Author results

1NVQ
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THE COMPLEX STRUCTURE OF CHECKPOINT KINASE CHK1/UCN-01
分子名称:Serine/threonine-protein kinase Chk1, Peptide ASVSA, SULFATE ION, ...
著者Zhao, B., Bower, M.J., McDevitt, P.J., Zhao, H., Davis, S.T., Johanson, K.O., Green, S.M., Concha, N.O., Zhou, B.B.
登録日2003-02-04
公開日2003-04-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Chk1 Inhibition by UCN-01
J.Biol.Chem., 277, 2002
1NVR
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THE COMPLEX STRUCTURE OF CHECKPOINT KINASE CHK1/STAUROSPORINE
分子名称:Serine/threonine-protein kinase Chk1, Peptide ASVSA, SULFATE ION, ...
著者Zhao, B., Bower, M.J., McDevitt, P.J., Zhao, H., Davis, S.T., Johanson, K.O., Green, S.M., Concha, N.O., Zhou, B.B.
登録日2003-02-04
公開日2003-04-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Chk1 Inhibition by UCN-01
J.Biol.Chem., 277, 2002
1NVS
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THE COMPLEX STRUCTURE OF CHECKPOINT KINASE CHK1/SB218078
分子名称:Serine/threonine-protein kinase Chk1, Peptide ASVSA, SULFATE ION, ...
著者Zhao, B., Bower, M.J., McDevitt, P.J., Zhao, H., Davis, S.T., Johanson, K.O., Green, S.M., Concha, N.O., Zhou, B.B.
登録日2003-02-04
公開日2003-04-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Chk1 Inhibition by UCN-01
J.Biol.Chem., 277, 2002
5UJB
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STRUCTURE OF A MCL-1 INHIBITOR BINDING TO SITE 3 OF HUMAN SERUM ALBUMIN
分子名称:Serum albumin, 4-{8-chloro-11-[3-(4-chloro-3,5-dimethylphenoxy)propyl]-1-oxo-7-(1,3,5-trimethyl-1H-pyrazol-4-yl)-4,5-dihydro-1H-[1,4]diazepino[1,2-a]indol-2(3H)-yl}-1-methyl-1H-indole-6-carboxylic acid, PHOSPHATE ION
著者Zhao, B.
登録日2017-01-17
公開日2017-05-03
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of a Myeloid cell leukemia-1 (Mcl-1) inhibitor bound to drug site 3 of Human Serum Albumin.
Bioorg. Med. Chem., 25, 2017
2D09
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A ROLE FOR ACTIVE SITE WATER MOLECULES AND HYDROXYL GROUPS OF SUBSTRATE FOR OXYGEN ACTIVATION IN CYTOCHROME P450 158A2
分子名称:putative cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, FLAVIOLIN, ...
著者Zhao, B., Waterman, M.R.
登録日2005-07-30
公開日2005-10-25
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of active site water molecules and substrate hydroxyl groups in oxygen activation by cytochrome P450 158A2: a new mechanism of proton transfer
J.Biol.Chem., 280, 2005
5JEK
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PHOSPHORYLATED MAVS IN COMPLEX WITH IRF-3
分子名称:Interferon regulatory factor 3, MAVS peptide
著者Zhao, B., Li, P.
登録日2016-04-18
公開日2016-06-15
最終更新日2016-06-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JEL
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PHOSPHORYLATED TRIF IN COMPLEX WITH IRF-3
分子名称:Interferon regulatory factor 3, Phosphorylated TRIF peptide
著者Zhao, B., Li, P.
登録日2016-04-18
公開日2016-06-15
最終更新日2016-06-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JEM
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COMPLEX OF IRF-3 WITH CBP
分子名称:Interferon regulatory factor 3, CREB-binding protein
著者Zhao, B., Li, P.
