1NVQ

The Complex Structure Of Checkpoint Kinase Chk1/UCN-01

Summary for 1NVQ

DescriptorSerine/threonine-protein kinase Chk1, Peptide ASVSA, SULFATE ION, ... (5 entities in total)
Functional Keywordschk1-ucn-01 complex, transferase
Biological sourceHomo sapiens (human)
Cellular locationNucleus O14757
Total number of polymer chains2
Total molecular weight34055.04
Authors
Zhao, B.,Bower, M.J.,McDevitt, P.J.,Zhao, H.,Davis, S.T.,Johanson, K.O.,Green, S.M.,Concha, N.O.,Zhou, B.B. (deposition date: 2003-02-04, release date: 2003-04-08, Last modification date: 2011-07-13)
Primary citation
Zhao, B.,Bower, M.J.,McDevitt, P.J.,Zhao, H.,Davis, S.T.,Johanson, K.O.,Green, S.M.,Concha, N.O.,Zhou, B.B.
Structural Basis for Chk1 Inhibition by UCN-01
J.Biol.Chem., 277:46609-46615, 2002
PubMed: 12244092 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M201233200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23580.8%1.7%7.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution