4RIS
Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (P) | Envelope glycoprotein | polymer | 18 | 2136.5 | 1 | UniProt (K7Z4Z0) UniProt (by SIFTS) (Q70966) | Human immunodeficiency virus 1 | |
| 2 | B (H) | CH58-UA Fab heavy chain | polymer | 231 | 24949.9 | 1 | Homo sapiens | ||
| 3 | C (L) | CH58-UA Fab light chain | polymer | 216 | 23170.4 | 1 | Homo sapiens | ||
| 4 | D, E, F (P, H, L) | water | water | 18.0 | 233 | Chemie (HOH) |
Sequence modifications
P: 165 - 182 (UniProt: K7Z4Z0)
| PDB | External Database | Details |
|---|---|---|
| Ala 179 | Leu 174 | SEE REMARK 999 |
| Ala 181 | Val 176 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50256.8 | |
| All* | Total formula weight | 50256.8 |
