5A1Z
| Cryo-EM structure of Dengue virus serotype 2 strain PVP94-07 complexed with human antibody 2D22 Fab at 37 degrees C | Descriptor: | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - LIGHT CHAIN, ENVELOPE PROTEIN, ... | Authors: | Fibriansah, G, Ibarra, K.D, Ng, T.S, Smith, S.A, Tan, J.L, Lim, X.N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe Jr, J.E, Lok, S.M. | Deposit date: | 2015-05-06 | Release date: | 2015-07-15 | Last modified: | 2018-02-07 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349, 2015
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4UIF
| Cryo-EM structure of Dengue virus serotype 2 in complex with antigen-binding fragments of human antibody 2D22 | Descriptor: | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN PVP94 07 - ENVELOPE PROTEIN, ... | Authors: | Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.-N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe Junior, J.E, Lok, S.-M. | Deposit date: | 2015-03-30 | Release date: | 2015-07-15 | Last modified: | 2018-02-07 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349, 2015
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4UIH
| Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to the virus before 37 degree C incubation. | Descriptor: | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN NEW GUINEA-C E PROTEIN ECTODOMAIN | Authors: | Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe, J.E, Lok, S.-M. | Deposit date: | 2015-03-30 | Release date: | 2015-07-15 | Last modified: | 2018-02-07 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349, 2015
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4CCT
| Dengue 1 cryo-EM reconstruction | Descriptor: | DENGUE VIRUS 1 E PROTEIN, DENGUE VIRUS 1 M PROTEIN | Authors: | Kostyuchenko, V.A, Zhang, Q, Tan, J.L, Ng, T.S, Lok, S.M. | Deposit date: | 2013-10-28 | Release date: | 2013-11-06 | Last modified: | 2017-08-30 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Immature and Mature Dengue Serotype 1 Virus Structures Provide Insight Into the Maturation Process. J.Virol., 87, 2013
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4C2I
| Cryo-EM structure of Dengue virus serotype 1 complexed with Fab fragments of human antibody 1F4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Fibriansah, G, Tan, J.L, de Alwis, R, Smith, S.A, Ng, T.-S, Kostyuchenko, V.A, Ibarra, K.D, Harris, E, de Silva, A, Crowe Junior, J.E, Lok, S.-M. | Deposit date: | 2013-08-18 | Release date: | 2014-01-29 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | A Potent Anti-Dengue Human Antibody Preferentially Recognizes the Conformation of E Protein Monomers Assembled on the Virus Surface. Embo Mol.Med., 6, 2014
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3J6T
| Cryo-EM structure of Dengue virus serotype 3 at 37 degrees C | Descriptor: | envelope protein, membrane protein | Authors: | Fibriansah, G, Tan, J.L, Smith, S.A, de Alwis, R, Ng, T.-S, Kostyuchenko, V.A, Kukkaro, P, de Silva, A.M, Crowe Jr, J.E, Lok, S.-M. | Deposit date: | 2014-03-25 | Release date: | 2015-03-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins. Nat Commun, 6, 2015
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3J6S
| Cryo-EM structure of Dengue virus serotype 3 at 28 degrees C | Descriptor: | envelope protein, membrane protein | Authors: | Fibriansah, G, Tan, J.L, Smith, S.A, de Alwis, R, Ng, T.-S, Kostyuchenko, V.A, Kukkaro, P, de Silva, A.M, Crowe Jr, J.E, Lok, S.-M. | Deposit date: | 2014-03-24 | Release date: | 2015-03-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins. Nat Commun, 6, 2015
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3J6U
| Cryo-EM structure of Dengue virus serotype 3 in complex with human antibody 5J7 Fab | Descriptor: | Fab 5J7 heavy chain, Fab 5J7 light chain, envelope protein, ... | Authors: | Fibriansah, G, Tan, J.L, Smith, S.A, de Alwis, R, Ng, T.-S, Kostyuchenko, V.A, Kukkaro, P, de Silva, A.M, Crowe Jr, J.E, Lok, S.-M. | Deposit date: | 2014-03-26 | Release date: | 2015-03-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins. Nat Commun, 6, 2015
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4B03
| 6A Electron cryomicroscopy structure of immature Dengue virus serotype 1 | Descriptor: | DENGUE VIRUS 1 E PROTEIN, DENGUE VIRUS 1 PRM PROTEIN | Authors: | Kostyuchenko, V.A, Zhang, Q, Tan, L.C, Ng, T.S, Lok, S.M. | Deposit date: | 2012-06-28 | Release date: | 2013-06-05 | Last modified: | 2017-08-30 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Immature and Mature Dengue Serotype 1 Virus Structures Provide Insight Into the Maturation Process. J.Virol., 87, 2013
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7C2S
| Helical reconstruction of Dengue virus serotype 3 complexed with Fab C10 | Descriptor: | Heavy chain of Fab C10, envelope protein, light chain of Fab C10 | Authors: | Morrone, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Zhang, S, Lok, S.M. | Deposit date: | 2020-05-09 | Release date: | 2020-07-08 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (10.4 Å) | Cite: | High flavivirus structural plasticity demonstrated by a non-spherical morphological variant. Nat Commun, 11, 2020
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7C2T
| Helical reconstruction of Zika virus complexed with Fab C10 | Descriptor: | Heavy chain from Fab C10, Light chain from Fab C10, M protein, ... | Authors: | Morrone, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Zhang, S, Lok, S.M. | Deposit date: | 2020-05-09 | Release date: | 2020-07-08 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | High flavivirus structural plasticity demonstrated by a non-spherical morphological variant. Nat Commun, 11, 2020
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7DWT
| Cryo-EM structure of Dengue virus serotype 1 strain WestPac 74 in complex with human antibody 1C19 Fab at 37 deg C (Class 1 particle) | Descriptor: | Anti-dengue virus human monoclonal antibody 1C19 Fab heavy chain, Anti-dengue virus human monoclonal antibody 1C19 Fab light chain, envelope protein | Authors: | Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Shi, J, Lok, S.M. | Deposit date: | 2021-01-18 | Release date: | 2021-02-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (19 Å) | Cite: | Antibody affinity versus dengue morphology influences neutralization. Plos Pathog., 17, 2021
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7DWU
| Cryo-EM structure of Dengue virus serotype 1 strain WestPac 74 in complex with human antibody 1C19 Fab at 37 deg C (Class 2 particle) | Descriptor: | Anti-dengue virus human monoclonal antibody 1C19 Fab heavy chain, Anti-dengue virus human monoclonal antibody 1C19 Fab light chain, envelope protein | Authors: | Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Shi, J, Lok, S.M. | Deposit date: | 2021-01-18 | Release date: | 2021-02-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (19 Å) | Cite: | Antibody affinity versus dengue morphology influences neutralization. Plos Pathog., 17, 2021
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4M1L
| Complex of IQCG and Ca2+-bound CaM | Descriptor: | CALCIUM ION, Calmodulin, IQ domain-containing protein G, ... | Authors: | Liang, W.X, Chen, L.T, Chen, Z, Chen, S.J, Chen, S. | Deposit date: | 2013-08-03 | Release date: | 2014-05-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish Nat Commun, 5, 2014
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4LZX
| Complex of IQCG and Ca2+-free CaM | Descriptor: | Calmodulin, IQ domain-containing protein G, SULFATE ION | Authors: | Liang, W.X, Chen, L.T, Chen, Z, Chen, S.J, Chen, S. | Deposit date: | 2013-08-01 | Release date: | 2014-05-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish Nat Commun, 5, 2014
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