4RIS
Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk
Summary for 4RIS
Entry DOI | 10.2210/pdb4ris/pdb |
Related | 4RIR |
Descriptor | Envelope glycoprotein, CH58-UA Fab heavy chain, CH58-UA Fab light chain, ... (4 entities in total) |
Functional Keywords | antibody, igg fold, immune system, hiv-1 gp120 v2 region |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 50256.80 |
Authors | Nicely, N.I.,Wiehe, K.,Kepler, T.B.,Jaeger, F.H.,Dennison, S.M.,Liao, H.-X.,Alam, S.M.,Hwang, K.-K.,Bonsignori, M.,Rerks-Ngarm, S.,Nitayaphan, S.,Pitisuttithum, P.,Kaewkungwal, J.,Robb, M.L.,O'Connell, R.J.,Michael, N.L.,Kim, J.H.,Haynes, B.F. (deposition date: 2014-10-07, release date: 2015-08-12, Last modification date: 2015-09-02) |
Primary citation | Nicely, N.I.,Wiehe, K.,Kepler, T.B.,Jaeger, F.H.,Dennison, S.M.,Rerks-Ngarm, S.,Nitayaphan, S.,Pitisuttithum, P.,Kaewkungwal, J.,Robb, M.L.,O'Connell, R.J.,Michael, N.L.,Kim, J.H.,Liao, H.X.,Munir Alam, S.,Hwang, K.K.,Bonsignori, M.,Haynes, B.F. Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee. EBioMedicine, 2:713-722, 2015 Cited by PubMed: 26288844DOI: 10.1016/j.ebiom.2015.06.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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