Author results

5UVI
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SERIAL MILLISECOND CRYSTALLOGRAPHY OF MEMBRANE AND SOLUBLE PROTEIN MICRO-CRYSTALS USING SYNCHROTRON RADIATION
Descriptor:Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, CHOLESTEROL, ...
Authors:Martin-Garcia, J.M., Conrad, C.E., Nelson, G., Stander, N., Zatsepin, N.A., Zook, J., Zhu, L., Geiger, J., Chun, E., Kissick, D., Hilgart, M.C., Ogata, C., Ishchenko, A., Nagaratnam, N., Roy-Chowdhury, S., Coe, J., Subramanian, G., Schaffer, A., James, D., Ketawala, G., Venugopalan, N., Xu, S., Corcoran, S., Ferguson, D., Weierstall, U., Spence, J.C.H., Cherezov, V., Fromme, P., Fischetti, R.F., Liu, W.
Deposit date:2017-02-20
Release date:2017-05-24
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation.
IUCrJ, 4, 2017
5UVJ
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SERIAL MILLISECOND CRYSTALLOGRAPHY OF MEMBRANE AND SOLUBLE PROTEIN MICRO-CRYSTALS USING SYNCHROTRON RADIATION
Descriptor:Lysozyme C, CHLORIDE ION, SODIUM ION
Authors:Martin-Garcia, J.M., Conrad, C.E., Nelson, G., Stander, N., Zatsepin, N.A., Zook, J., Zhu, L., Geiger, J., Chun, E., Kissick, D., Hilgart, M.C., Ogata, C., Ishchenko, A., Nagaratnam, N., Roy-Chowdhury, S., Coe, J., Subramanian, G., Schaffer, A., James, D., Ketawala, G., Venugopalan, N., Xu, S., Corcoran, S., Ferguson, D., Weierstall, U., Spence, J.C.H., Cherezov, V., Fromme, P., Fischetti, R.F., Liu, W.
Deposit date:2017-02-20
Release date:2017-05-24
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation.
IUCrJ, 4, 2017
5UVK
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SERIAL MILLISECOND CRYSTALLOGRAPHY OF MEMBRANE AND SOLUBLE PROTEIN MICRO-CRYSTALS USING SYNCHROTRON RADIATION
Descriptor:C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN
Authors:Martin-Garcia, J.M., Conrad, C.E., Nelson, G., Stander, N., Zatsepin, N.A., Zook, J., Zhu, L., Geiger, J., Chun, E., Kissick, D., Hilgart, M.C., Ogata, C., Ishchenko, A., Nagaratnam, N., Roy-Chowdhury, S., Coe, J., Subramanian, G., Schaffer, A., James, D., Ketawala, G., Venugopalan, N., Xu, S., Corcoran, S., Ferguson, D., Weierstall, U., Spence, J.C.H., Cherezov, V., Fromme, P., Fischetti, R.F., Liu, W.
Deposit date:2017-02-20
Release date:2017-05-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Serial Millisecond Crystallography of Membrane and Soluble Protein Micro-crystals using Synchrotron Radiation
Iucrj, 4, 2017
5UVL
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SERIAL MILLISECOND CRYSTALLOGRAPHY OF MEMBRANE AND SOLUBLE PROTEIN MICRO-CRYSTALS USING SYNCHROTRON RADIATION
Descriptor:Proteinase K, NITRATE ION, CALCIUM ION
Authors:Martin-Garcia, J.M., Conrad, C.E., Nelson, G., Stander, N., Zatsepin, N.A., Zook, J., Zhu, L., Geiger, J., Chun, E., Kissick, D., Hilgart, M.C., Ogata, C., Ishchenko, A., Nagaratnam, N., Roy-Chowdhury, S., Coe, J., Subramanian, G., Schaffer, A., James, D., Ketawala, G., Venugopalan, N., Xu, S., Corcoran, S., Ferguson, D., Weierstall, U., Spence, J.C.H., Cherezov, V., Fromme, P., Fischetti, R.F., Liu, W.
Deposit date:2017-02-20
Release date:2017-05-24
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation.
IUCrJ, 4, 2017
4YAB
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH 1-METHYL-5-(2-METHYL-1 3-THIAZOL-4-YL)-2 3-DIHYDRO-1H-INDOL-2-ONE (1)
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, 1-methyl-5-(2-methyl-1,3-thiazol-4-yl)-1,3-dihydro-2H-indol-2-one, ...
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-17
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
4YAD
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH 2,4-DIMETHOXY-N-(1-METHYL-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-6-YL)BENZENE-1-SULFONAMIDE (3B)
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, 2,4-dimethoxy-N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)benzenesulfonamide, ...
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-17
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
4YAT
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH N-(1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL)-4-METHOXYBENZENE-1-SULFONAMIDE (5B)
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, N-(1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-4-methoxybenzenesulfonamide
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-17
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
4YAX
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH N-[6-(4-METHOXYPHENOXY)-1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL]BENZENESULFONAMIDE (5G)
Descriptor:Transcription intermediary factor 1-alpha, N-[6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl]benzenesulfonamide, ZINC ION, ...
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-18
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
4YBM
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH N-{6-[3-(BENZYLOXY)PHENOXY]-1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL}-3,4-DIMETHOXYBENZENE-1-SULFONAMIDE (7B)
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, GLYCEROL, ...
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-18
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
4YBS
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH N-{1,3-DIMETHYL-6-[3-(2-METHYLPROPOXY)PHENOXY]-2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL}-1,2-DIMETHYL-1H-IMIDAZOLE-4-SULFONAMIDE (7G)
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, N-{1,3-dimethyl-6-[3-(2-methylpropoxy)phenoxy]-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl}-1,2-dimethyl-1H-imidazole-4-sulfonamide, ...
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-19
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
4YBT
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH N-{1,3-DIMETHYL-2-OXO-6-[3-(OXOLAN-3-YLMETHOXY)PHENOXY]-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL}-1-METHYL-1H-IMIDAZOLE-4-SULFONAMIDE (7L)
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, DIMETHYL SULFOXIDE, ...
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-19
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
4YC9
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CRYSTAL STRUCTURE OF TRIM24 PHD-BROMODOMAIN COMPLEXED WITH N-(6-{3-[4-(DIMETHYLAMINO)BUTOXY]-5-PROPOXYPHENOXY}-1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL)-3,4-DIMETHOXYBENZENE-1-SULFONAMIDE (8I)
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, GLYCEROL, ...
Authors:Poncet-Montange, G., Palmer, W., Jones, P.
Deposit date:2015-02-19
Release date:2015-06-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
5HD3
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FEMTOSECOND STRUCTURAL DYNAMICS DRIVES THE TRANS/CIS ISOMERIZATION IN PHOTOACTIVE YELLOW PROTEIN: DARK STRUCTURE OF PHOTOACTIVE YELLOW PROTEIN
Descriptor:Photoactive yellow protein
Authors:Pande, K., Tenboer, J., Schmidt, M.
Deposit date:2016-01-04
Release date:2016-05-18
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein.
Science, 352, 2016
5HD5
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FEMTOSECOND STRUCTURAL DYNAMICS DRIVES THE TRANS/CIS ISOMERIZATION IN PHOTOACTIVE YELLOW PROTEIN: 200 NS TIME DELAY PHOTO-ACTIVATED (LIGHT) STRUCTURE
Descriptor:Photoactive yellow protein
Authors:Pande, K., Tenboer, J., Schmidt, M.
Deposit date:2016-01-04
Release date:2016-05-25
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein.
Science, 352, 2016
5HDC
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FEMTOSECOND STRUCTURAL DYNAMICS DRIVES THE TRANS/CIS ISOMERIZATION IN PHOTOACTIVE YELLOW PROTEIN: 100 FS TO 400 FS STRUCTURE
Descriptor:Photoactive yellow protein
Authors:Pande, K., Tenboer, J., Schmidt, M.
Deposit date:2016-01-05
Release date:2016-05-25
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein.
Science, 352, 2016
5HDD
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FEMTOSECOND STRUCTURAL DYNAMICS DRIVES THE TRANS/CIS ISOMERIZATION IN PHOTOACTIVE YELLOW PROTEIN: 800 FS TO 1200 FS STRUCTURE
Descriptor:Photoactive yellow protein
Authors:Pande, K., Tenboer, J., Schmidt, M.
Deposit date:2016-01-05
Release date:2016-05-25
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein.
Science, 352, 2016
5HDS
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FEMTOSECOND STRUCTURAL DYNAMICS DRIVES THE TRANS/CIS ISOMERIZATION IN PHOTOACTIVE YELLOW PROTEIN: 3 PS STRUCTURE
Descriptor:Photoactive yellow protein
Authors:Pande, K., Tenboer, J., Schmidt, M.
Deposit date:2016-01-05
Release date:2016-05-25
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein.
Science, 352, 2016
6B5X
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BETA-LACTAMASE, UNMIXED SHARDS CRYSTAL FORM
Descriptor:Beta-lactamase, PHOSPHATE ION
Authors:Pandey, S.
Deposit date:2017-09-29
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B5Y
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BETA-LACTAMASE, MIXED WITH CEFTRIAXONE, 30MS TIME POINT, SHARDS CRYSTAL FORM
Descriptor:Beta-lactamase, PHOSPHATE ION, Ceftriaxone
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-09-29
Release date:2018-06-27
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B68
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BETA-LACTAMASE, 100MS TIMEPOINT, MIXED, SHARDS CRYSTAL FORM
Descriptor:Beta-lactamase, PHOSPHATE ION, Ceftriaxone, ...
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B69
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BETA-LACTAMASE, 500MS TIMEPOINT, MIXED, SHARDS CRYSTAL FORM
Descriptor:Beta-lactamase, PHOSPHATE ION, Ceftriaxone, ...
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B6A
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BETA-LACTAMASE, 2SECS TIMEPOINT, MIXED, SHARDS CRYSTAL FORM
Descriptor:Beta-lactamase, PHOSPHATE ION, Ceftriaxone, ...
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B6B
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BETA-LACTAMASE, UNMIXED NEEDLES CRYSTAL FORM
Descriptor:Beta-lactamase
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B6C
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BETA-LACTAMASE, MIXED WITH CEFTRIAXONE, NEEDLES CRYSTAL FORM, 30MS
Descriptor:Beta-lactamase, Ceftriaxone
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B6D
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BETA-LACTAMASE, MIXED WITH CEFTRIAXONE, NEEDLES CRYSTAL FORM, 100MS
Descriptor:Beta-lactamase, (2R)-2-[(1S)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-2-hydroxyethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Ceftriaxone
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
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