Author results

1WRS
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NMR STUDY OF HOLO TRP REPRESSOR
Descriptor:HOLO TRP REPRESSOR, TRYPTOPHAN
Authors:Zhao, D., Zheng, Z.
Deposit date:1995-05-12
Release date:1996-06-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Refined solution structures of the Escherichia coli trp holo- and aporepressor.
J.Mol.Biol., 229, 1993
1WRT
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NMR STUDY OF APO TRP REPRESSOR
Descriptor:APO TRP REPRESSOR
Authors:Zhao, D., Zheng, Z.
Deposit date:1995-05-12
Release date:1996-06-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Refined solution structures of the Escherichia coli trp holo- and aporepressor.
J.Mol.Biol., 229, 1993
1A3Z
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REDUCED RUSTICYANIN AT 1.9 ANGSTROMS
Descriptor:RUSTICYANIN, COPPER (I) ION
Authors:Zhao, D., Shoham, M.
Deposit date:1998-01-27
Release date:1998-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rusticyanin: Extremes in acid stability and redox potential explained by the crystal structure.
Biophys.J., 74, 1998
2MOX
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SOLUTION STRUCTURE OF TANDEM SH3 DOMAIN OF SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1
Descriptor:Sorbin and SH3 domain-containing protein 1
Authors:Zhao, D., Wang, C., Zhang, J., Wu, J., Shi, Y., Zhang, Z., Gong, Q.
Deposit date:2014-05-07
Release date:2014-05-28
Last modified:2014-12-10
Method:SOLUTION NMR
Cite:Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
4LN2
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THE SECOND SH3 DOMAIN FROM CAP/PONSIN IN COMPLEX WITH PROLINE RICH PEPTIDE FROM VINCULIN
Descriptor:Sorbin and SH3 domain-containing protein 1, proline rich peptide
Authors:Zhao, D., Li, F., Wu, J., Shi, Y., Zhang, Z., Gong, Q.
Deposit date:2013-07-11
Release date:2014-05-28
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
4LNP
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THE FIRST SH3 DOMAIN FROM CAP/PONSIN IN COMPLEX WITH PROLINE RICH PEPTIDE FROM VINCULIN
Descriptor:Sorbin and SH3 domain-containing protein 1, Vinculin
Authors:Zhao, D., Li, F., Wu, J., Shi, Y., Zhang, Z., Gong, Q.
Deposit date:2013-07-11
Release date:2014-05-28
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
5IQL
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CRYSTAL STRUCTURE OF YEATS2 YEATS BOUND TO H3K27CR PEPTIDE
Descriptor:YEATS domain-containing protein 2, Histone H3.1
Authors:Li, H., Zhao, D., Guan, H.
Deposit date:2016-03-11
Release date:2016-07-20
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:YEATS2 is a selective histone crotonylation reader.
Cell Res., 26, 2016
1RCS
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NMR STUDY OF TRP REPRESSOR-OPERATOR DNA COMPLEX
Descriptor:DNA (5'-D(*CP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*AP*CP*G)-3'), TRP REPRESSOR, TRYPTOPHAN
Authors:Zhao, D., Zheng, Z.
Deposit date:1995-05-12
Release date:1996-06-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structures of the trp repressor-operator DNA complex.
J.Mol.Biol., 238, 1994
4W5A
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COMPLEX STRUCTURE OF ATRX ADD BOUND TO H3K9ME3S10PH PEPTIDE
Descriptor:Transcriptional regulator ATRX, Peptide from Histone H3.3, ZINC ION
Authors:Zhao, D., Xiang, B., Li, H.
Deposit date:2014-08-17
Release date:2015-01-21
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons
Proc.Natl.Acad.Sci.USA, 112, 2015
5HJB
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AF9 YEATS IN COMPLEX WITH HISTONE H3 CROTONYLATION AT K9
Descriptor:Protein AF-9, peptide of Histone H3.1
Authors:Li, Y.Y., Zhao, D., Guan, H.P., Li, H.T.
Deposit date:2016-01-12
Release date:2016-04-20
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
5HJC
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BRD3 SECOND BROMODOMAIN IN COMPLEX WITH HISTONE H3 ACETYLATION AT K18
Descriptor:Bromodomain-containing protein 3, peptide of Histone H3.1, 1,2-ETHANEDIOL, ...
Authors:Li, Y.Y., Zhao, D., Guan, H.P., Li, H.T.
Deposit date:2016-01-13
Release date:2016-04-20
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
5HJD
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AF9 YEATS IN COMPLEX WITH HISTONE H3 CROTONYLATION AT K18
Descriptor:Protein AF-9, peptide of Histone H3.1, COPPER (II) ION, ...
Authors:Li, Y.Y., Zhao, D., Guan, H.P., Li, H.T.
Deposit date:2016-01-13
Release date:2016-04-20
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.806 Å)
Cite:Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain.
Mol.Cell, 62, 2016
5XTZ
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CRYSTAL STRUCTURE OF GAS41 YEATS BOUND TO H3K27AC PEPTIDE
Descriptor:YEATS domain-containing protein 4, THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, ACETATE ION
Authors:Li, H.T., Zhao, D.
Deposit date:2017-06-21
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity.
Cell Discov, 4, 2018
1JAK
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STREPTOMYCES PLICATUS BETA-N-ACETYLHEXOSAMINIDASE IN COMPLEX WITH (2R,3R,4S,5R)-2-ACETAMIDO-3,4-DIHYDROXY-5-HYDROXYMETHYL-PIPERIDINIUM CHLORIDE (IFG)
Descriptor:Beta-N-acetylhexosaminidase, SULFATE ION, CHLORIDE ION, ...
Authors:Mark, B.L., Vocadlo, D.J., Zhao, D., Knapp, S., Withers, S.G., James, M.N.
Deposit date:2001-05-30
Release date:2001-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Biochemical and structural assessment of the 1-N-azasugar GalNAc-isofagomine as a potent family 20 beta-N-acetylhexosaminidase inhibitor.
J.Biol.Chem., 276, 2001
1NOU
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NATIVE HUMAN LYSOSOMAL BETA-HEXOSAMINIDASE ISOFORM B
Descriptor:beta-hexosaminidase beta chain, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ...
Authors:Mark, B.L., Mahuran, D.J., Cherney, M.M., Zhao, D., Knapp, S., James, M.N.G.
Deposit date:2003-01-16
Release date:2003-04-08
Last modified:2012-11-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of Human beta-hexosaminidase B: Understanding the molecular basis of Sandhoff and Tay-Sachs disease
J.Mol.Biol., 327, 2003
1NOW
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HUMAN LYSOSOMAL BETA-HEXOSAMINIDASE ISOFORM B IN COMPLEX WITH (2R,3R,4S,5R)-2-ACETAMIDO-3,4-DIHYDROXY-5-HYDROXYMETHYL-PIPERIDINIUM CHLORIDE (GALNAC-ISOFAGOMINE)
Descriptor:beta-hexosaminidase beta chain, N-ACETYL-D-GLUCOSAMINE, (2R,3R,4S,5R)-2-ACETAMIDO-3,4-DIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE, ...
Authors:Mark, B.L., Mahuran, D.J., Cherney, M.M., Zhao, D., Knapp, S., James, M.N.G.
Deposit date:2003-01-16
Release date:2003-04-29
Last modified:2012-11-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Human beta-hexosaminidase B: Understanding the molecular basis of Sandhoff and Tay-Sachs disease
J.Mol.Biol., 327, 2003
1NP0
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HUMAN LYSOSOMAL BETA-HEXOSAMINIDASE ISOFORM B IN COMPLEX WITH INTERMEDIATE ANALOGUE NAG-THIAZOLINE
Descriptor:Beta-hexosaminidase subunit beta, Beta-hexosaminidase subunit beta chain B, Beta-hexosaminidase subunit beta chain A, ...
