3CQV

Crystal structure of Reverb beta in complex with heme

Summary for 3CQV

• Entry DOI: 10.2210/pdb3cqv/pdb
• Descriptor: Nuclear receptor subfamily 1 group D member 2, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• Functional Keywords: reverb beta, heme, nr1d2, nuclear receptor, dna-binding, metal-binding, nucleus, repressor, transcription, transcription regulation, zinc, zinc-finger, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus (By similarity): Q14995
• Total number of polymer chains: 1
• Total formula weight: 23486.51

Authors

Xu, X.,Dong, A.,Pardee, K.I.,Reinking, J.,Krause, H.,Schuetz, A.,Zhang, R.,Cui, H.,Edwards, A.,Arrowsmith, C.H.,Weigelt, J.,Bountra, C.,Savchenko, A.,Botchkarev, A.,Structural Genomics Consortium (SGC) (deposition date: 2008-04-03, release date: 2008-08-05, Last modification date: 2011-07-13)

• Primary citation: Pardee, K.I.,Xu, X.,Reinking, J.,Schuetz, A.,Dong, A.,Liu, S.,Zhang, R.,Tiefenbach, J.,Lajoie, G.,Plotnikov, A.N.,Botchkarev, A.,Krause, H.M.,Edwards, A.; The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta.; Plos Biol., 7:e43-e43, 2009; PubMed: 19243223; DOI: 10.1371/journal.pbio.1000043

Experimental method

X-RAY DIFFRACTION (1.9 Å)