5A1Z
Cryo-EM structure of Dengue virus serotype 2 strain PVP94-07 complexed with human antibody 2D22 Fab at 37 degrees C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | ENVELOPE PROTEIN | polymer | 495 | 54258.6 | 3 | UniProt (G9FRP5) Pfam (PF00869) Pfam (PF02832) Pfam (PF21659) UniProt (by SIFTS) (E0WXJ2) | DENGUE VIRUS 2 | E PROTEIN |
| 2 | B, D, F (B, D, F) | MEMBRANE GLYCOPROTEIN | polymer | 72 | 8109.5 | 3 | UniProt (V5TI05) Pfam (PF01004) UniProt (by SIFTS) (E0WXJ2) | DENGUE VIRUS 2 | M PROTEIN |
| 3 | G, I, K (G, I, K) | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - HEAVY CHAIN | polymer | 128 | 13805.5 | 3 | HOMO SAPIENS (HUMAN) | ||
| 4 | H, J, L (H, J, L) | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - LIGHT CHAIN | polymer | 115 | 12090.3 | 3 | HOMO SAPIENS (HUMAN) |
Sequence modifications
B, D, F: 1 - 72 (UniProt: V5TI05)
| PDB | External Database | Details |
|---|---|---|
| Thr 71 | Ala 162 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 264791.4 | |
| All* | Total formula weight | 264791.4 |