Authors:Mark, B.L., Mahuran, D.J., Cherney, M.M., Zhao, D., Knapp, S., James, M.N.G.
Deposit date:2003-01-16
Release date:2003-04-29
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Human beta-hexosaminidase B: Understanding the molecular basis of Sandhoff and Tay-Sachs disease
J.Mol.Biol., 327, 2003
3EIP
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CRYSTAL STRUCTURE OF COLICIN E3 IMMUNITY PROTEIN: AN INHIBITOR TO A RIBOSOME-INACTIVATING RNASE
Descriptor:PROTEIN (COLICIN E3 IMMUNITY PROTEIN), ZINC ION
Authors:Li, C., Zhao, D., Djebli, A., Shoham, M.
Deposit date:1999-03-29
Release date:1999-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of colicin E3 immunity protein: an inhibitor of a ribosome-inactivating RNase.
Structure Fold.Des., 7, 1999
5XNV
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CRYSTAL STRUCTURE OF YEATS2 YEATS BOUND TO H3K27AC PEPTIDE
Descriptor:YEATS domain-containing protein 2, ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, AMMONIUM ION, ...
Authors:Li, H.T., Guan, H.P., Zhao, D.
Deposit date:2017-05-24
Release date:2017-11-01
Method:X-RAY DIFFRACTION (2.696 Å)
Cite:YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.
Nat Commun, 8, 2017
5XVA
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CRYSTAL STRUCTURE OF PAK4 IN COMPLEX WITH INHIBITOR CZH216
Descriptor:Serine/threonine-protein kinase PAK 4, [6-chloranyl-4-[(5-methyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]-[(3R)-3-methylpiperazin-1-yl]methanone, ETHANOL
Authors:Zhao, F., Li, H.
Deposit date:2017-06-27
Release date:2018-02-07
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors.
J. Med. Chem., 61, 2018
5XVF
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CRYSTAL STRUCTURE OF PAK4 IN COMPLEX WITH INHIBITOR CZH062
Descriptor:Serine/threonine-protein kinase PAK 4, 2-(4-azanylpiperidin-1-yl)-6-chloranyl-N-(1-methylimidazol-4-yl)quinazolin-4-amine
Authors:Zhao, F., Li, H.
Deposit date:2017-06-27
Release date:2018-02-07
Method:X-RAY DIFFRACTION (2.655 Å)
Cite:Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors.
J. Med. Chem., 61, 2018
5XVG
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CRYSTAL STRUCTURE OF PAK4 IN COMPLEX WITH INHIBITOR CZH226
Descriptor:Serine/threonine-protein kinase PAK 4, [6-chloranyl-4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]-[(3R)-3-methylpiperazin-1-yl]methanone, ETHANOL, ...
Authors:Zhao, F., Li, H.
Deposit date:2017-06-27
Release date:2018-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors.
J. Med. Chem., 61, 2018
4RDN
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STRUCTURE OF YTH-YTHDF2 IN COMPLEX WITH M6A
Descriptor:YTH domain-containing family protein 2, N-methyladenosine, SULFATE ION
Authors:Li, F.D., Zhao, D.B., Wu, J.H., Shi, Y.Y.
Deposit date:2014-09-19
Release date:2014-12-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition.
Cell Res., 24, 2014
4RDO
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STRUCTURE OF YTH-YTHDF2 IN THE FREE STATE
Descriptor:YTH domain-containing family protein 2, SULFATE ION
Authors:Li, F.D., Zhao, D.B., Wu, J.H., Shi, Y.Y.
Deposit date:2014-09-19
Release date:2014-12-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition.
Cell Res., 24, 2014
6CO1
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STRUCTURE OF HUMAN TIRR IN COMPLEX WITH 53BP1 TUDOR DOMAINS
Descriptor:Tudor-interacting repair regulator protein, TP53-binding protein 1
Authors:Cui, G., Botuyan, M.V., Mer, G.
Deposit date:2018-03-10
Release date:2018-06-06
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.179 Å)
Cite:Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.
Nat. Struct. Mol. Biol., 25, 2018
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