6PL2
TRK-A IN COMPLEX WITH LIGAND 1a
Summary for 6PL2
Entry DOI | 10.2210/pdb6pl2/pdb |
Descriptor | High affinity nerve growth factor receptor, N-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-2-{[1-(4-hydroxyphenyl)-1H-tetrazol-5-yl]sulfanyl}acetamide (3 entities in total) |
Functional Keywords | trk-a kinase domain, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 35878.25 |
Authors | Subramanian, G. (deposition date: 2019-06-30, release date: 2019-09-04, Last modification date: 2019-09-25) |
Primary citation | Subramanian, G.,Bowen, S.J.,Zhu, Y.,Roush, N.,Zachary, T.,Javens, C.,Williams, T.,Janssen, A.,Gonzales, A. Type 2 inhibitor leads of human tropomyosin receptor kinase (hTrkA). Bioorg.Med.Chem.Lett., 29:126624-126624, 2019 Cited by PubMed: 31444087DOI: 10.1016/j.bmcl.2019.126624 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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