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4RIS

Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk

Summary for 4RIS
Entry DOI10.2210/pdb4ris/pdb
Related4RIR
DescriptorEnvelope glycoprotein, CH58-UA Fab heavy chain, CH58-UA Fab light chain, ... (4 entities in total)
Functional Keywordsantibody, igg fold, immune system, hiv-1 gp120 v2 region
Biological sourceHomo sapiens
More
Total number of polymer chains3
Total formula weight50256.80
Authors
Primary citationNicely, N.I.,Wiehe, K.,Kepler, T.B.,Jaeger, F.H.,Dennison, S.M.,Rerks-Ngarm, S.,Nitayaphan, S.,Pitisuttithum, P.,Kaewkungwal, J.,Robb, M.L.,O'Connell, R.J.,Michael, N.L.,Kim, J.H.,Liao, H.X.,Munir Alam, S.,Hwang, K.K.,Bonsignori, M.,Haynes, B.F.
Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee.
EBioMedicine, 2:713-722, 2015
Cited by
PubMed: 26288844
DOI: 10.1016/j.ebiom.2015.06.016
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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