Author results

4DWR
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RNA LIGASE RTCB/MN2+ COMPLEX
Descriptor:tRNA-splicing ligase RtcB, SUCROSE, MANGANESE (II) ION, ...
Authors:Xia, S., Englert, M., Soll, D., Wang, J.
Deposit date:2012-02-26
Release date:2012-09-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH.
Proc.Natl.Acad.Sci.USA, 109, 2012
3AII
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ARCHAEAL NON-DISCRIMINATING GLUTAMYL-TRNA SYNTHETASE FROM METHANOTHERMOBACTER THERMAUTOTROPHICUS
Descriptor:Glutamyl-tRNA synthetase, ACETIC ACID, 1,2-ETHANEDIOL, ...
Authors:Nureki, O., Ishitani, R.
Deposit date:2010-05-14
Release date:2010-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of an archaeal non-discriminating glutamyl-tRNA synthetase: a missing link in the evolution of Gln-tRNAGln formation
Nucleic Acids Res., 2010
3A4M
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CRYSTAL STRUCTURE OF ARCHAEAL O-PHOSPHOSERYL-TRNA(SEC) KINASE
Descriptor:L-seryl-tRNA(Sec) kinase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Araiso, Y., Ishitani, R., Soll, D., Nureki, O.
Deposit date:2009-07-10
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.792 Å)
Cite:Structure of a tRNA-dependent kinase essential for selenocysteine decoding
Proc.Natl.Acad.Sci.USA, 106, 2009
2Q7E
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THE STRUCTURE OF PYRROLYSYL-TRNA SYNTHETASE BOUND TO AN ATP ANALOGUE
Descriptor:Pyrrolysyl-tRNA synthetase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Kavran, J.M., Steitz, T.A.
Deposit date:2007-06-06
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3A4L
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CRYSTAL STRUCTURE OF ARCHAEAL O-PHOSPHOSERYL-TRNA(SEC) KINASE
Descriptor:L-seryl-tRNA(Sec) kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:Araiso, Y., Ishitani, R., Soll, D., Nureki, O.
Deposit date:2009-07-10
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a tRNA-dependent kinase essential for selenocysteine decoding
Proc.Natl.Acad.Sci.USA, 106, 2009
2Q7G
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PYRROLYSINE TRNA SYNTHETASE BOUND TO A PYRROLYSINE ANALOGUE (CYC) AND ATP
Descriptor:Pyrrolysyl-tRNA synthetase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Kavran, J.M., Steitz, T.A.
Deposit date:2007-06-06
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3IP4
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THE HIGH RESOLUTION STRUCTURE OF GATCAB
Descriptor:Glutamyl-tRNA(Gln) amidotransferase subunit A, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, ...
Authors:Nakamura, A., Yao, M., Tanaka, I.
Deposit date:2009-08-17
Release date:2009-11-24
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Two distinct regions in Staphylococcus aureus GatCAB guarantee accurate tRNA recognition
Nucleic Acids Res., 38, 2010
3UH0
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CRYSTAL STRUCTURE OF THE YEAST MITOCHONDRIAL THREONYL-TRNA SYNTHETASE (MST1) IN COMPLEX WITH THREONYL SULFAMOYL ADENYLATE
Descriptor:Threonyl-tRNA synthetase, mitochondrial, ZINC ION, ...
Authors:Peterson, K.M., Ling, J., Simonovic, I., Cho, C., Soll, D., Simonovic, M.
Deposit date:2011-11-03
Release date:2012-02-22
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment.
Proc.Natl.Acad.Sci.USA, 109, 2012
4ZIB
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF PYLRS MUTANT BOUND WITH 3-BENZOTHIENYL-L-ALANINE AND ATP
Descriptor:Pyrrolysine--tRNA ligase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Nakamura, A., Guo, L.T., Wang, Y.S., Soll, D.
Deposit date:2015-04-28
Release date:2016-03-02
Method:X-RAY DIFFRACTION (2.054 Å)
Cite:Probing the active site tryptophan of Staphylococcus aureus thioredoxin with an analog.
Nucleic Acids Res., 43, 2015
2Q7H
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PYRROLYSYL-TRNA SYNTHETASE BOUND TO ADENYLATED PYRROLYSINE AND PYROPHOSPHATE
Descriptor:Pyrrolysyl-tRNA synthetase, 1,2-ETHANEDIOL, (2R)-2-AMINO-6-({[(2S,3R)-3-METHYLPYRROLIDIN-2-YL]CARBONYL}AMINO)HEXANOYL [(2S,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL HYDROGEN (R)-PHOSPHATE, ...
Authors:Kavran, J.M., Steitz, T.A.
Deposit date:2007-06-06
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2ZIM
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PYRROLYSYL-TRNA SYNTHETASE BOUND TO ADENYLATED PYRROLYSINE AND PYROPHOSPHATE
Descriptor:Pyrrolysyl-tRNA synthetase, 1,2-ETHANEDIOL, (2R)-2-AMINO-6-({[(2S,3R)-3-METHYLPYRROLIDIN-2-YL]CARBONYL}AMINO)HEXANOYL [(2S,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL HYDROGEN (R)-PHOSPHATE, ...
Authors:Steitz, T.A., Kavran, J.M.
Deposit date:2008-02-19
Release date:2008-03-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3UGQ
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CRYSTAL STRUCTURE OF THE APO FORM OF THE YEAST MITOCHONDRIAL THREONYL-TRNA SYNTHETASE DETERMINED AT 2.1 ANGSTROM RESOLUTION
Descriptor:Threonyl-tRNA synthetase, mitochondrial, ZINC ION, ...
Authors:Peterson, K.M., Ling, J., Simonovic, I., Cho, C., Soll, D., Simonovic, M.
Deposit date:2011-11-02
Release date:2012-02-22
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment.
Proc.Natl.Acad.Sci.USA, 109, 2012
3IEY
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CRYSTAL STRUCTURE OF THE FUNCTIONAL NANOARCHAEUM EQUITANS TRNA SPLICING ENDONUCLEASE
Descriptor:tRNA-splicing endonuclease, NEQ261
Authors:Mitchell, M., Li, H.
Deposit date:2009-07-23
Release date:2009-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structure and assembly of the functional Nanoarchaeum equitans tRNA splicing endonuclease.
Nucleic Acids Res., 37, 2009
4TQD
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF IFRS BOUND WITH 3-IODO-L-PHE AND ATP
Descriptor:Pyrrolysine--tRNA ligase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Nakamura, A., O'Donoghue, P., Soll, D.
Deposit date:2014-06-11
Release date:2014-11-12
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (2.1429 Å)
Cite:Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.
Proc.Natl.Acad.Sci.USA, 111, 2014
3MF2
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CRYSTAL STRUCTURE OF CLASS II AARS HOMOLOGUE (BLL0957) COMPLEXED WITH AMP
Descriptor:Bll0957 protein, ZINC ION, ADENOSINE MONOPHOSPHATE, ...
Authors:Weygand-Durasevic, I., Mocibob, M., Ivic, N., Bilokapic, S., Maier, T., Luic, M., Ban, N.
Deposit date:2010-04-01
Release date:2010-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
2CJA
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CRYSTAL STRUCTURE OF METHANOSARCINA BARKERI SERYL-TRNA SYNTHETASE COMPLEXED WITH ATP
Descriptor:SERYL-TRNA SYNTHETASE, ZINC ION, CHLORIDE ION, ...
Authors:Bilokapic, S., Maier, T., Ahel, D., Gruic-Sovulj, I., Soll, D., Weygand-Durasevic, I., Ban, N.
Deposit date:2006-03-30
Release date:2006-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition
Embo J., 25, 2006
3IF0
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CRYSTAL STRUCTURE OF THE NANOARCHAEUM EQUITANS TRNA SPLICING ENDONUCLEASE STRUCTURAL SUBUNIT
Descriptor:NEQ261
Authors:Mitchell, M., Li, H.
Deposit date:2009-07-23
Release date:2009-08-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure and assembly of the functional Nanoarchaeum equitans tRNA splicing endonuclease.
Nucleic Acids Res., 37, 2009
3MF1
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CRYSTAL STRUCTURE OF CLASS II AARS HOMOLOGUE (BLL0957) COMPLEXED WITH AN ANALOGUE OF GLYCYL ADENYLATE
Descriptor:Bll0957 protein, ZINC ION, 5'-O-(glycylsulfamoyl)adenosine
Authors:Weygand-Durasevic, I., Mocibob, M., Ivic, N., Bilokapic, S., Maier, T., Luic, M., Ban, N.
Deposit date:2010-04-01
Release date:2010-07-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
4DWQ
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RNA LIGASE RTCB-GMP/MN(2+) COMPLEX
Descriptor:tRNA-splicing ligase RtcB, GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ...
Authors:Okada, C., Xia, S., Englert, M., Yao, M., Soll, D., Wang, J.
Deposit date:2012-02-26
Release date:2012-09-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH.
Proc.Natl.Acad.Sci.USA, 109, 2012
4Q6G
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF ACKRS-1 BOUND WITH N-ACETYL-LYSINE AND ADPNP
Descriptor:Pyrrolysine--tRNA ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 1,2-ETHANEDIOL, ...
Authors:Eiler, D.R., Kavran, J., Steitz, T.A.
Deposit date:2014-04-22
Release date:2014-11-12
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.
Proc.Natl.Acad.Sci.USA, 111, 2014
2CJ9
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CRYSTAL STRUCTURE OF METHANOSARCINA BARKERI SERYL-TRNA SYNTHETASE COMPLEXED WITH AN ANALOG OF SERYLADENYLATE
Descriptor:SERYL-TRNA SYNTHETASE, ZINC ION, CHLORIDE ION, ...
Authors:Bilokapic, S., Maier, T., Ahel, D., Gruic-Sovulj, I., Soll, D., Weygand-Durasevic, I., Ban, N.
Deposit date:2006-03-29
Release date:2006-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition
Embo J., 25, 2006
3H0L
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STRUCTURE OF TRNA-DEPENDENT AMIDOTRANSFERASE GATCAB FROM AQUIFEX AEOLICUS
Descriptor:Glutamyl-tRNA(Gln) amidotransferase subunit A, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Glutamyl-tRNA(Gln) amidotransferase subunit C, ...
Authors:Wu, J., Bu, W., Sheppard, K., Kitabatake, M., Soll, D., Smith, J.L.
Deposit date:2009-04-09
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme
J.Mol.Biol., 391, 2009
4Y4O
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME WITH RRNA MODIFICATIONS AND BOUND TO PROTEIN Y (YFIA) AT 2.3A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Polikanov, Y.S., Melnikov, S.V., Soll, D., Steitz, T.A.
Deposit date:2015-02-10
Release date:2015-03-18
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol., 22, 2015
5UD5
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CRYSTAL STRUCTURE OF THE TRNA BINDING DOMAIN OF PYRROLYSYL-TRNA SYNTHETASE BOUND TO TRNA(PYL)
Descriptor:Pyrrolysine--tRNA ligase, RNA (70-MER), ZINC ION
Authors:Suzuki, T., Soll, D.
Deposit date:2016-12-23
Release date:2017-10-11
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Crystal structures reveal an elusive functional domain of pyrrolysyl-tRNA synthetase.
Nat. Chem. Biol., 13, 2017
3WBZ
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CRYSTAL STRUCTURE OF C. ALBICANS TRNA(HIS) GUANYLYLTRANSFERASE (THG1) WITH ATP
Descriptor:Likely histidyl tRNA-specific guanylyltransferase, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Nakamura, A., Nemoto, T., Sonoda, T., Yamashita, K., Tanaka, I., Yao, M.
Deposit date:2013-05-24
Release date:2013-12-18
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.392 Å)
Cite:Structural basis of reverse nucleotide polymerization
Proc.Natl.Acad.Sci.USA, 110, 2013
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