5JEK

Phosphorylated MAVS in complex with IRF-3

Summary for 5JEK

• Entry DOI: 10.2210/pdb5jek/pdb
• Related: 5JEJ 5JEL 5JEM 5JEO 5JER
• Descriptor: Interferon regulatory factor 3, MAVS peptide (3 entities in total)
• Functional Keywords: innate immunity, signaling, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm : Q14653
• Total number of polymer chains: 4
• Total formula weight: 57564.68

Authors

Zhao, B.,Li, P. (deposition date: 2016-04-18, release date: 2016-06-15, Last modification date: 2016-06-29)

• Primary citation: Zhao, B.,Shu, C.,Gao, X.,Sankaran, B.,Du, F.,Shelton, C.L.,Herr, A.B.,Ji, J.Y.,Li, P.; Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.; Proc.Natl.Acad.Sci.USA, 113:E3403-E3412, 2016; PubMed: 27302953; DOI: 10.1073/pnas.1603269113

Experimental method

X-RAY DIFFRACTION (2.4 Å)