6PME

TRK-A IN COMPLEX WITH LIGAND

Summary for 6PME

Entry DOI	10.2210/pdb6pme/pdb
Related	6PMA 6PMB 6PMC
Descriptor	High affinity nerve growth factor receptor, ZINC ION, N-[2,4-bis(morpholin-4-yl)phenyl]-3-phenoxybenzamide, ... (5 entities in total)
Functional Keywords	trk-a kinase domain, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	108161.18
Authors	Subramanian, G.,Brown, D.G. (deposition date: 2019-07-01, release date: 2020-02-26, Last modification date: 2021-02-03)
Primary citation	Subramanian, G.,Vairagoundar, R.,Bowen, S.J.,Roush, N.,Zachary, T.,Javens, C.,Williams, T.,Janssen, A.,Gonzales, A. Synthetic inhibitor leads of human tropomyosin receptor kinase A ( h TrkA). Rsc Med Chem, 11:370-377, 2020 Cited by PubMed: 33479642 DOI: 10.1039/c9md00554d PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation