6N9E | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH A SHORT SUBSTRATE MIMIC CC-PMN AND BOUND TO MRNA AND P-SITE TRNA AT 3.7A RESOLUTION | | Descriptor: | 23S Ribosomal RNA, 5S Ribosomal RNA, 50S Ribosomal Protein L2, ... | | Authors: | Melnikov, S.V., Khabibullina, N.F., Mairhofer, E., Vargas-Rodriguez, O., Reynolds, N.M., Micura, R., Soll, D., Polikanov, Y.S. | | Deposit date: | 2018-12-03 | | Release date: | 2018-12-12 | | Last modified: | 2018-12-19 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.
Nucleic Acids Res., 2018
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6N9F | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH A SHORT SUBSTRATE MIMIC ACCA-DPHE AND BOUND TO MRNA AND P-SITE TRNA AT 3.7A RESOLUTION | | Descriptor: | 23S Ribosomal RNA, 5S Ribosomal RNA, 50S Ribosomal Protein L2, ... | | Authors: | Melnikov, S.V., Khabibullina, N.F., Mairhofer, E., Vargas-Rodriguez, O., Reynolds, N.M., Micura, R., Soll, D., Polikanov, Y.S. | | Deposit date: | 2018-12-03 | | Release date: | 2018-12-12 | | Last modified: | 2018-12-19 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.
Nucleic Acids Res., 2018
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5V6X | |
5UD5 | |
5J4B | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH CISPLATIN (CO-CRYSTALLIZED) AND BOUND TO MRNA AND A-, P- AND E-SITE TRNAS AT 2.6A RESOLUTION | | Descriptor: | 23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Melnikov, S.V., Soll, D., Steitz, T.A., Polikanov, Y.S. | | Deposit date: | 2016-03-31 | | Release date: | 2016-04-27 | | Last modified: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Nucleic Acids Res., 44, 2016
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5J4C | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH CISPLATIN (SOAKED) AND BOUND TO MRNA AND A-, P- AND E-SITE TRNAS AT 2.8A RESOLUTION | | Descriptor: | 23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Melnikov, S.V., Soll, D., Steitz, T.A., Polikanov, Y.S. | | Deposit date: | 2016-03-31 | | Release date: | 2016-04-27 | | Last modified: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Nucleic Acids Res., 44, 2016
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5IZK | |
5IZL | | THE CRYSTAL STRUCTURE OF HUMAN EEFSEC IN COMPLEX WITH GDPCP | | Descriptor: | Selenocysteine-specific elongation factor, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | Authors: | Dobosz-Bartoszek, M., Simonovic, M. | | Deposit date: | 2016-03-25 | | Release date: | 2016-10-12 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.72 Å) | | Cite: | Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
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5IZM | |
4ZIB | | CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF PYLRS MUTANT BOUND WITH 3-BENZOTHIENYL-L-ALANINE AND ATP | | Descriptor: | Pyrrolysine--tRNA ligase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Nakamura, A., Guo, L.T., Wang, Y.S., Soll, D. | | Deposit date: | 2015-04-28 | | Release date: | 2016-03-02 | | Method: | X-RAY DIFFRACTION (2.054 Å) | | Cite: | Probing the active site tryptophan of Staphylococcus aureus thioredoxin with an analog.
Nucleic Acids Res., 43, 2015
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4Y4O | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME WITH RRNA MODIFICATIONS AND BOUND TO PROTEIN Y (YFIA) AT 2.3A RESOLUTION | | Descriptor: | 23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Polikanov, Y.S., Melnikov, S.V., Soll, D., Steitz, T.A. | | Deposit date: | 2015-02-10 | | Release date: | 2015-03-18 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol., 22, 2015
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4Y4P | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME WITH RRNA MODIFICATIONS AND BOUND TO MRNA AND A-, P- AND E-SITE TRNAS AT 2.5A RESOLUTION | | Descriptor: | 23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Polikanov, Y.S., Melnikov, S.V., Soll, D., Steitz, T.A. | | Deposit date: | 2015-02-10 | | Release date: | 2015-03-18 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol., 22, 2015
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4WJ3 | | CRYSTAL STRUCTURE OF THE ASPARAGINE TRANSAMIDOSOME FROM PSEUDOMONAS AERUGINOSA | | Descriptor: | Glutamyl-tRNA(Gln) amidotransferase subunit A, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Glutamyl-tRNA(Gln) amidotransferase subunit C, ... | | Authors: | Suzuki, T., Nakamura, A., Kato, K., Tanaka, I., Yao, M. | | Deposit date: | 2014-09-29 | | Release date: | 2014-12-31 | | Last modified: | 2015-01-28 | | Method: | X-RAY DIFFRACTION (3.705 Å) | | Cite: | Structure of the Pseudomonas aeruginosa transamidosome reveals unique aspects of bacterial tRNA-dependent asparagine biosynthesis
