1NVR

The Complex Structure Of Checkpoint Kinase Chk1/Staurosporine

Summary for 1NVR

Related1nvq
DescriptorSerine/threonine-protein kinase Chk1, Peptide ASVSA, SULFATE ION, ... (5 entities in total)
Functional Keywordschk1-staurosporine complex, transferase
Biological sourceHomo sapiens (human)
Cellular locationNucleus O14757
Total number of polymer chains2
Total molecular weight34039.04
Authors
Zhao, B.,Bower, M.J.,McDevitt, P.J.,Zhao, H.,Davis, S.T.,Johanson, K.O.,Green, S.M.,Concha, N.O.,Zhou, B.B. (deposition date: 2003-02-04, release date: 2003-04-08, Last modification date: 2011-07-13)
Primary citation
Zhao, B.,Bower, M.J.,McDevitt, P.J.,Zhao, H.,Davis, S.T.,Johanson, K.O.,Green, S.M.,Concha, N.O.,Zhou, B.B.
Structural Basis for Chk1 Inhibition by UCN-01
J.Biol.Chem., 277:46609-46615, 2002
PubMed: 12244092 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M201233200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22280.8%3.0%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution