Author results

3EA1
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CRYSTAL STRUCTURE OF THE Y247S/Y251S MUTANT OF PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM BACILLUS THURINGIENSIS
Descriptor:1-phosphatidylinositol phosphodiesterase, ZINC ION
Authors:Shi, X., Shao, C., Zhang, X., Zambonelli, C., Redfied, A.G., Head, J.F., Seaton, B.A., Roberts, M.F.
Deposit date:2008-08-24
Release date:2009-04-14
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Modulation of bacillus thuringiensis phosphatidylinositol-specific phospholipase C activity by mutations in the putative dimerization interface.
J.Biol.Chem., 284, 2009
3EA2
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CRYSTAL STRUCTURE OF THE MYO-INOSITOL BOUND Y247S/Y251S MUTANT OF PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM BACILLUS THURINGIENSIS
Descriptor:1-phosphatidylinositol phosphodiesterase, 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, ZINC ION
Authors:Shi, X., Shao, C., Zhang, X., Zambonelli, C., Redfied, A.G., Head, J.F., Seaton, B.A., Roberts, M.F.
Deposit date:2008-08-24
Release date:2009-04-14
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Modulation of bacillus thuringiensis phosphatidylinositol-specific phospholipase C activity by mutations in the putative dimerization interface.
J.Biol.Chem., 284, 2009
3EA3
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CRYSTAL STRUCTURE OF THE Y246S/Y247S/Y248S/Y251S MUTANT OF PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM BACILLUS THURINGIENSIS
Descriptor:1-phosphatidylinositol phosphodiesterase, MANGANESE (II) ION
Authors:Shi, X., Shao, C., Zhang, X., Zambonelli, C., Redfied, A.G., Head, J.F., Seaton, B.A., Roberts, M.F.
Deposit date:2008-08-24
Release date:2009-04-14
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Modulation of Bacillus thuringiensis Phosphatidylinositol-specific Phospholipase C Activity by Mutations in the Putative Dimerization Interface.
J.Biol.Chem., 284, 2009
5GWR
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4-HYDROXYISOLEUCINE DEHYDROGENASE COMPLEXED WITH NADH
Descriptor:4-hydroxyisolecuine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 1,2-ETHANEDIOL
Authors:Shi, X., Miyakawa, T., Nakamura, A., Tanokura, M.
Deposit date:2016-09-13
Release date:2017-10-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers
Sci Rep, 7, 2017
5GWS
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4-HYDROXYISOLEUCINE DEHYDROGENASE COMPLEXED WITH NADH AND SUCCINATE
Descriptor:4-hydroxyisolecuine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SUCCINIC ACID
Authors:Shi, X., Miyakawa, T., Nakamura, A., Tanokura, M.
Deposit date:2016-09-13
Release date:2017-10-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers.
Sci Rep, 7, 2017
5GWT
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4-HYDROXYISOLEUCINE DEHYDROGENASE MUTANT COMPLEXED WITH NADH AND SUCCINATE
Descriptor:4-hydroxyisolecuine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SUCCINIC ACID
Authors:Shi, X., Miyakawa, T., Nakamura, A., Tanokura, M.
Deposit date:2016-09-13
Release date:2017-10-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers.
Sci Rep, 7, 2017
5GMI
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CRYSTAL STRUCTURE OF GRASP55 GRASP DOMAIN IN COMPLEX WITH JAM-C C-TERMINUS
Descriptor:Golgi reassembly-stacking protein 2, Junctional adhesion molecule C
Authors:Shi, N., Shi, X., Morelli, X., Betzi, S., Huang, X.
Deposit date:2016-07-14
Release date:2017-05-24
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis
PLoS Genet., 13, 2017
5GMJ
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CRYSTAL STRUCTURE OF GRASP55 GRASP DOMAIN IN COMPLEX WITH JAM-B C-TERMINUS
Descriptor:Golgi reassembly-stacking protein 2, Junctional adhesion molecule B
Authors:Shi, N., Shi, X., Morelli, X., Betzi, S., Huang, X.
