6PME
TRK-A IN COMPLEX WITH LIGAND
Summary for 6PME
Entry DOI | 10.2210/pdb6pme/pdb |
Related | 6PMA 6PMB 6PMC |
Descriptor | High affinity nerve growth factor receptor, ZINC ION, N-[2,4-bis(morpholin-4-yl)phenyl]-3-phenoxybenzamide, ... (5 entities in total) |
Functional Keywords | trk-a kinase domain, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 108161.18 |
Authors | Subramanian, G.,Brown, D.G. (deposition date: 2019-07-01, release date: 2020-02-26, Last modification date: 2021-02-03) |
Primary citation | Subramanian, G.,Vairagoundar, R.,Bowen, S.J.,Roush, N.,Zachary, T.,Javens, C.,Williams, T.,Janssen, A.,Gonzales, A. Synthetic inhibitor leads of human tropomyosin receptor kinase A ( h TrkA). Rsc Med Chem, 11:370-377, 2020 Cited by PubMed: 33479642DOI: 10.1039/c9md00554d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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