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4H56
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CRYSTAL STRUCTURE OF THE CLOSTRIDIUM PERFRINGENS NETB TOXIN IN THE MEMBRANE INSERTED FORM
Descriptor:Necrotic enteritis toxin B
Authors:Savva, C.G., Fernandes da Costa, S.P., Bokori-Brown, M., Naylor, C., Cole, A.R., Moss, D.S., Titball, R.W., Basak, A.K.
Deposit date:2012-09-18
Release date:2012-12-26
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Molecular Architecture and Functional Analysis of NetB, a Pore-forming Toxin from Clostridium perfringens.
J.Biol.Chem., 288, 2013
5GAQ
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CRYO-EM STRUCTURE OF THE LYSENIN PORE
Descriptor:Lysenin
Authors:Savva, C.G., Bokori-Brown, M., Martin, T.G., Titball, R.W., Naylor, C.E., Basak, A.K.
Deposit date:2016-01-05
Release date:2016-04-06
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein
Nat Commun, 7, 2016
1NKT
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CRYSTAL STRUCTURE OF THE SECA PROTEIN TRANSLOCATION ATPASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEX WITH ADPBS
Descriptor:Preprotein translocase secA 1 subunit, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Sharma, V., Arockiasamy, A., Ronning, D.R., Savva, C.G., Holzenburg, A., Braunstein, M., Jacobs Jr., W.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-01-03
Release date:2003-03-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Crystal Structure of M. tuberculosis SecA, A Preprotein Translocating ATPase
Proc.Natl.Acad.Sci.USA, 100, 2003
1NL3
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CRYSTAL STRUCTURE OF THE SECA PROTEIN TRANSLOCATION ATPASE FROM MYCOBACTERIUM TUBERCULOSIS IN APO FORM
Descriptor:PREPROTEIN TRANSLOCASE SECA 1 SUBUNIT
Authors:Sharma, V., Arockiasamy, A., Ronning, D.R., Savva, C.G., Holzenburg, A., Braunstein, M., Jacobs Jr., W.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-01-06
Release date:2003-03-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of M. tuberculosis SecA, A Preprotein Translocating ATPase
Proc.Natl.Acad.Sci.USA, 100, 2003
2YPW
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ATOMIC MODEL FOR THE N-TERMINUS OF TRAO FITTED IN THE FULL-LENGTH STRUCTURE OF THE BACTERIAL PKM101 TYPE IV SECRETION SYSTEM CORE COMPLEX
Descriptor:TRAO
Authors:Rivera-Calzada, A., Fronzes, R., Savva, C.G., Chandran, V., Lian, P.W., Laeremans, T., Pardon, E., Steyaert, J., Remaut, H., Waksman, G., Orlova, E.V.
Deposit date:2012-11-02
Release date:2013-04-03
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (12.4 Å)
Cite:Structure of a Bacterial Type Iv Secretion Core Complex at Subnanometre Resolution.
Embo J., 32, 2013
3J80
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CRYOEM STRUCTURE OF 40S-EIF1-EIF1A PREINITIATION COMPLEX
Descriptor:18S rRNA, uS2, eS1, ...
Authors:Hussain, T., Llacer, J.L., Fernandez, I.S., Savva, C.G., Ramakrishnan, V.
Deposit date:2014-08-28
Release date:2014-11-05
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
3J81
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CRYOEM STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX
Descriptor:18S rRNA, uS2, eS1, ...
Authors:Hussain, T., Llacer, J.L., Fernandez, I.S., Savva, C.G., Ramakrishnan, V.
Deposit date:2014-08-29
Release date:2014-11-05
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
3ZBI
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FITTING RESULT IN THE O-LAYER OF THE SUBNANOMETER STRUCTURE OF THE BACTERIAL PKM101 TYPE IV SECRETION SYSTEM CORE COMPLEX DIGESTED WITH ELASTASE
Descriptor:TRAF PROTEIN, TRAO PROTEIN, TRAN PROTEIN
Authors:Rivera-Calzada, A., Fronzes, R., Savva, C.G., Chandran, V., Lian, P.W., Laeremans, T., Pardon, E., Steyaert, J., Remaut, H., Waksman, G., Orlova, E.V.