Deposit date:2016-07-14
Release date:2017-05-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.986 Å)
Cite:Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis
PLoS Genet., 13, 2017
5GML
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CRYSTAL STRUCTURE OF GRASP DOMAIN OF GRASP55 WITH N TERMINAL EXTRA RESIDUES
Descriptor:Golgi reassembly-stacking protein 2
Authors:Shi, N., Shi, X., Morelli, X., Betzi, S., Huang, X.
Deposit date:2016-07-14
Release date:2017-07-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.546 Å)
Cite:Structural relationship of the tandem PDZ tandem from Grasp55 and its implication in the unconventional secretion pathway
to be published
1VPT
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AS11 VARIANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYL-L-METHIONINE
Descriptor:VP39, S-ADENOSYLMETHIONINE
Authors:Hodel, A.E., Gershon, P.D., Shi, X., Quiocho, F.A.
Deposit date:1996-03-20
Release date:1996-08-17
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The 1.85 A structure of vaccinia protein VP39: a bifunctional enzyme that participates in the modification of both mRNA ends.
Cell(Cambridge,Mass.), 85, 1996
4O6F
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STRUCTURAL BASIS OF ESTROGEN RECEPTOR ALPHA METHYLATION MEDIATED BY HISTONE METHYLTRANSFERASE SMYD2
Descriptor:N-lysine methyltransferase SMYD2, Estrogen receptor, ZINC ION, ...
Authors:Jiang, Y., Trescott, L., Holcomb, J., Brunzelle, J., Sirinupong, N., Shi, X., Yang, Z.
Deposit date:2013-12-20
Release date:2014-03-26
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (2.822 Å)
Cite:Structural Insights into Estrogen Receptor alpha Methylation by Histone Methyltransferase SMYD2, a Cellular Event Implicated in Estrogen Signaling Regulation.
J.Mol.Biol., 426, 2014
2OR2
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STRUCTURE OF THE W47A/W242A MUTANT OF BACTERIAL PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C
Descriptor:1-phosphatidylinositol phosphodiesterase
Authors:Shao, C., Shi, X., Wehbi, H., Zambonelli, C., Head, J.F., Seaton, B.A., Roberts, M.F.
Deposit date:2007-02-01
Release date:2007-02-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Dimer structure of an interfacially impaired phosphatidylinositol-specific phospholipase C.
J.Biol.Chem., 282, 2007
3OQ5
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CRYSTAL STRUCTURE OF THE 3-MBT DOMAIN FROM HUMAN L3MBTL1 IN COMPLEX WITH P53K382ME1
Descriptor:Lethal(3)malignant brain tumor-like protein, Cellular tumor antigen p53
Authors:Roy, S., West, L.E., Weiner, K.L., Hayashi, R., Shi, X., Appella, E., Gozani, O., Kutateladze, T.
Deposit date:2010-09-02
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5005 Å)
Cite:The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression.
J.Biol.Chem., 285, 2010
3TDL
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STRUCTURE OF HUMAN SERUM ALBUMIN IN COMPLEX WITH DAUDA
Descriptor:Serum albumin, MYRISTIC ACID, 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid
Authors:Wang, Y., Luo, Z., Shi, X., Wang, H., Nie, L.
Deposit date:2011-08-11
Release date:2012-06-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin
Protein Sci., 20, 2011
4IW1
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HSA-FRUCTOSE COMPLEX
Descriptor:Serum albumin, beta-D-fructofuranose, PHOSPHATE ION, ...
Authors:Wang, Y., Yu, H., Shi, X., Huang, M.
Deposit date:2013-01-23
Release date:2013-04-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural mechanism of ring-opening reaction of glucose by human serum albumin
J.Biol.Chem., 288, 2013
4IW2
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HSA-GLUCOSE COMPLEX
Descriptor:Serum albumin, D-glucose, alpha-D-glucopyranose, ...