登録日2016-04-18
公開日2016-06-15
最終更新日2016-06-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JEO
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PHOSPHORYLATED ROTAVIRUS NSP1 IN COMPLEX WITH IRF-3
分子名称:Rotavirus NSP1 peptide, Interferon regulatory factor 3, PHOSPHATE ION
著者Zhao, B., Li, P.
登録日2016-04-18
公開日2016-06-15
最終更新日2016-06-29
実験手法X-RAY DIFFRACTION (1.719 Å)
主引用文献Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JER
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STRUCTURE OF ROTAVIRUS NSP1 BOUND TO IRF-3
分子名称:Rotavirus NSP1 peptide, Interferon regulatory factor 3
著者Zhao, B., Li, P.
登録日2016-04-18
公開日2016-06-15
最終更新日2016-06-29
実験手法X-RAY DIFFRACTION (2.913 Å)
主引用文献Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5U0B
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STRUCTURE OF FULL-LENGTH ZIKA VIRUS NS5
分子名称:Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ...
著者Zhao, B., Du, F.
登録日2016-11-23
公開日2017-03-29
最終更新日2017-04-12
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and function of the Zika virus full-length NS5 protein.
Nat Commun, 8, 2017
5U0C
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STRUCTURE OF ZIKA VIRUS NS5 RNA POLYMERASE DOMAIN
分子名称:NS5 RNA polymerase domain, ZINC ION
著者Zhao, B., Du, F.
登録日2016-11-23
公開日2017-03-29
最終更新日2017-04-12
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and function of the Zika virus full-length NS5 protein.
Nat Commun, 8, 2017
1ATK
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CRYSTAL STRUCTURE OF THE CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH THE COVALENT INHIBITOR E-64
分子名称:CATHEPSIN K, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE
著者Zhao, B., Smith, W.W., Janson, C.A., Abdel-Meguid, S.S.
登録日1996-12-19
公開日1998-02-04
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human osteoclast cathepsin K complex with E-64.
Nat.Struct.Biol., 4, 1997
1S1F
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CRYSTAL STRUCTURE OF STREPTOMYCES COELICOLOR A3(2) CYP158A2 FROM ANTIBIOTIC BIOSYNTHETIC PATHWAYS
分子名称:putative cytochrome P450, MERCURY (II) ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Zhao, B., Lamb, D.C., Lei, L., Sundaramoorthy, M., Podust, L.M., Waterman, M.R.
登録日2004-01-06
公開日2005-01-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2
J.Biol.Chem., 280, 2005
1SE6
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CRYSTAL STRUCTURE OF STREPTOMYCES COELICOLOR A3(2) CYP158A2 FROM ANTIBIOTIC BIOSYNTHETIC PATHWAYS
分子名称:putative cytochrome P450, SPERMINE (FULLY PROTONATED FORM), PROTOPORPHYRIN IX CONTAINING FE, ...
著者Zhao, B., Lamb, D.C., Lei, L., Sundaramoorthy, M., Podust, L.M., Waterman, M.R.
登録日2004-02-16
公開日2005-01-25
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2.
J.Biol.Chem., 280, 2005
1SIV
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THREE-DIMENSIONAL STRUCTURE OF A SIV PROTEASE(SLASH)INHIBITOR COMPLEX. IMPLICATIONS FOR THE DESIGN OF HIV-1 AND HIV-2 PROTEASE INHIBITORS
分子名称:SIV PROTEASE, methyl N-{(4S,5S)-5-[(L-alanyl-L-alanyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-valyl-L-valinate
著者Zhao, B., Abdel-Meguid, S.
登録日1993-08-24
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Three-dimensional structure of a simian immunodeficiency virus protease/inhibitor complex. Implications for the design of human immunodeficiency virus type 1 and 2 protease inhibitors.
Biochemistry, 32, 1993
1T93
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EVIDENCE FOR MULTIPLE SUBSTRATE RECOGNITION AND MOLECULAR MECHANISM OF C-C REACTION BY CYTOCHROME P450 CYP158A2 FROM STREPTOMYCES COELICOLOR A3(2)
分子名称:putative cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, FLAVIOLIN
著者Zhao, B., Sundaramoorthy, M., Waterman, M.R.
