2R5T

Crystal Structure of Inactive Serum and Glucocorticoid- Regulated Kinase 1 in Complex with AMP-PNP

Summary for 2R5T

• Entry DOI: 10.2210/pdb2r5t/pdb
• Descriptor: Serine/threonine-protein kinase Sgk1, MAGNESIUM ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: agc protein kinase, apoptosis, atp-binding, cytoplasm, endoplasmic reticulum, nucleotide-binding, nucleus, phosphorylation, serine/threonine-protein kinase, transferase, ubl conjugation
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 42929.88

Authors

Zhao, B.,Lehr, R.,Smallwood, A.M.,Ho, T.F.,Maley, K.,Randall, T.,Head, M.S.,Koretke, K.K.,Schnackenberg, C.G. (deposition date: 2007-09-04, release date: 2008-09-09, Last modification date: 2024-02-21)

• Primary citation: Zhao, B.,Lehr, R.,Smallwood, A.M.,Ho, T.F.,Maley, K.,Randall, T.,Head, M.S.,Koretke, K.K.,Schnackenberg, C.G.; Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP PNP.; Protein Sci., 16:2761-2769, 2007; PubMed: 17965184; DOI: 10.1110/ps.073161707

Experimental method

X-RAY DIFFRACTION (1.9 Å)