2R5T
Crystal Structure of Inactive Serum and Glucocorticoid- Regulated Kinase 1 in Complex with AMP-PNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase Sgk1 | polymer | 373 | 42303.3 | 1 | UniProt (O00141) Pfam (PF00069) Pfam (PF00433) | Homo sapiens (Human) | Serum/glucocorticoid-regulated kinase 1 |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 5 | E (A) | water | water | 18.0 | 207 | Chemie (HOH) |
Sequence modifications
A: 60 - 431 (UniProt: O00141)
| PDB | External Database | Details |
|---|---|---|
| Gly 59 | - | expression tag |
| Ala 74 | Ser 74 | engineered mutation |
| Ala 78 | Ser 78 | engineered mutation |
| Ala 397 | Ser 397 | engineered mutation |
| Ala 401 | Ser 401 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42303.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 626.6 | |
| All* | Total formula weight | 42929.9 |