Deposit date:2012-11-10
Release date:2013-04-03
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Structure of a Bacterial Type Iv Secretion Core Complex at Subnanometre Resolution.
Embo J., 32, 2013
3ZBJ
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FITTING RESULTS IN THE I-LAYER OF THE SUBNANOMETER STRUCTURE OF THE BACTERIAL PKM101 TYPE IV SECRETION SYSTEM CORE COMPLEX DIGESTED WITH ELASTASE
Descriptor:TRAO PROTEIN
Authors:Rivera-Calzada, A., Fronzes, R., Savva, C.G., Chandran, V., Lian, P.W., Laeremans, T., Pardon, E., Steyaert, J., Remaut, H., Waksman, G., Orlova, E.V.
Deposit date:2012-11-10
Release date:2013-04-03
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Structure of a Bacterial Type Iv Secretion Core Complex at Subnanometre Resolution.
Embo J., 32, 2013
3ZIW
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CLOSTRIDIUM PERFRINGENS ENTEROTOXIN, D48A MUTATION AND N-TERMINAL 37 RESIDUES DELETED
Descriptor:HEAT-LABILE ENTEROTOXIN B CHAIN, HEXAETHYLENE GLYCOL
Authors:Yelland, T., Naylor, C.E., Savva, C.G., Basak, A.K.
Deposit date:2013-01-14
Release date:2014-01-29
Last modified:2014-08-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a C. Perfringens Enterotoxin Mutant in Complex with a Modified Claudin-2 Extracellular Loop 2
J.Mol.Biol., 426, 2014
3ZIX
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CLOSTRIDIUM PERFRINGENS ENTEROTOXIN WITH THE N-TERMINAL 37 RESIDUES DELETED
Descriptor:HEAT-LABILE ENTEROTOXIN B CHAIN, HEXAETHYLENE GLYCOL
Authors:Yelland, T., Naylor, C.E., Savva, C.G., Basak, A.K.
Deposit date:2013-01-14
Release date:2014-01-29
Last modified:2014-08-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a C. Perfringens Enterotoxin Mutant in Complex with a Modified Claudin-2 Extracellular Loop 2
J.Mol.Biol., 426, 2014
3ZJX
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CLOSTRIDIUM PERFRINGENS EPSILON TOXIN MUTANT H149A BOUND TO OCTYL GLUCOSIDE
Descriptor:EPSILON-TOXIN, B-OCTYLGLUCOSIDE, PHOSPHATE ION
Authors:Bokori-Brown, M., Kokkinidou, M.C., Savva, C.G., Fernandes da Costa, S.P., Naylor, C.E., Cole, A.R., Basak, A.K., Titball, R.W.
Deposit date:2013-01-20
Release date:2013-03-27
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Clostridium Perfringens Epsilon Toxin H149A Mutant as a Platform for Receptor Binding Studies.
Protein Sci., 22, 2013
5IT7
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STRUCTURE OF THE KLUYVEROMYCES LACTIS 80S RIBOSOME IN COMPLEX WITH THE CRICKET PARALYSIS VIRUS IRES AND EEF2
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Murray, J., Savva, C.G., Shin, B.S., Dever, T.E., Ramakrishnan, V., Fernandez, I.S.
Deposit date:2016-03-16
Release date:2016-05-18
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural characterization of ribosome recruitment and translocation by type IV IRES.
Elife, 5, 2016
5IT9
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STRUCTURE OF THE YEAST KLUYVEROMYCES LACTIS SMALL RIBOSOMAL SUBUNIT IN COMPLEX WITH THE CRICKET PARALYSIS VIRUS IRES.
Descriptor:Ribosomal protein uS2, Ribosomal protein eS1, Ribosomal protein uS5, ...
Authors:Murray, J., Savva, C.G., Shin, B.S., Dever, T.E., Ramakrishnan, V., Fernandez, I.S.
Deposit date:2016-03-16
Release date:2016-05-18
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural characterization of ribosome recruitment and translocation by type IV IRES.
Elife, 5, 2016
2NVO
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CRYSTAL STRUCTURE OF DEINOCOCCUS RADIODURANS RO (RSR) PROTEIN
Descriptor:Ro sixty-related protein, RSR, CALCIUM ION
Authors:Ramesh, A., Sacchettini, J.C.
