7ORU
Non-structural protein 10 (nsp10) from SARS CoV-2 in complex with fragment VT00221
Summary for 7ORU
Entry DOI | 10.2210/pdb7oru/pdb |
Descriptor | Non-structural protein 10, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total) |
Functional Keywords | fragment, complex, small molecule, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) |
Total number of polymer chains | 1 |
Total formula weight | 13878.49 |
Authors | Talibov, V.O.,Kozielski, F.,Sele, C.,Lou, J.,Dong, D.,Wang, Q.,Shi, X.,Nyblom, M.,Rogstam, A.,Krojer, T.,Knecht, W.,Fisher, S.Z. (deposition date: 2021-06-06, release date: 2021-10-20, Last modification date: 2024-01-31) |
Primary citation | Kozielski, F.,Sele, C.,Talibov, V.O.,Lou, J.,Dong, D.,Wang, Q.,Shi, X.,Nyblom, M.,Rogstam, A.,Krojer, T.,Fisher, Z.,Knecht, W. Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16. Rsc Chem Biol, 3:44-55, 2022 Cited by PubMed: 35128408DOI: 10.1039/d1cb00135c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
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