9U9C

Crystal structure of NDM-1 in complex with hydrolyzed amoxicillin

This is a non-PDB format compatible entry.

Summary for 9U9C

• Entry DOI: 10.2210/pdb9u9c/pdb
• Descriptor: Metallo-beta-lactamase type 2, ZINC ION, (2~{R},4~{S})-2-[(1~{R})-1-[[(2~{R})-2-azanyl-2-(4-hydroxyphenyl)ethanoyl]amino]-2-oxidanyl-2-oxidanylidene-ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ... (4 entities in total)
• Functional Keywords: hydrolase, ndm-1
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 52357.52

Authors

Shi, X.,Zhang, Q.,Liu, W. (deposition date: 2025-03-27, release date: 2025-07-09)

• Primary citation: Shi, X.,Yang, H.,Dai, Y.,Zhao, H.,Li, Y.,Li, Y.,Zhou, X.,Yan, H.,Zhang, Q.,Liu, W.; Crystal structure reveals the hydrophilic R1 group impairs NDM-1-ligand binding via water penetration at L3; J Struct Biol X, :100133-, 2025; DOI: 10.1016/j.yjsbx.2025.100133

Experimental method

X-RAY DIFFRACTION (1.25 Å)