D, Kowal J, Manolaridis I, Jackson SM, Stahlberg H, Locher KP

EMDB-12290:
Structure of tariquidar-bound ABCG2
Method: single particle / : Kowal J, Locher K

EMDB-12295:
Structure of topotecan-bound ABCG2
Method: single particle / : Kowal J, Locher K, Ni D, Stahlberg H

EMDB-12300:
Structure of mitoxantrone-bound ABCG2
Method: single particle / : Kowal J, Locher K, Ni D, Stahlberg H

EMDB-11667:
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and vincristine
Method: single particle / : Nosol K, Locher KP

EMDB-11666:
Nanodisc reconstituted, drug-free human ABCB1 in complex with MRK16 Fab
Method: single particle / : Nosol K, Locher KP

EMDB-11670:
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and elacridar
Method: single particle / : Nosol K, Locher KP

EMDB-11671:
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar
Method: single particle / : Nosol K, Locher KP

EMDB-11672:
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar
Method: single particle / : Nosol K, Locher KP

EMDB-10257:
Cryo-EM structure of yeast ALG6 in complex with 6AG9 Fab and Dol25-P-Glc
Method: single particle / : Bloch JS, Pesciullesi G, Boilevin J, Nosol K, Irobalieva RN, Darbre T, Aebi M, Kossiakoff AA, Reymond JL, Locher KP

EMDB-10258:
Cryo-EM structure of nanodisc reconstituted yeast ALG6 in complex with 6AG9 Fab
Method: single particle / : Bloch JS, Pesciullesi G, Boilevin J, Nosol K, Irobalieva RN, Darbre T, Aebi M, Kossiakoff AA, Reymond JL, Locher KP

EMDB-10111:
Nucleotide bound ABCB4
Method: single particle / : Olsen JA, Alam A, Kowal J, Stieger B, Locher KP

EMDB-10110:
Cryo-EM structure of human oligosaccharyltransferase complex OST-A
Method: single particle / : Ramirez AS, Kowal J, Locher KP

EMDB-10112:
Cryo-EM structure of human oligosaccharyltransferase complex OST-B
Method: single particle / : Ramirez AS, Kowal J, Locher KP

EMDB-4536:
Nanodisc reconstituted Human-mouse chimeric ABCB1 (ABCB1HM)-EQ mutant in complex with UIC2 Fab and Zosuquidar.
Method: single particle / : Alam A

EMDB-4539:
Nanodisc reconstituted human ABCB1 in complex with UIC2 fab and taxol
Method: single particle / : Alam A, Locher KP

EMDB-4540:
Structural insight into substrate and inhibitor discrimination by human P-glycoprotein
Method: single particle / : Alam A, Locher KP

EMDB-4541:
Nanodisc reconstituted human ABCB1 in complex with UIC2 fab and taxol
Method: single particle / : Alam A, Locher KP

EMDB-0190:
Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium
Method: single particle / : Manolaridis I, Jackson SM, Taylor NMI, Kowal J, Stahlberg H, Locher KP

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

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