Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG A 600 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 700 |
| Chain | Residue |
| A | SER255 |
| A | THR256 |
| A | HOH737 |
| A | HOH778 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ANP A 500 |
| Chain | Residue |
| A | ALA125 |
| A | LYS127 |
| A | ASP177 |
| A | ILE179 |
| A | ARG190 |
| A | LYS224 |
| A | GLU226 |
| A | ASN227 |
| A | LEU229 |
| A | THR239 |
| A | HOH789 |
| A | HOH795 |
| A | HOH873 |
| A | HOH907 |
| A | ILE104 |
| A | GLY107 |
| A | SER108 |
| A | PHE109 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 33 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGKGSFGKVLlArhkaeevfyavkvlqkk.AILK |
| Chain | Residue | Details |
| A | ILE104-LYS136 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IvYrDLKpeNILL |
| Chain | Residue | Details |
| A | ILE218-LEU230 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine; by PDPK1","evidences":[{"source":"PubMed","id":"10191262","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine; by PKA","evidences":[{"source":"PubMed","id":"11096081","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | GLU226 | |
| A | ASP222 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | LYS224 | |
| A | ASP222 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | LYS224 | |
| A | ASP222 | |
| A | THR260 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | LYS224 | |
| A | ASP222 | |
| A | ASN227 | |