Deposit date:2006-11-13
Release date:2007-03-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal structure of Rsr, an ortholog of the antigenic Ro protein, links conformational flexibility to RNA binding activity.
J.Biol.Chem., 282, 2007
2YGT
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CLOSTRIDIUM PERFRINGENS DELTA-TOXIN
Descriptor:DELTA TOXIN, ZINC ION, IMIDAZOLE, ...
Authors:Huyet, J., Naylor, C.E., Gibert, M., Popoff, M.R., Basak, A.K.
Deposit date:2011-04-20
Release date:2012-05-16
Last modified:2016-04-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insights Into Clostridium Perfringens Delta Toxin Pore Formation.
Plos One, 8, 2013
3ONR
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CRYSTAL STRUCTURE OF THE CALCIUM CHELATING IMMUNODOMINANT ANTIGEN, CALCIUM DODECIN (RV0379),FROM MYCOBACTERIUM TUBERCULOSIS WITH A NOVEL CALCIUM-BINDING SITE
Descriptor:PROTEIN TRANSPORT PROTEIN SECE2, CALCIUM ION, FORMIC ACID, ...
Authors:Arulandu, A., Sacchettini, J.C.
Deposit date:2010-08-30
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of calcium dodecin (Rv0379), from Mycobacterium tuberculosis with a unique calcium-binding site.
Protein Sci., 20, 2011
4P5H
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STRUCTURE OF CLOSTRIDIUM PERFRINGENS ENTEROTOXIN WITH A PEPTIDE DERIVED FROM A MODIFIED VERSION OF ECL-2 OF CLAUDIN 2
Descriptor:Claudin-2, Heat-labile enterotoxin B chain
Authors:Naylor, C.E., Yelland, T.S., Basak, A.K.
Deposit date:2014-03-17
Release date:2014-07-16
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:Structure of a C. perfringens Enterotoxin Mutant in Complex with a Modified Claudin-2 Extracellular Loop 2.
J.Mol.Biol., 426, 2014
5LJV
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MAMK DOUBLE HELICAL FILAMENT
Descriptor:Actin-like ATPase, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Lowe, J.
Deposit date:2016-07-21
Release date:2016-11-16
Last modified:2018-10-10
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:X-ray and cryo-EM structures of monomeric and filamentous actin-like protein MamK reveal changes associated with polymerization.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5LJW
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MAMK NON-POLYMERISING A278D MUTANT BOUND TO AMPPNP
Descriptor:Actin-like ATPase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Lowe, J.
Deposit date:2016-07-20
Release date:2016-11-16
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray and cryo-EM structures of monomeric and filamentous actin-like protein MamK reveal changes associated with polymerization.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5GAM
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FOOT REGION OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP
Descriptor:U5 snRNA, Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, ...
Authors:Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K.
Deposit date:2015-12-15
Release date:2016-02-03
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Angstrom resolution
Nature, 530, 2016
5GAN
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THE OVERALL STRUCTURE OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP AT 3.7 ANGSTROM
Descriptor:U4 snRNA, U6 snRNA, Pre-mRNA-splicing factor 8, ...
Authors:Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
5GAO
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HEAD REGION OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP
Descriptor:Small nuclear ribonucleoprotein-associated protein B, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, ...
Authors:Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
5MPS
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STRUCTURE OF A SPLICEOSOME REMODELED FOR EXON LIGATION
Descriptor:Yeast UBC4 gene for ubiquitin-conjugating enzyme, UBC4 gene exon, U2 snRNA, ...
Authors:Fica, S.M., Oubridge, C., Galej, W.P., Wilkinson, M.E., Newman, A.J., Bai, X.-C., Nagai, K.
Deposit date:2016-12-18
Release date:2017-01-18
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5MQ0
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STRUCTURE OF A SPLICEOSOME REMODELED FOR EXON LIGATION
Descriptor:Yeast UBC4 gene for ubiquitin-conjugating enzyme, 5'-EXON OF UBC4 PRE-MRNA, S.cerevisiae chromosome II reading frame ORF YBR230c, ...
Authors:Fica, S.M., Oubridge, C., Galej, W.P., Wilkinson, M.E., Newman, A.J., Bai, X.-C., Nagai, K.
Deposit date:2016-12-19
Release date:2017-01-18
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
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