Proc.Natl.Acad.Sci.USA, 112, 2015
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4WJ4 | | CRYSTAL STRUCTURE OF NON-DISCRIMINATING ASPARTYL-TRNA SYNTHETASE FROM PSEUDOMONAS AERUGINOSA COMPLEXED WITH TRNA(ASN) AND ASPARTIC ACID | | Descriptor: | Aspartate--tRNA(Asp/Asn) ligase, 76mer-tRNA, ASPARTIC ACID | | Authors: | Suzuki, T., Nakamura, A., Kato, K., Tanaka, I., Yao, M. | | Deposit date: | 2014-09-29 | | Release date: | 2014-12-31 | | Last modified: | 2015-01-28 | | Method: | X-RAY DIFFRACTION (3.294 Å) | | Cite: | Structure of the Pseudomonas aeruginosa transamidosome reveals unique aspects of bacterial tRNA-dependent asparagine biosynthesis
Proc.Natl.Acad.Sci.USA, 112, 2015
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4TQD | | CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF IFRS BOUND WITH 3-IODO-L-PHE AND ATP | | Descriptor: | Pyrrolysine--tRNA ligase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Nakamura, A., O'Donoghue, P., Soll, D. | | Deposit date: | 2014-06-11 | | Release date: | 2014-11-12 | | Last modified: | 2014-12-03 | | Method: | X-RAY DIFFRACTION (2.1429 Å) | | Cite: | Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4TQF | | CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF IFRS BOUND WITH 2-(5-BROMOTHIENYL)-L-ALA AND ATP | | Descriptor: | Pyrrolysine--tRNA ligase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Nakamura, A., O'Donoghue, P., Soll, D. | | Deposit date: | 2014-06-11 | | Release date: | 2014-11-12 | | Last modified: | 2014-12-03 | | Method: | X-RAY DIFFRACTION (2.7143 Å) | | Cite: | Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4Q6G | | CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF ACKRS-1 BOUND WITH N-ACETYL-LYSINE AND ADPNP | | Descriptor: | Pyrrolysine--tRNA ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 1,2-ETHANEDIOL, ... | | Authors: | Eiler, D.R., Kavran, J., Steitz, T.A. | | Deposit date: | 2014-04-22 | | Release date: | 2014-11-12 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3WKR | |
3WKS | |
3WCN | |
3WCO | |
3WBZ | | CRYSTAL STRUCTURE OF C. ALBICANS TRNA(HIS) GUANYLYLTRANSFERASE (THG1) WITH ATP | | Descriptor: | Likely histidyl tRNA-specific guanylyltransferase, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | Authors: | Nakamura, A., Nemoto, T., Sonoda, T., Yamashita, K., Tanaka, I., Yao, M. | | Deposit date: | 2013-05-24 | | Release date: | 2013-12-18 | | Last modified: | 2014-02-05 | | Method: | X-RAY DIFFRACTION (2.392 Å) | | Cite: | Structural basis of reverse nucleotide polymerization
Proc.Natl.Acad.Sci.USA, 110, 2013
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3WC0 | | CRYSTAL STRUCTURE OF C. ALBICANS TRNA(HIS) GUANYLYLTRANSFERASE (THG1) WITH GTP | | Descriptor: | Likely histidyl tRNA-specific guanylyltransferase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | Authors: | Nakamura, A., Nemoto, T., Sonoda, T., Yamashita, K., Tanaka, I., Yao, M. | | Deposit date: | 2013-05-24 | | Release date: | 2013-12-18 | | Last modified: | 2014-01-15 | | Method: | X-RAY DIFFRACTION (3.03 Å) | | Cite: | Structural basis of reverse nucleotide polymerization
Proc.Natl.Acad.Sci.USA, 110, 2013
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3WC1 | | CRYSTAL STRUCTURE OF C. ALBICANS TRNA(HIS) GUANYLYLTRANSFERASE (THG1) WITH A G-1 DELETED TRNA(HIS) | | Descriptor: | Likely histidyl tRNA-specific guanylyltransferase, 75-mer tRNA | | Authors: | Nakamura, A., Nemoto, T., Sonoda, T., Yamashita, K., Tanaka, I., Yao, M. | | Deposit date: | 2013-05-24 | | Release date: | 2013-12-18 | | Last modified: | 2014-01-15 | | Method: | X-RAY DIFFRACTION (4.18 Å) | | Cite: | Structural basis of reverse nucleotide polymerization
Proc.Natl.Acad.Sci.USA, 110, 2013
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3WC2 | | CRYSTAL STRUCTURE OF C. ALBICANS TRNA(HIS) GUANYLYLTRANSFERASE (THG1) WITH A TRNA(PHE)(GUG) | | Descriptor: | Likely histidyl tRNA-specific guanylyltransferase, 76mer-tRNA | | Authors: | Nakamura, A., Nemoto, T., Sonoda, T., Yamashita, K., Tanaka, I., Yao, M. | | Deposit date: | 2013-05-24 | | Release date: | 2013-12-18 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (3.641 Å) | | Cite: | Structural basis of reverse nucleotide polymerization
Proc.Natl.Acad.Sci.USA, 110, 2013
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