Author results

3EA1
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CRYSTAL STRUCTURE OF THE Y247S/Y251S MUTANT OF PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM BACILLUS THURINGIENSIS
分子名称:1-phosphatidylinositol phosphodiesterase, ZINC ION
著者Shi, X., Shao, C., Zhang, X., Zambonelli, C., Redfied, A.G., Head, J.F., Seaton, B.A., Roberts, M.F.
登録日2008-08-24
公開日2009-04-14
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Modulation of bacillus thuringiensis phosphatidylinositol-specific phospholipase C activity by mutations in the putative dimerization interface.
J.Biol.Chem., 284, 2009
3EA2
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CRYSTAL STRUCTURE OF THE MYO-INOSITOL BOUND Y247S/Y251S MUTANT OF PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM BACILLUS THURINGIENSIS
分子名称:1-phosphatidylinositol phosphodiesterase, 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, ZINC ION
著者Shi, X., Shao, C., Zhang, X., Zambonelli, C., Redfied, A.G., Head, J.F., Seaton, B.A., Roberts, M.F.
登録日2008-08-24
公開日2009-04-14
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Modulation of bacillus thuringiensis phosphatidylinositol-specific phospholipase C activity by mutations in the putative dimerization interface.
J.Biol.Chem., 284, 2009
3EA3
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CRYSTAL STRUCTURE OF THE Y246S/Y247S/Y248S/Y251S MUTANT OF PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM BACILLUS THURINGIENSIS
分子名称:1-phosphatidylinositol phosphodiesterase, MANGANESE (II) ION
著者Shi, X., Shao, C., Zhang, X., Zambonelli, C., Redfied, A.G., Head, J.F., Seaton, B.A., Roberts, M.F.
登録日2008-08-24
公開日2009-04-14
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Modulation of Bacillus thuringiensis Phosphatidylinositol-specific Phospholipase C Activity by Mutations in the Putative Dimerization Interface.
J.Biol.Chem., 284, 2009
5GWR
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4-HYDROXYISOLEUCINE DEHYDROGENASE COMPLEXED WITH NADH
分子名称:4-hydroxyisolecuine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 1,2-ETHANEDIOL
著者Shi, X., Miyakawa, T., Nakamura, A., Tanokura, M.
登録日2016-09-13
公開日2017-10-25
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers
Sci Rep, 7, 2017
5GWS
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4-HYDROXYISOLEUCINE DEHYDROGENASE COMPLEXED WITH NADH AND SUCCINATE
分子名称:4-hydroxyisolecuine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SUCCINIC ACID
著者Shi, X., Miyakawa, T., Nakamura, A., Tanokura, M.
登録日2016-09-13
公開日2017-10-25
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers.
Sci Rep, 7, 2017
5GWT
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4-HYDROXYISOLEUCINE DEHYDROGENASE MUTANT COMPLEXED WITH NADH AND SUCCINATE
分子名称:4-hydroxyisolecuine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SUCCINIC ACID
著者Shi, X., Miyakawa, T., Nakamura, A., Tanokura, M.
登録日2016-09-13
公開日2017-10-25
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers.
Sci Rep, 7, 2017
5GMI
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CRYSTAL STRUCTURE OF GRASP55 GRASP DOMAIN IN COMPLEX WITH JAM-C C-TERMINUS
分子名称:Golgi reassembly-stacking protein 2, Junctional adhesion molecule C
著者Shi, N., Shi, X., Morelli, X., Betzi, S., Huang, X.
登録日2016-07-14
公開日2017-05-24
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis
PLoS Genet., 13, 2017
5GMJ
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CRYSTAL STRUCTURE OF GRASP55 GRASP DOMAIN IN COMPLEX WITH JAM-B C-TERMINUS
分子名称:Golgi reassembly-stacking protein 2, Junctional adhesion molecule B
著者Shi, N., Shi, X., Morelli, X., Betzi, S., Huang, X.
登録日2016-07-14
公開日2017-05-24
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.986 Å)
主引用文献Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis
PLoS Genet., 13, 2017
5GML
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CRYSTAL STRUCTURE OF GRASP DOMAIN OF GRASP55 WITH N TERMINAL EXTRA RESIDUES
分子名称:Golgi reassembly-stacking protein 2
著者Shi, N., Shi, X., Morelli, X., Betzi, S., Huang, X.
登録日2016-07-14
公開日2017-07-19
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.546 Å)
主引用文献Structural relationship of the tandem PDZ tandem from Grasp55 and its implication in the unconventional secretion pathway
to be published
1VPT
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AS11 VARIANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYL-L-METHIONINE
分子名称:VP39, S-ADENOSYLMETHIONINE
著者Hodel, A.E., Gershon, P.D., Shi, X., Quiocho, F.A.
登録日1996-03-20
公開日1996-08-17
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The 1.85 A structure of vaccinia protein VP39: a bifunctional enzyme that participates in the modification of both mRNA ends.
Cell(Cambridge,Mass.), 85, 1996
4O6F
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STRUCTURAL BASIS OF ESTROGEN RECEPTOR ALPHA METHYLATION MEDIATED BY HISTONE METHYLTRANSFERASE SMYD2
分子名称:N-lysine methyltransferase SMYD2, Estrogen receptor, ZINC ION, ...
著者Jiang, Y., Trescott, L., Holcomb, J., Brunzelle, J., Sirinupong, N., Shi, X., Yang, Z.
登録日2013-12-20
公開日2014-03-26
最終更新日2014-10-08
実験手法X-RAY DIFFRACTION (2.822 Å)
主引用文献Structural Insights into Estrogen Receptor alpha Methylation by Histone Methyltransferase SMYD2, a Cellular Event Implicated in Estrogen Signaling Regulation.
