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2WBU
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CRYSTAL STRUCTURE OF THE ZINC FINGER DOMAIN OF KLF4 BOUND TO ITS TARGET DNA
分子名称:KRUEPPEL-LIKE FACTOR 4, 5'-D(*DGP*DAP*DGP*DGP*DCP*DGP*DTP* DGP*DGP*DC)-3', 5'-D(*DGP*DCP*DCP*DAP*DCP*DGP*DCP* DCP*DTP*DC)-3', ...
著者Schuetz, A., Zocher, G., Carstanjen, D., Heinemann, U.
登録日2009-03-05
公開日2010-04-07
最終更新日2011-10-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation.
Cell.Mol.Life Sci., 68, 2011
4ULW
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CRYSTAL STRUCTURE OF THE ROQ-DOMAIN OF HUMAN ROQUIN1
分子名称:ROQUIN-1
著者Schuetz, A., Heinemann, U.
登録日2014-05-14
公開日2015-01-14
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Roquin Binding to Target Mrnas Involves a Winged Helix-Turn- Helix Motif.
Nat.Commun., 5, 2014
5N7H
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CRYSTAL STRUCTURE OF THE COILED-COIL DOMAIN OF HUMAN TRICELLULIN
分子名称:MARVEL domain-containing protein 2
著者Schuetz, A., Heinemann, U.
登録日2017-02-20
公開日2017-07-12
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the tricellulin C-terminal coiled-coil domain reveals a unique mode of dimerization.
Ann. N. Y. Acad. Sci., 1405, 2017
5N7I
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CRYSTAL STRUCTURE OF THE COILED-COIL DOMAIN OF HUMAN TRICELLULIN
分子名称:MARVEL domain-containing protein 2
著者Schuetz, A., Heinemann, U.
登録日2017-02-20
公開日2017-07-12
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Crystal structure of the tricellulin C-terminal coiled-coil domain reveals a unique mode of dimerization.
Ann. N. Y. Acad. Sci., 1405, 2017
5N7K
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CRYSTAL STRUCTURE OF THE COILED-COIL DOMAIN OF HUMAN TRICELLULIN
分子名称:MARVEL domain-containing protein 2
著者Schuetz, A., Heinemann, U.
登録日2017-02-20
公開日2017-07-12
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystal structure of the tricellulin C-terminal coiled-coil domain reveals a unique mode of dimerization.
Ann. N. Y. Acad. Sci., 1405, 2017
1Z4R
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HUMAN GCN5 ACETYLTRANSFERASE
分子名称:General control of amino acid synthesis protein 5-like 2, ACETYL COENZYME *A
著者Dong, A., Bernstein, G., Schuetz, A., Antoshenko, T., Wu, H., Loppnau, P., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Plotnikov, A., Structural Genomics Consortium (SGC)
登録日2005-03-16
公開日2005-03-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structure of a binary complex between human GCN5 histone acetyltransferase domain and acetyl coenzyme A
Proteins, 68, 2007
2GNQ
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STRUCTURE OF WDR5
分子名称:WD-repeat protein 5, CHLORIDE ION
著者Min, J., Schuetz, A., Allali-Hassani, A., Loppnau, P., Vedadi, M., Weigelt, J., Sundstrom, M., Edwards, A.M., Arrowsmith, C.H., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2006-04-10
公開日2006-06-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
2H9L
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WDR5DELTA23
分子名称:WD-repeat protein 5, SULFATE ION
著者Min, J.R., Schuetz, A., Allali-Hassani, A., Martin, F., Loppnau, P., Vedadi, M., Weigelt, J., Sundstrom, M., Edwards, A.M., Arrowsmith, C.H., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2006-06-10
公開日2006-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
2H9M
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WDR5 IN COMPLEX WITH UNMODIFIED H3K4 PEPTIDE
分子名称:WD-repeat protein 5, H3 histone
著者Min, J.R., Schuetz, A., Allali-Hassani, A., Martin, F., Loppnau, P., Vedadi, M., Weigelt, J., Sundstrom, M., Edwards, A.M., Arrowsmith, C.H., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2006-06-10
公開日2006-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
2H9N
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WDR5 IN COMPLEX WITH MONOMETHYLATED H3K4 PEPTIDE
分子名称:WD-repeat protein 5, H3 histone
著者Min, J.R., Schuetz, A., Allali-Hassani, A., Martin, F., Loppnau, P., Vedadi, M., Weigelt, J., Sundstrom, M., Edwards, A.M., Arrowsmith, C.H., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2006-06-10
公開日2006-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
2H9P
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WDR5 IN COMPLEX WITH TRIMETHYLATED H3K4 PEPTIDE
分子名称:WD-repeat protein 5, H3 histone
著者Min, J.R., Schuetz, A., Allali-Hassani, A., Martin, F., Loppnau, P., Vedadi, M., Weigelt, J., Sundstrom, M., Edwards, A.M., Arrowsmith, C.H., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2006-06-10
公開日2006-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
2O9K
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WDR5 IN COMPLEX WITH DIMETHYLATED H3K4 PEPTIDE
分子名称:WD repeat protein 5, H3 HISTONE
著者Min, J.R., Schuetz, A., Allali-Hassani, A., Martin, F., Loppnau, P., Vedadi, M., Weigelt, J., Sundstrom, M., Edwards, A.M., Arrowsmith, C.H., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2006-12-13
公開日2006-12-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis for Molecular Recognition and Presentation of Histone H3 by Wdr5.
Embo J., 25, 2006
3C0Y
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN HISTONE DEACETYLASE HDAC7
分子名称:Histone deacetylase 7a, ZINC ION, POTASSIUM ION
著者Min, J.R., Schuetz, A., Allali-Hassani, A., Loppnau, P., Kwiatkowski, N.P., Mazitschek, R., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Vedadi, M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2008-01-21
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity.