Authors:Wang, Y., Yu, H., Shi, X., Luo, Z., Huang, M.
Deposit date:2013-01-23
Release date:2013-04-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structural mechanism of ring-opening reaction of glucose by human serum albumin
J.Biol.Chem., 288, 2013
4K2C
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HSA LIGAND FREE
Descriptor:Serum albumin
Authors:Wang, Y., Luo, Z., Shi, X., Huang, M.
Deposit date:2013-04-08
Release date:2013-05-01
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Structural mechanism of ring-opening reaction of glucose by human serum albumin.
J. Biol. Chem., 288, 2013
4TT2
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN COMPLEXED WITH H4(1-20)K5AC PEPTIDE
Descriptor:ATPase family AAA domain-containing protein 2, Histone H4K5Ac
Authors:Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
Deposit date:2014-06-19
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TT4
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN COMPLEXED WITH H3(1-21)K14AC PEPTIDE
Descriptor:ATPase family AAA domain-containing protein 2, Histone H3(1-21)K4Ac, SULFATE ION, ...
Authors:Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
Deposit date:2014-06-19
Release date:2014-12-24
Last modified:2015-03-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TT6
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN DOUBLE MUTANT N1063A-Y1064A IN APO FORM
Descriptor:ATPase family AAA domain-containing protein 2, SULFATE ION, CHLORIDE ION, ...
Authors:Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
Deposit date:2014-06-19
Release date:2014-12-24
Last modified:2015-03-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TTE
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN COMPLEXED WITH METHYL 3-AMINO-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)BENZOATE
Descriptor:ATPase family AAA domain-containing protein 2, SULFATE ION, CHLORIDE ION, ...
Authors:Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
Deposit date:2014-06-20
Release date:2014-12-24
Last modified:2015-03-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TU4
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CRYSTAL STRUCTURE OF ATAD2A BROMODOMAIN COMPLEXED WITH 3-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-5-[(PHENYLSULFONYL)AMINO]BENZOICACID
Descriptor:ATPase family AAA domain-containing protein 2, SULFATE ION, GLYCEROL, ...
Authors:Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
Deposit date:2014-06-23
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
4TU6
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CRYSTAL STRUCTURE OF APO ATAD2A BROMODOMAIN WITH N1064 ALTERNATE CONFORMATION
Descriptor:ATPase family AAA domain-containing protein 2, SULFATE ION
Authors:Poncet-Montange, G., Zhan, Y., Bardenhagen, J., Petrocchi, A., Leo, E., Shi, X., Lee, G., Leonard, P., Geck Do, M., Cardozo, M., Palmer, W., Andersen, J., Jones, P., Ladbury, J.
Deposit date:2014-06-23
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
5A0E
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CRYSTAL STRUCTURE OF CYCLOPHILIN D IN COMPLEX WITH CSA ANALOGUE, JW47.
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL, JW47
Authors:Warne, J., Pryce, G., Hill, J., Shi, X., Lenneras, F., Puentes, F., Kip, M., Hilditch, L., Walker, P., Simone, M., Chan, A.W.E., Towers, G., Coker, A.R., Duchen, M., Szabadkai, G., Baker, D., Selwood, D.L.
Deposit date:2015-04-19
Release date:2015-12-30
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects Against Neuro-Degeneration in Experimental Multiple Sclerosis.
J.Biol.Chem., 291, 2016
4REY
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CRYSTAL STRUCTURE OF THE GRASP65-GM130 C-TERMINAL PEPTIDE COMPLEX
Descriptor:Golgi reassembly-stacking protein 1, Golgin subfamily A member 2, SULFATE ION
Authors:Shi, N., Hu, F., Li, B.
Deposit date:2014-09-24
Release date:2015-09-23
Last modified:2016-11-23
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural Basis for the Interaction between the Golgi Reassembly-stacking Protein GRASP65 and the Golgi Matrix Protein GM130.
J.Biol.Chem., 290, 2015
170172
PDB entries from 2020-10-21