7ORV

Non-structural protein 10 (nsp10) from SARS CoV-2 in complex with fragment VT00239

Summary for 7ORV

Entry DOI	10.2210/pdb7orv/pdb
Descriptor	Non-structural protein 10, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total)
Functional Keywords	fragment, complex, small molecule, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
Total number of polymer chains	1
Total formula weight	13906.95
Authors	Talibov, V.O.,Kozielski, F.,Sele, C.,Lou, J.,Dong, D.,Wang, Q.,Shi, X.,Nyblom, M.,Rogstam, A.,Krojer, T.,Knecht, W.,Fisher, S.Z. (deposition date: 2021-06-06, release date: 2021-10-20, Last modification date: 2024-01-31)
Primary citation	Kozielski, F.,Sele, C.,Talibov, V.O.,Lou, J.,Dong, D.,Wang, Q.,Shi, X.,Nyblom, M.,Rogstam, A.,Krojer, T.,Fisher, Z.,Knecht, W. Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16. Rsc Chem Biol, 3:44-55, 2022 Cited by PubMed: 35128408 DOI: 10.1039/d1cb00135c PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation