Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4QF1
DownloadVisualize
BU of 4qf1 by Molmil
Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ...
Authors:Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F.
Deposit date:2014-05-19
Release date:2015-02-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved.
Immunity, 41, 2014
4RIS
DownloadVisualize
BU of 4ris by Molmil
Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk
Descriptor: CH58-UA Fab heavy chain, CH58-UA Fab light chain, Envelope glycoprotein
Authors:Nicely, N.I, Wiehe, K, Kepler, T.B, Jaeger, F.H, Dennison, S.M, Liao, H.-X, Alam, S.M, Hwang, K.-K, Bonsignori, M, Rerks-Ngarm, S, Nitayaphan, S, Pitisuttithum, P, Kaewkungwal, J, Robb, M.L, O'Connell, R.J, Michael, N.L, Kim, J.H, Haynes, B.F.
Deposit date:2014-10-07
Release date:2015-08-12
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee.
EBioMedicine, 2, 2015
4RIR
DownloadVisualize
BU of 4rir by Molmil
Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk
Descriptor: CH58-UA Fab heavy chain, CH58-UA Fab light chain
Authors:Nicely, N.I, Wiehe, K, Kepler, T.B, Jaeger, F.H, Dennison, S.M, Liao, H.-X, Alam, S.M, Hwang, K.-K, Bonsignori, M, Rerks-Ngarm, S, Nitayaphan, S, Pitisuttithum, P, Kaewkungwal, J, Robb, M.L, O'Connell, R.J, Michael, N.L, Kim, J.H, Haynes, B.F.
Deposit date:2014-10-07
Release date:2015-08-12
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee.
EBioMedicine, 2, 2015
5DD1
DownloadVisualize
BU of 5dd1 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
Descriptor: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN
Authors:Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F.
Deposit date:2015-08-24
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.597 Å)
Cite:Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
5DD0
DownloadVisualize
BU of 5dd0 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
Descriptor: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB HEAVY LIGHT, oligo peptide
Authors:Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F.
Deposit date:2015-08-24
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.488 Å)
Cite:Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
5KG9
DownloadVisualize
BU of 5kg9 by Molmil
Crystal structure of the gp120 v2 antibody RE505-22 Fab from IGH- and IGK-humanized mouse
Descriptor: Antibody RE505-22 Fab heavy chain, Antibody RE505-22 Fab light chain
Authors:Nicely, N.I.
Deposit date:2016-06-13
Release date:2017-01-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice.
J. Immunol., 198, 2017
8DTO
DownloadVisualize
BU of 8dto by Molmil
Vaccine elicited Antibody MU89 bound to CH848.D949.10.17_N133D_N138T.DS.SOSIP.664 HIV-1 Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Stalls, V, Acharya, P.
Deposit date:2022-07-26
Release date:2023-04-19
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction.
Cell Host Microbe, 32, 2024
8DY6
DownloadVisualize
BU of 8dy6 by Molmil
Vaccine elicited Antibody MU89+S27Y bound to CH848.D949.10.17_N133D_N138T.DS.SOSIP.664 HIV-1 Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Stalls, V, Acharya, P.
Deposit date:2022-08-03
Release date:2023-04-19
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.32 Å)
Cite:Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction.
Cell Host Microbe, 32, 2024
6VTU
DownloadVisualize
BU of 6vtu by Molmil
DH717.1 Fab monomer in complex with man9 glycan
Descriptor: DH717.1 heavy chain, DH717.1 light chain, GLYCEROL, ...
Authors:Fera, D, Bronkema, N.
Deposit date:2020-02-13
Release date:2020-12-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
7SG4
DownloadVisualize
BU of 7sg4 by Molmil
Structure of SARS-CoV S protein in complex with Receptor Binding Domain antibody DH1047
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Heavy chain, DH1047 light chain, ...
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-10-04
Release date:2021-11-10
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.
Sci Transl Med, 14, 2022
8CSA
DownloadVisualize
BU of 8csa by Molmil
Triple mutant (K417N-E484K-N501Y) SARS-CoV-2 spike protein in the 3-RBD-Down conformation (S-GSAS-D614G-K417N-E484K-N501Y)
Descriptor: Spike glycoprotein
Authors:Gobeil, S, Acharya, P.
Deposit date:2022-05-12
Release date:2022-07-20
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity
Science, 2021
5F9W
DownloadVisualize
BU of 5f9w by Molmil
Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235 in complex with HIV-1 clade A/E 93TH057 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of CH235-lineage antibody CH235, Light chain of CH235-lineage antibody CH235, ...
Authors:Chen, L, Zhou, T, Kwong, P.D.
Deposit date:2015-12-10
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8911 Å)
Cite:Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Cell, 165, 2016
5F96
DownloadVisualize
BU of 5f96 by Molmil
Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235.12 in complex with HIV-1 clade A/E 93TH057 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY CH235.12, ...
Authors:Zhou, T, Kwong, P.D.
Deposit date:2015-12-09
Release date:2016-03-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2407 Å)
Cite:Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Cell, 165, 2016
8G8C
DownloadVisualize
BU of 8g8c by Molmil
Crystal structure of DH1322.1 Fab in complex with HIV proximal MPER peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1322.1 heavy chain, DH1322.1 light chain, ...
Authors:Niyongabo, A, Janus, B.M, Ofek, G.
Deposit date:2023-02-17
Release date:2024-05-22
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 187, 2024
6XRJ
DownloadVisualize
BU of 6xrj by Molmil
Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage
Descriptor: DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment
Authors:Manne, K, Nicely, N.I, Acharya, P.
Deposit date:2020-07-13
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
5IIE
DownloadVisualize
BU of 5iie by Molmil
STRUCTURE OF THE UNLIGANDED ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3
Descriptor: antibody DH501 FabH chain, antibody DH501 light chain
Authors:Nicely, N.I, Haynes, B.F.
Deposit date:2016-03-01
Release date:2017-03-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.
Cell Rep, 18, 2017
5T4Z
DownloadVisualize
BU of 5t4z by Molmil
STRUCTURE OF THE ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3 WITH FREE MAN9 GLYCAN
Descriptor: CALCIUM ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, antibody DH501 Fab heavy chain, ...
Authors:Nicely, N.I, Haynes, B.F.
Deposit date:2016-08-30
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.991 Å)
Cite:Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.
Cell Rep, 18, 2017
7BH8
DownloadVisualize
BU of 7bh8 by Molmil
3H4-Fab HLA-E-VL9 co-complex
Descriptor: 3H4 Fab heavy chain, 3H4 Fab light chain, Beta-2-microglobulin, ...
Authors:Walters, L.C, Rozbesky, D.
Deposit date:2021-01-10
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.
Commun Biol, 5, 2022
6FY0
DownloadVisualize
BU of 6fy0 by Molmil
Crystal structure of a V2-directed, RV144 vaccine-like antibody from HIV-1 infection, CAP228-16H, bound to a heterologous V2 peptide
Descriptor: CAP228-16H Heavy Chain, CAP228-16H Light Chain, CAP45 V2 peptide, ...
Authors:Wibmer, C.K, Fernandes, M, Vijayakumar, B, Dirr, H.W, Sayed, Y, Moore, P.L, Morris, L.
Deposit date:2018-03-10
Release date:2018-11-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity.
Cell Rep, 25, 2018
6XRT
DownloadVisualize
BU of 6xrt by Molmil
Cryo-EM structure of SHIV-elicited RHA1.V2.01 in complex with HIV-1 Env BG505 DS-SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-07-13
Release date:2020-10-07
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth.
Science, 371, 2021
6XCJ
DownloadVisualize
BU of 6xcj by Molmil
Crystal Structure of DH650 Fab from a Rhesus Macaque in Complex with HIV-1 gp120 Core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH650 Fab Heavy Chain, DH650 Fab Light Chain, ...
Authors:Raymond, D.D, Chug, H, Harrison, S.C.
Deposit date:2020-06-08
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth.
Science, 371, 2021
8SAW
DownloadVisualize
BU of 8saw by Molmil
CryoEM structure of DH270.UCA.G57R-CH848.10.17DT
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.3.D0949.10.17chim.6R.SOSIP.664 gp120A, CH848.3.D0949.10.17chim.6R.SOSIP.664 gp41, ...
Authors:Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:2023-04-02
Release date:2023-04-19
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SAU
DownloadVisualize
BU of 8sau by Molmil
CryoEM structure of DH270.4-CH848.10.17
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ...
Authors:Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:2023-04-02
Release date:2023-04-19
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SAN
DownloadVisualize
BU of 8san by Molmil
CryoEM structure of VRC01-CH848.0836.10
Descriptor: CH848.0836.10 gp120, CH848.0836.10 gp41, VCR01 variable heavy chain, ...
Authors:Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:2023-04-01
Release date:2023-04-19
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SAR
DownloadVisualize
BU of 8sar by Molmil
CryoEM structure of DH270.6-CH848.10.17
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, ...
Authors:Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:2023-04-01
Release date:2023-04-19
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.82 Å)
Cite:Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon