Author results

1F03
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SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT (E44A, E48A, E56A, D60A) AND ITS INTERACTION WITH CYTOCHROME C
Descriptor:CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Wu, Y.B., Lu, J., Qian, C.M., Tang, W.X., Li, E.C., Wang, J.F., Wang, Y.H., Wang, W.H., Lu, J.X., Xie, Y., Huang, Z.X.
Deposit date:2000-05-14
Release date:2000-06-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of cytochrome b(5) mutant (E44/48/56A/D60A) and its interaction with cytochrome c.
Eur.J.Biochem., 268, 2001
1F04
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SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT (E44A, E48A, E56A, D60A) AND ITS INTERACTION WITH CYTOCHROME C
Descriptor:CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Wu, Y.B., Lu, J., Qian, C.M., Tang, W.X., Li, E.C., Wang, J.F., Wang, Y.H., Wang, W.H., Lu, J.X., Xie, Y., Huang, Z.X.
Deposit date:2000-05-14
Release date:2000-06-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of cytochrome b(5) mutant (E44/48/56A/D60A) and its interaction with cytochrome c.
Eur.J.Biochem., 268, 2001
1FI7
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SOLUTION STRUCTURE OF THE IMIDAZOLE COMPLEX OF CYTOCHROME C
Descriptor:CYTOCHROME C, IMIDAZOLE, HEME C
Authors:Banci, L., Bertini, I., Liu, G., Lu, J., Reddig, T., Tang, W., Wu, Y., Zhu, D.
Deposit date:2000-08-03
Release date:2000-08-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Effects of extrinsic imidazole ligation on the molecular and electronic structure of cytochrome c
J.Biol.Inorg.Chem., 6, 2001
1FI9
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SOLUTION STRUCTURE OF THE IMIDAZOLE COMPLEX OF CYTOCHROME C
Descriptor:CYTOCHROME C, IMIDAZOLE, HEME C
Authors:Banci, L., Bertini, I., Liu, G., Lu, J., Reddig, T., Tang, W., Wu, Y., Zhu, D.
Deposit date:2000-08-03
Release date:2000-08-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Effects of extrinsic imidazole ligation on the molecular and electronic structure of cytochrome c
J.Biol.Inorg.Chem., 6, 2001
1Z5M
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CRYSTAL STRUCTURE OF N1-[3-[[5-BROMO-2-[[3-[(1-PYRROLIDINYLCARBONYL)AMINO]PHENYL]AMINO]-4-PYRIMIDINYL]AMINO]PROPYL]-2,2-DIMETHYLPROPANEDIAMIDE COMPLEXED WITH HUMAN PDK1
Descriptor:3-phosphoinositide dependent protein kinase-1, SULFATE ION, CHLORIDE ION, ...
Authors:Whitlow, M., Adler, M.
Deposit date:2005-03-18
Release date:2005-04-19
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1.
J.Biol.Chem., 280, 2005
2PE0
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CRYSTAL STRUCTURE OF HUMAN PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 (PDK1) 5-HYDROXY-3-[1-(1H-PYRROL-2-YL)-ETH-(Z)-YLIDENE]-1,3-DIHYDRO-INDOL-2-ONE COMPLEX
Descriptor:3-phosphoinositide-dependent protein kinase 1, SULFATE ION, 5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE, ...
Authors:Whitlow, M., Adler, M.
Deposit date:2007-04-01
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: Design, synthesis and biological activity.
Bioorg.Med.Chem.Lett., 17, 2007
2PE1
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CRYSTAL STRUCTURE OF HUMAN PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 (PDK1) {2-OXO-3-[1-(1H-PYRROL-2-YL)-ETH-(Z)-YLIDENE]-2,3-DIHYDRO-1H-INDOL-5-YL}-UREA {BX-517} COMPLEX
Descriptor:3-phosphoinositide-dependent protein kinase 1, SULFATE ION, 1-{2-OXO-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-5-YL}UREA, ...
