5A1Z
Cryo-EM structure of Dengue virus serotype 2 strain PVP94-07 complexed with human antibody 2D22 Fab at 37 degrees C
Summary for 5A1Z
Entry DOI | 10.2210/pdb5a1z/pdb |
EMDB information | 2996 |
Descriptor | ENVELOPE PROTEIN, MEMBRANE GLYCOPROTEIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - HEAVY CHAIN, ... (4 entities in total) |
Functional Keywords | virus, dengue virus, human antibody, cryo-em, neutralization |
Biological source | DENGUE VIRUS 2 More |
Cellular location | Host endoplasmic reticulum membrane ; Multi-pass membrane protein : G9FRP5 |
Total number of polymer chains | 12 |
Total formula weight | 264791.42 |
Authors | Fibriansah, G.,Ibarra, K.D.,Ng, T.S.,Smith, S.A.,Tan, J.L.,Lim, X.N.,Ooi, J.S.G.,Kostyuchenko, V.A.,Wang, J.,de Silva, A.M.,Harris, E.,Crowe Jr, J.E.,Lok, S.M. (deposition date: 2015-05-06, release date: 2015-07-15, Last modification date: 2024-05-08) |
Primary citation | Fibriansah, G.,Ibarra, K.D.,Ng, T.S.,Smith, S.A.,Tan, J.L.,Lim, X.N.,Ooi, J.S.,Kostyuchenko, V.A.,Wang, J.,de Silva, A.M.,Harris, E.,Crowe, J.E.,Lok, S.M. Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349:88-91, 2015 Cited by PubMed: 26138979DOI: 10.1126/science.aaa8651 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (6.9 Å) |
Structure validation
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