4TQF

Crystal Structure of the C-terminal domain of IFRS bound with 2-(5-bromothienyl)-L-Ala and ATP

Summary for 4TQF

DescriptorPyrrolysine--tRNA ligase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywordsamino acyl-trna synthetases, archaeal proteins, evolution, molecular, genetic code, substrate specificity, ligase
Biological sourceMethanosarcina mazei
Cellular locationCytoplasm  Q8PWY1
Total number of polymer chains1
Total molecular weight34639.6
Authors
Nakamura, A.,O'Donoghue, P.,Soll, D. (deposition date: 2014-06-11, release date: 2014-11-12, Last modification date: 2014-12-03)
Primary citation
Guo, L.T.,Wang, Y.S.,Nakamura, A.,Eiler, D.,Kavran, J.M.,Wong, M.,Kiessling, L.L.,Steitz, T.A.,O'Donoghue, P.,Soll, D.
Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.
Proc.Natl.Acad.Sci.USA, 111:16724-16729, 2014
PubMed: 25385624 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1419737111
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7143 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.20730.4%3.4%2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4tqf
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Molmil generated image of 4tqf
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More Biological unit images

Molmil generated image of 4tqf
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Molmil generated image of 4tqf
rotated about x axis by 90°
Molmil generated image of 4tqf
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4tqf.pdb1.gz [92.11 KB])
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