J.Mol.Biol., 426, 2014
2OR2
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STRUCTURE OF THE W47A/W242A MUTANT OF BACTERIAL PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C
分子名称:1-phosphatidylinositol phosphodiesterase
著者Shao, C., Shi, X., Wehbi, H., Zambonelli, C., Head, J.F., Seaton, B.A., Roberts, M.F.
登録日2007-02-01
公開日2007-02-13
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Dimer structure of an interfacially impaired phosphatidylinositol-specific phospholipase C.
J.Biol.Chem., 282, 2007
3OQ5
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CRYSTAL STRUCTURE OF THE 3-MBT DOMAIN FROM HUMAN L3MBTL1 IN COMPLEX WITH P53K382ME1
分子名称:Lethal(3)malignant brain tumor-like protein, Cellular tumor antigen p53
著者Roy, S., West, L.E., Weiner, K.L., Hayashi, R., Shi, X., Appella, E., Gozani, O., Kutateladze, T.
登録日2010-09-02
公開日2010-09-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5005 Å)
主引用文献The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression.
J.Biol.Chem., 285, 2010
3TDL
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STRUCTURE OF HUMAN SERUM ALBUMIN IN COMPLEX WITH DAUDA
分子名称:Serum albumin, MYRISTIC ACID, 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid
著者Wang, Y., Luo, Z., Shi, X., Wang, H., Nie, L.
登録日2011-08-11
公開日2012-06-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin
Protein Sci., 20, 2011
4IW1
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HSA-FRUCTOSE COMPLEX
分子名称:Serum albumin, FRUCTOSE, PHOSPHATE ION, ...
著者Wang, Y., Yu, H., Shi, X., Huang, M.
登録日2013-01-23
公開日2013-04-24
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structural mechanism of ring-opening reaction of glucose by human serum albumin
J.Biol.Chem., 288, 2013
4IW2
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HSA-GLUCOSE COMPLEX
分子名称:Serum albumin, D-GLUCOSE IN LINEAR FORM, ALPHA-D-GLUCOSE, ...
著者Wang, Y., Yu, H., Shi, X., Luo, Z., Huang, M.
登録日2013-01-23
公開日2013-04-24
最終更新日2014-12-17
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structural mechanism of ring-opening reaction of glucose by human serum albumin
J.Biol.Chem., 288, 2013
4K2C
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HSA LIGAND FREE
分子名称:Serum albumin
著者Wang, Y., Luo, Z., Shi, X., Huang, M.
登録日2013-04-08
公開日2013-05-01
最終更新日2018-02-21
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献Structural mechanism of ring-opening reaction of glucose by human serum albumin.
J. Biol. Chem., 288, 2013
4TT2
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN COMPLEXED WITH H4(1-20)K5AC PEPTIDE
分子名称:ATPase family AAA domain-containing protein 2, Histone H4K5Ac
著者Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
登録日2014-06-19
公開日2014-12-24
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TT4
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN COMPLEXED WITH H3(1-21)K14AC PEPTIDE
分子名称:ATPase family AAA domain-containing protein 2, Histone H3(1-21)K4Ac, SULFATE ION, ...
著者Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
登録日2014-06-19
公開日2014-12-24
最終更新日2015-03-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TT6
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN DOUBLE MUTANT N1063A-Y1064A IN APO FORM
分子名称:ATPase family AAA domain-containing protein 2, SULFATE ION, CHLORIDE ION, ...
著者Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
登録日2014-06-19
公開日2014-12-24
最終更新日2015-03-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TTE
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN COMPLEXED WITH METHYL 3-AMINO-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)BENZOATE
分子名称:ATPase family AAA domain-containing protein 2, SULFATE ION, CHLORIDE ION, ...
著者Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
登録日2014-06-20
公開日2014-12-24
最終更新日2015-03-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TU4
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN COMPLEXED WITH 3-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-5-[(PHENYLSULFONYL)AMINO]BENZOICACID
分子名称:ATPase family AAA domain-containing protein 2, SULFATE ION, GLYCEROL, ...
著者Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
登録日2014-06-23
公開日2014-12-24
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TU6
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CRYSTAL STRUCTURE OF APO ATAD2A BROMODOMAIN WITH N1064 ALTERNATE CONFORMATION
分子名称:ATPase family AAA domain-containing protein 2, SULFATE ION
著者Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
登録日2014-06-23
公開日2014-12-24
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
5A0E
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CRYSTAL STRUCTURE OF CYCLOPHILIN D IN COMPLEX WITH CSA ANALOGUE, JW47.
分子名称:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL, JW47
著者Warne, J., Pryce, G., Hill, J., Shi, X., Lenneras, F., Puentes, F., Kip, M., Hilditch, L., Walker, P., Simone, M., Chan, A.W.E., Towers, G., Coker, A.R., Duchen, M., Szabadkai, G., Baker, D., Selwood, D.L.
登録日2015-04-19
公開日2015-12-30
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects Against Neuro-Degeneration in Experimental Multiple Sclerosis.
J.Biol.Chem., 291, 2016
4REY
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CRYSTAL STRUCTURE OF THE GRASP65-GM130 C-TERMINAL PEPTIDE COMPLEX
分子名称:Golgi reassembly-stacking protein 1, Golgin subfamily A member 2, SULFATE ION
著者Shi, N., Hu, F., Li, B.
登録日2014-09-24
公開日2015-09-23
最終更新日2016-11-23
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural Basis for the Interaction between the Golgi Reassembly-stacking Protein GRASP65 and the Golgi Matrix Protein GM130.
J.Biol.Chem., 290, 2015