J.Biol.Chem., 283, 2008
2GL8
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HUMAN RETINOIC ACID RECEPTOR RXR-GAMMA LIGAND-BINDING DOMAIN
分子名称:Retinoic acid receptor RXR-gamma
著者Min, J.R., Schuetz, A., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2006-04-04
公開日2006-04-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structure of Human Retinoic acid receptor RXR-gamma ligand-binding domain.
To be Published
2PSW
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HUMAN MAK3 HOMOLOG IN COMPLEX WITH COA
分子名称:N-acetyltransferase 13, COENZYME A
著者Walker, J.R., Schuetz, A., Antoshenko, T., Wu, H., Bernstein, G., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2007-05-07
公開日2007-06-05
最終更新日2011-08-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of Human MAK3 homolog.
To be Published
3C0Z
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN HISTONE DEACETYLASE HDAC7 IN COMPLEX WITH SAHA
分子名称:Histone deacetylase 7a, ZINC ION, POTASSIUM ION, ...
著者Min, J., Schuetz, A., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2008-01-21
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity.
J.Biol.Chem., 283, 2008
3C10
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN HISTONE DEACETYLASE HDAC7 IN COMPLEX WITH TRICHOSTATIN A (TSA)
分子名称:Histone deacetylase 7a, ZINC ION, POTASSIUM ION, ...
著者Min, J., Schuetz, A., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2008-01-21
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity.
J.Biol.Chem., 283, 2008
2WBS
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CRYSTAL STRUCTURE OF THE ZINC FINGER DOMAIN OF KLF4 BOUND TO ITS TARGET DNA
分子名称:KRUEPPEL-LIKE FACTOR 4, 5'-D(*GP*AP*GP*GP*CP*GP*CP)-3', 5'-D(*GP*CP*GP*CP*CP*TP*CP)-3', ...
著者Zocher, G., Schuetz, A., Carstanjen, D., Heinemann, U.
登録日2009-03-03
公開日2010-04-07
最終更新日2011-10-05
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation.
Cell.Mol.Life Sci., 68, 2011
3TT9
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CRYSTAL STRUCTURE OF THE STABLE DEGRADATION FRAGMENT OF HUMAN PLAKOPHILIN 2 ISOFORM A (PKP2A) C752R VARIANT
分子名称:Plakophilin-2, GLYCEROL
著者Schuetz, A., Roske, Y., Gerull, B., Heinemann, U.
登録日2011-09-14
公開日2012-08-01
最終更新日2012-09-05
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations.
Circ Cardiovasc Genet, 5, 2012
5MR7
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CRYSTAL STRUCTURE OF THE DBD DOMAIN OF HUMAN GRHL2
分子名称:Grainyhead-like protein 2 homolog
著者Schuetz, A., Ming, Q., Roske, Y., Heinemann, U.
登録日2016-12-21
公開日2018-01-17
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Nucleic Acids Res., 46, 2018
6EKS
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VIBRIO CHOLERAE NEURAMINIDASE COMPLEXED WITH OSELTAMIVIR CARBOXYLATE
分子名称:Sialidase, CALCIUM ION, GLYCEROL, ...
著者Schuetz, A., Heinemann, U.
登録日2017-09-27
公開日2017-11-29
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Different Inhibitory Potencies of Oseltamivir Carboxylate, Zanamivir, and Several Tannins on Bacterial and Viral Neuraminidases as Assessed in a Cell-Free Fluorescence-Based Enzyme Inhibition Assay.
Molecules, 22, 2017
6EKU
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VIBRIO CHOLERAE NEURAMINIDASE COMPLEXED WITH ZANAMIVIR
分子名称:Sialidase, ZANAMIVIR, GLYCEROL, ...
著者Schuetz, A., Heinemann, U.
登録日2017-09-27
公開日2017-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Different Inhibitory Potencies of Oseltamivir Carboxylate, Zanamivir, and Several Tannins on Bacterial and Viral Neuraminidases as Assessed in a Cell-Free Fluorescence-Based Enzyme Inhibition Assay.
Molecules, 22, 2017
3C5K
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CRYSTAL STRUCTURE OF HUMAN HDAC6 ZINC FINGER DOMAIN
分子名称:Histone deacetylase 6, ZINC ION
著者Dong, A., Ravichandran, M., Schuetz, A., Loppnau, P., Li, Y., MacKenzie, F., Kozieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Bountra, C., Bochkarev, A., Dhe-Paganon, S., Min, J., Ouyang, H., Structural Genomics Consortium (SGC)
登録日2008-01-31
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal Structure of Human HDAC6 zinc finger domain.
To be Published
3CQV
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CRYSTAL STRUCTURE OF REVERB BETA IN COMPLEX WITH HEME
分子名称:Nuclear receptor subfamily 1 group D member 2, PROTOPORPHYRIN IX CONTAINING FE
著者Xu, X., Dong, A., Pardee, K.I., Reinking, J., Krause, H., Schuetz, A., Zhang, R., Cui, H., Edwards, A., Arrowsmith, C.H., Weigelt, J., Bountra, C., Savchenko, A., Botchkarev, A., Structural Genomics Consortium (SGC)
登録日2008-04-03
公開日2008-08-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta.
Plos Biol., 7, 2009
2B4Y
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CRYSTAL STRUCTURE OF HUMAN SIRTUIN HOMOLOG 5
分子名称:NAD-dependent deacetylase sirtuin-5, ZINC ION, ADENOSINE-5-DIPHOSPHORIBOSE, ...
著者Min, J.R., Antoshenko, T., Dong, A., Schuetz, A., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2005-09-27
公開日2006-02-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Human Sirtuin homolog 5 in complex with NAD
To be Published
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