Authors:Whitlow, M., Adler, M.
Deposit date:2007-04-01
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: Design, synthesis and biological activity.
Bioorg.Med.Chem.Lett., 17, 2007
2PE2
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CRYSTAL STRUCTURE OF HUMAN PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 (PDK1) 3-{5-[2-OXO-5-UREIDO-1,2-DIHYDRO-INDOL-(3Z)-YLIDENEMETHYL]-1H-PYRROL-3-YL}-N-(2-PIPERIDIN-1-YL-ETHYL)-BENZAMIDE COMPLEX
Descriptor:3-phosphoinositide-dependent protein kinase 1, SULFATE ION, 3-[5-({5-[(AMINOCARBONYL)AMINO]-2-OXO-2H-INDOL-3-YL}METHYL)-1H-PYRROL-3-YL]-N-(2-PIPERIDIN-1-YLETHYL)BENZAMIDE, ...
Authors:Whitlow, M., Adler, M.
Deposit date:2007-04-01
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: Optimization of BX-517.
Bioorg.Med.Chem.Lett., 17, 2007
3A0C
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CRYSTAL STRUCTURE OF AN ANTI-HIV MANNOSE-BINDING LECTIN FROM POLYGONATUM CYRTONEMA HUA
Descriptor:Mannose/sialic acid-binding lectin
Authors:Ding, J., Wang, D.C.
Deposit date:2009-03-16
Release date:2010-03-16
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of a novel anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua with unique ligand-binding property and super-structure
J.Struct.Biol., 171, 2010
3A0D
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CRYSTAL STRUCTURE OF POLYGONATUM CYRTONEMA LECTIN (PCL) COMPLEXED WITH MONOMANNOSIDE
Descriptor:Mannose/sialic acid-binding lectin, O1-METHYL-MANNOSE, SULFATE ION
Authors:Ding, J., Wang, D.C.
Deposit date:2009-03-16
Release date:2010-03-16
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of a novel anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua with unique ligand-binding property and super-structure
J.Struct.Biol., 171, 2010
3A0E
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CRYSTAL STRUCTURE OF POLYGONATUM CYRTONEMA LECTIN (PCL) COMPLEXED WITH DIMANNOSIDE
Descriptor:Mannose/sialic acid-binding lectin, 3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose, SULFATE ION
Authors:Ding, J., Wang, D.C.
Deposit date:2009-03-16
Release date:2010-03-16
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of a novel anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua with unique ligand-binding property and super-structure
J.Struct.Biol., 171, 2010
3HHU
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HUMAN HEAT-SHOCK PROTEIN 90 (HSP90) IN COMPLEX WITH {4-[3-(2,4-DIHYDROXY-5-ISOPROPYL-PHENYL)-5-THIOXO- 1,5-DIHYDRO-[1,2,4]TRIAZOL-4-YL]-BENZYL}-CARBAMIC ACID ETHYL ESTER {ZK 2819}
Descriptor:Heat shock protein HSP 90-alpha, ethyl (4-{3-[2,4-dihydroxy-5-(1-methylethyl)phenyl]-5-sulfanyl-4H-1,2,4-triazol-4-yl}benzyl)carbamate
Authors:Adler, M., Whitlow, M.
Deposit date:2009-05-17
Release date:2009-07-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Potent triazolothione inhibitor of heat-shock protein-90.
Chem.Biol.Drug Des., 74, 2009
3K49
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PUF3 RNA BINDING DOMAIN BOUND TO COX17 RNA 3' UTR RECOGNITION SEQUENCE SITE B
Descriptor:mRNA-binding protein PUF3, RNA (5'-R(*CP*CP*UP*GP*UP*AP*AP*AP*UP*A)-3'), CITRIC ACID
Authors:Zhu, D., Stumpf, C.R., Krahn, J.M., Wickens, M., Hall, T.M.T.
