5GWS
4-hydroxyisoleucine dehydrogenase complexed with NADH and succinate
Summary for 5GWS
| Entry DOI | 10.2210/pdb5gws/pdb |
| Related | 5GWR 5GWT |
| Descriptor | 4-hydroxyisolecuine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SUCCINIC ACID, ... (4 entities in total) |
| Functional Keywords | nadh-dependent, short-chain, dehydrogenase, reductase, oxidoreductase |
| Biological source | Bacillus thuringiensis |
| Total number of polymer chains | 4 |
| Total formula weight | 128434.99 |
| Authors | Shi, X.,Miyakawa, T.,Nakamura, A.,Tanokura, M. (deposition date: 2016-09-13, release date: 2017-10-25, Last modification date: 2023-11-08) |
| Primary citation | Shi, X.,Miyakawa, T.,Nakamura, A.,Hou, F.,Hibi, M.,Ogawa, J.,Kwon, Y.,Tanokura, M. Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers. Sci Rep, 7:13703-13703, 2017 Cited by PubMed: 29057974DOI: 10.1038/s41598-017-13978-w PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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