3TKL

Crystal structure of the GTP-bound Rab1a in complex with the coiled-coil domain of LidA from Legionella pneumophila

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Ras-related protein Rab-1A	polymer	196	21766.6	1	UniProt (P62820) Pfam (PF00071)	Homo sapiens (human)	YPT1-related protein
2	B (B)	LidA protein, substrate of the Dot/Icm system	polymer	267	30634.6	1	UniProt (A5IFX1)	Legionella pneumophila
3	C (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	D (A)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	1	Chemie (GTP)
5	E, F (A, B)	water	water		18.0	111	Chemie (HOH)

Sequence modifications

A: 1 - 191 (UniProt: P62820)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B: 187 - 449 (UniProt: A5IFX1)

PDB	External Database	Details
Gly 183	-	expression tag
Pro 184	-	expression tag
Leu 185	-	expression tag
Gly 186	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	52401.3
Non-Polymers*	Number of molecules	2
	Total formula weight	547.5
All*	Total formula weight	52948.8

*Water molecules are not included.