3TKL

Crystal structure of the GTP-bound Rab1a in complex with the coiled-coil domain of LidA from Legionella pneumophila

Summary for 3TKL

• Entry DOI: 10.2210/pdb3tkl/pdb
• Related: 3sfv
• Descriptor: Ras-related protein Rab-1A, LidA protein, substrate of the Dot/Icm system, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: vesicle trafficking, protein transport-protein binding complex, protein transport/protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Golgi apparatus: P62820
• Total number of polymer chains: 2
• Total formula weight: 52948.76

Authors

Cheng, W.,Yin, K.,Lu, D.,Li, B.,Zhu, D.,Chen, Y.,Zhang, H.,Xu, S.,Chai, J.,Gu, L. (deposition date: 2011-08-27, release date: 2012-06-27, Last modification date: 2023-11-01)

• Primary citation: Cheng, W.,Yin, K.,Lu, D.,Li, B.,Zhu, D.,Chen, Y.,Zhang, H.,Xu, S.,Chai, J.,Gu, L.; Structural insights into a unique Legionella pneumophila effector LidA recognizing both GDP and GTP bound Rab1 in their active state; Plos Pathog., 8:e1002528-e1002528, 2012; PubMed: 22416225; DOI: 10.1371/journal.ppat.1002528

Experimental method

X-RAY DIFFRACTION (2.183 Å)