Deposit date:2009-10-05
Release date:2009-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A 5' cytosine binding pocket in Puf3p specifies regulation of mitochondrial mRNAs.
Proc.Natl.Acad.Sci.USA, 106, 2009
3K4E
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PUF3 RNA BINDING DOMAIN BOUND TO COX17 RNA 3' UTR RECOGNITION SEQUENCE SITE A
Descriptor:mRNA-binding protein PUF3, RNA (5'-R(P*CP*UP*UP*GP*UP*AP*UP*AP*UP*A)-3')
Authors:Zhu, D., Stumpf, C.R., Krahn, J.M., Wickens, M., Hall, T.M.T.
Deposit date:2009-10-05
Release date:2009-10-27
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A 5' cytosine binding pocket in Puf3p specifies regulation of mitochondrial mRNAs.
Proc.Natl.Acad.Sci.USA, 106, 2009
3O72
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CRYSTAL STRUCTURE OF EFEB IN COMPLEX WITH HEME
Descriptor:Redox component of a tripartite ferrous iron transporter, PROTOPORPHYRIN IX CONTAINING FE, OXYGEN MOLECULE
Authors:Liu, X., Du, Q., Wang, Z., Zhu, D., Huang, Y., Li, N., Xu, S., Gu, L.
Deposit date:2010-07-30
Release date:2011-03-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure and biochemical features of EfeB/YcdB from Escherichia coli O157: ASP235 plays divergent roles in different enzyme-catalyzed processes
J.Biol.Chem., 286, 2011
3Q7J
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ENGINEERED THERMOPLASMA ACIDOPHILUM F3 FACTOR MIMICS HUMAN AMINOPEPTIDASE N (APN) AS A TARGET FOR ANTICANCER DRUG DEVELOPMENT
Descriptor:Tricorn protease-interacting factor F3, ZINC ION, L-phenylalanyl-N6-[(benzyloxy)carbonyl]-N1-hydroxy-L-lysinamide
Authors:Su, J., Wang, Q., Feng, J., Zhang, C., Zhu, D., We, T., Xu, W., Gu, L.
Deposit date:2011-01-05
Release date:2011-07-27
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Engineered Thermoplasma acidophilum factor F3 mimics human aminopeptidase N (APN) as a target for anticancer drug development
Bioorg.Med.Chem., 19, 2011
3SFV
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CRYSTAL STRUCTURE OF THE GDP-BOUND RAB1A S25N MUTANT IN COMPLEX WITH THE COILED-COIL DOMAIN OF LIDA FROM LEGIONELLA PNEUMOPHILA
Descriptor:Ras-related protein Rab-1A, LidA protein, substrate of the Dot/Icm system, ...
Authors:Yin, K., Lu, D., Zhu, D., Zhang, H., Li, B., Xu, S., Gu, L.
Deposit date:2011-06-14
Release date:2012-04-18
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State
Plos Pathog., 8, 2012
3SP4
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CRYSTAL STRUCTURE OF APRATAXIN ORTHOLOG HNT3 FROM SCHIZOSACCHAROMYCES POMBE
Descriptor:Aprataxin-like protein, ZINC ION, SULFATE ION
Authors:Gong, Y., Zhu, D., Ding, J., Dou, C., Ren, X., Jiang, T., Wang, D.
Deposit date:2011-07-01
Release date:2011-10-12
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
3SPD
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CRYSTAL STRUCTURE OF APRATAXIN ORTHOLOG HNT3 IN COMPLEX WITH DNA
Descriptor:Aprataxin-like protein, DNA (5'-D(*TP*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*GP*AP*G)-3'), ...
Authors:Gong, Y., Zhu, D., Ding, J., Dou, C., Ren, X., Jiang, T., Wang, D.