登録日2004-05-14
公開日2005-01-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2.
J.Biol.Chem., 280, 2005
2D0E
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SUBSTRATE ASSITED IN OXYGEN ACTIVATION IN CYTOCHROME P450 158A2
分子名称:putative cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, 2-HYDROXYNAPHTHOQUINONE
著者Zhao, B., Waterman, M.R.
登録日2005-08-02
公開日2005-10-25
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Role of active site water molecules and substrate hydroxyl groups in oxygen activation by cytochrome P450 158A2: a new mechanism of proton transfer
J.Biol.Chem., 280, 2005
2DKK
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STRUCTURE/FUNCTION STUDIES OF CYTOCHROME P450 158A1 FROM STREPTOMYCES COELICOLOR A3(2)
分子名称:cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, IMIDAZOLE
著者Zhao, B.
登録日2006-04-12
公開日2007-04-17
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2.
Biochemistry, 46, 2007
2MY5
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SOLUTION STRUCTURE OF KSTB-PCP IN KOSINOSTATIN BIOSYNTHESIS
分子名称:Peptidyl carrier protein, N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-(2-sulfanylethyl)-beta-alaninamide
著者Zhao, B., Lan, W., Wang, C., Tang, G., Cao, C.
登録日2015-01-20
公開日2016-01-20
実験手法SOLUTION NMR
主引用文献1H and 15N Assigned Chemical Shifts for KstB-PCP
To be Published
2MY6
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STRUCTURE OF KSTB-PCP(APO)
分子名称:Peptidyl carrier protein
著者Zhao, B., Lan, W., Wang, C., Tang, G., Cao, C.
登録日2015-01-20
公開日2016-01-20
実験手法SOLUTION NMR
主引用文献1H and 15N Assigned Chemical Shifts for KstB-PCP
To be Published
2NZ5
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STRUCTURE AND FUNCTION STUDIES OF CYTOCHROME P450 158A1 FROM STREPTOMYCES COELICOLOR A3(2)
分子名称:Cytochrome P450 CYP158A1, PROTOPORPHYRIN IX CONTAINING FE, naphthalene-1,2,4,5,7-pentol
著者Zhao, B., Lamb, D.C., Kelly, S.L., Waterman, M.R.
登録日2006-11-22
公開日2007-07-03
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2.
Biochemistry, 46, 2007
2NZA
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STRUCTURE AND FUNCTION STUDIES OF CYTOCHROME P450 158A1 FROM STREPTOMYCES COELICOLOR A3(2)
分子名称:Cytochrome P450 CYP158A1, PROTOPORPHYRIN IX CONTAINING FE
著者Zhao, B., Waterman, M.R.
登録日2006-11-22
公開日2007-07-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2.
Biochemistry, 46, 2007
2R5T
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CRYSTAL STRUCTURE OF INACTIVE SERUM AND GLUCOCORTICOID- REGULATED KINASE 1 IN COMPLEX WITH AMP-PNP
分子名称:Serine/threonine-protein kinase Sgk1, MAGNESIUM ION, SULFATE ION, ...
著者Zhao, B., Lehr, R., Smallwood, A.M., Ho, T.F., Maley, K., Randall, T., Head, M.S., Koretke, K.K., Schnackenberg, C.G.
登録日2007-09-04
公開日2008-09-09
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP PNP.
Protein Sci., 16, 2007
2SN3
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STRUCTURE OF SCORPION TOXIN VARIANT-3 AT 1.2 ANGSTROMS RESOLUTION
分子名称:SCORPION NEUROTOXIN (VARIANT 3), (4S)-2-METHYL-2,4-PENTANEDIOL
著者Zhao, B., Carson, M., Ealick, S.E., Bugg, C.E.
登録日1992-02-20
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of scorpion toxin variant-3 at 1.2 A resolution.
J.Mol.Biol., 227, 1992