Deposit date:2011-07-01
Release date:2011-10-12
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (1.912 Å)
Cite:Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
3SPL
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CRYSTAL STRUCTURE OF APRATAXIN ORTHOLOG HNT3 IN COMPLEX WITH DNA AND AMP
Descriptor:Aprataxin-like protein, DNA (5'-D(*TP*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*GP*AP*G)-3'), ...
Authors:Gong, Y., Zhu, D., Ding, J., Dou, C., Ren, X., Jiang, T., Wang, D.
Deposit date:2011-07-02
Release date:2011-10-12
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
3TB4
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CRYSTAL STRUCTURE OF THE ISC DOMAIN OF VIBB
Descriptor:Vibriobactin-specific isochorismatase, B-OCTYLGLUCOSIDE, TRIETHYLENE GLYCOL, ...
Authors:Liu, S., Zhang, C., Niu, B., Li, N., Liu, M., Wei, T., Zhu, D., Xu, S., Gu, L.
Deposit date:2011-08-05
Release date:2012-08-29
Last modified:2014-01-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural insight into the ISC domain of VibB from Vibrio cholerae at atomic resolution: a snapshot just before the enzymatic reaction
Acta Crystallogr.,Sect.D, 68, 2012
3TEF
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CRYSTAL STRUCTURE OF THE PERIPLASMIC CATECHOLATE-SIDEROPHORE BINDING PROTEIN VCTP FROM VIBRIO CHOLERAE
Descriptor:Iron(III) ABC transporter, periplasmic iron-compound-binding protein
Authors:Liu, X., Wang, Z., Liu, S., Li, N., Chen, Y., Zhu, C., Zhu, D., Wei, T., Huang, Y., Xu, S., Gu, L.
Deposit date:2011-08-13
Release date:2012-08-15
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Crystal structure of periplasmic catecholate-siderophore binding protein VctP from Vibrio cholerae at 1.7 A resolution
Febs Lett., 586, 2012
3TG2
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CRYSTAL STRUCTURE OF THE ISC DOMAIN OF VIBB IN COMPLEX WITH ISOCHORISMATE
Descriptor:Vibriobactin-specific isochorismatase, (5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid, TRIETHYLENE GLYCOL
Authors:Liu, S., Zhang, C., Niu, B., Li, N., Liu, X., Liu, M., Wei, T., Zhu, D., Huang, Y., Xu, S., Gu, L.
Deposit date:2011-08-17
Release date:2012-08-29
Last modified:2014-01-01
Method:X-RAY DIFFRACTION (1.101 Å)
Cite:Structural insight into the ISC domain of VibB from Vibrio cholerae at atomic resolution: a snapshot just before the enzymatic reaction
Acta Crystallogr.,Sect.D, 68, 2012
3TGV
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CRYSTAL STRUCTURE OF HUTZ,THE HEME STORSGE PROTEIN FROM VIBRIO CHOLERAE
Descriptor:Heme-binding protein HutZ, BENZOIC ACID
Authors:Liu, X., Gong, J., Wang, Z., Du, Q., Wei, T., Zhu, D., Huang, Y., Xu, S., Gu, L.
Deposit date:2011-08-17
Release date:2012-08-22
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Crystal structure of HutZ,the heme storsge protein from Vibrio cholerae
To be Published
3TKL
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CRYSTAL STRUCTURE OF THE GTP-BOUND RAB1A IN COMPLEX WITH THE COILED-COIL DOMAIN OF LIDA FROM LEGIONELLA PNEUMOPHILA
Descriptor:Ras-related protein Rab-1A, LidA protein, substrate of the Dot/Icm system, ...
Authors:Cheng, W., Yin, K., Lu, D., Li, B., Zhu, D., Chen, Y., Zhang, H., Xu, S., Chai, J., Gu, L.
Deposit date:2011-08-27
Release date:2012-06-27
Method:X-RAY DIFFRACTION (2.183 Å)
Cite:Structural insights into a unique Legionella pneumophila effector LidA recognizing both GDP and GTP bound Rab1 in their active state
Plos Pathog., 8, 2012